Neoadjuvant Radiation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A phase II open-label randomized clinical trial of preoperative durvalumab or durvalumab plus tremelimumab in resectable head and neck squamous cell carcinoma
CONCLUSIONS: Preoperative D+/-T is feasible and may benefit patients with resectable HNSCC. Distinct changes in the tumor microenvironment and circulating immune cells were induced by each treatment regimen, warranting further investigation.PMID:38457288 | DOI:10.1158/1078-0432.CCR-23-3249 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - March 8, 2024 Category: Cancer & Oncology Authors: Chang Gon Kim Min Hee Hong Dahee Kim Brian Hyohyoung Lee Hyunwook Kim Chan-Young Ock Geoffrey Kelly Yoon Ji Bang Gamin Kim Jung Eun Lee Chaeyeon Kim Se-Heon Kim Hyun Jun Hong Young Min Park Nam Suk Sim Heejung Park Jin Woo Park Chang Geol Lee Kyung Hwan K Source Type: research

A phase II open-label randomized clinical trial of preoperative durvalumab or durvalumab plus tremelimumab in resectable head and neck squamous cell carcinoma
CONCLUSIONS: Preoperative D+/-T is feasible and may benefit patients with resectable HNSCC. Distinct changes in the tumor microenvironment and circulating immune cells were induced by each treatment regimen, warranting further investigation.PMID:38457288 | DOI:10.1158/1078-0432.CCR-23-3249 (Source: Cell Research)
Source: Cell Research - March 8, 2024 Category: Cytology Authors: Chang Gon Kim Min Hee Hong Dahee Kim Brian Hyohyoung Lee Hyunwook Kim Chan-Young Ock Geoffrey Kelly Yoon Ji Bang Gamin Kim Jung Eun Lee Chaeyeon Kim Se-Heon Kim Hyun Jun Hong Young Min Park Nam Suk Sim Heejung Park Jin Woo Park Chang Geol Lee Kyung Hwan K Source Type: research

Genomic Testing to Guide Local Therapy Decisions in Hormone Receptor-Positive Breast Cancer
AbstractPurpose of ReviewTo explore how genomic testing has changed local therapy decision-making, specifically surgical timing and opportunities for de-escalation of radiation therapy in hormone receptor-positive, HER2-negative (HR + HER2-) breast cancer.Recent FindingsRandomized trials have shown that genomic tests can be used to guide systemic therapy decision in HR + HER2- breast cancer, with a significant proportion of patients not receiving benefit from chemotherapy. Emerging data suggests that the use of genomic testing on core needle biopsy can also predict response to preoperative therapy and guide choic...
Source: Current Breast Cancer Reports - March 7, 2024 Category: Cancer & Oncology Source Type: research

Inflammatory and Nutritional Biomarkers in Patients With Esophageal Squamous Cell Carcinoma Undergoing Neoadjuvant Chemotherapy and Radiation Therapy
Oncol Nurs Forum. 2024 Feb 19;51(2):177-192. doi: 10.1188/24.ONF.177-192.ABSTRACTOBJECTIVES: To investigate the relationship between pretreatment inflammatory and nutritional biomarkers in patients with esophageal squamous cell carcinoma (ESCC) undergoing neoadjuvant chemotherapy and radiation therapy (nCRT).SAMPLE & SETTING: 213 patients with newly diagnosed stage II-III ESCC who received nCRT at an academic hospital in Taiwan.METHODS & VARIABLES: Electronic health record data were used. Records on inflammatory and nutritional biomarkers and clinical outcomes were extracted. Logistic regression analysis was used t...
Source: Oncology Nursing Forum - March 5, 2024 Category: Nursing Authors: Chun Hou Huang Bee Song Chang Tai-Chu Peng Yun-Hsin Peng Source Type: research