Africa: Patients Across Four Continents Enrol in Multidrug-Resistant Tuberculosis Trial
[MSF] Hundreds of patient volunteers from four continents have enrolled in a trial that aims to find safer, shorter, and effective treatments for multidrug-resistant tuberculosis (MDR-TB), an airborne, infectious disease that has grown resistant to standard medications. A group of scientists and clinicians led by M édecins Sans Frontières (MSF), Partners In Health (PIH) and Interactive Research and Development (IRD) make up the endTB consortium conducting the groundbreaking study funded by Unitaid. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 19, 2021 Category: Infectious Diseases Source Type: news
Colonisation resistance against multidrug-resistant bacteria: a narrative review
Colonisation resistance by gut microbiota is a fundamental phenomenon in infection prevention and control. Hospitalised patients may be exposed to multidrug-resistant bacteria when hand hygiene compliance among healthcare workers is not adequate. An additional layer of defence is provided by the healthy gut microbiota, which helps clear the exogenous bacteria and acts as a safety net when hand hygiene procedures are not followed. This narrative review focuses on the gut microbiota ' s role in colonisation resistance against multidrug-resistant bacteria and its implications for infection control. We discuss the underlying m...
Source: Current Awareness Service for Health (CASH) - October 15, 2021 Category: Consumer Health News Source Type: news
Eritrea: Green Light Committee Monitoring Mission 2021
[WHO-AFRO] The Green Light Committee (GLC) Initiative, together with the Working Group on MDR-TB, promotes implementation of the component two of the Stop TB Strategy that calls for the control and prevention of multidrug-resistant tuberculosis (MDR-TB) through: (i) increased access to quality-assured second-line anti-TB drugs; and (ii) prevention of development of resistance to anti-TB drugs in accordance with the Global Plan to Stop TB (2006-2015) and the Global MDR/XDR-TB Response plan (2007-2008). (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - September 14, 2021 Category: Infectious Diseases Source Type: news
Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units
Infections with multidrug-resistant organisms among patients in intensive care units (ICUs) are associated with high mortality. Among multidrug-resistant organisms, carbapenem-resistant Enterobacterales (CRE) harbor important pathogens for healthcare-associated infections, including pneumonia, bacteremia, and urinary tract infections. Risk factors for CRE colonization include underlying comorbid conditions, prior antibiotics exposure, prior use of healthcare facilities, device use, and longer ICU stay. The mortality rate due to invasive CRE infection is 22%-49%, and CRE colonization is associated with an approximately 10-f...
Source: Current Awareness Service for Health (CASH) - September 9, 2021 Category: Consumer Health News Source Type: news
Rapid Intervention Can Contain Multidrug-Resistant Candida Auris
TUESDAY, Sept. 7, 2021 -- The multidrug-resistant yeast, Candida auris, can be identified and contained with enhanced laboratory surveillance and prompt investigation with infection prevention and control (IPC) support, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 7, 2021 Category: Pharmaceuticals Source Type: news
Infectious Disease Alert Updates
Sepsis Bundle Erodes Gains in Stewardship; Asymptomatic Transmission of COVID-19 in Households; When Is Hand Hygiene Personally Protective? Four different categories of antibiotic use were observed, including broad-spectrum antibiotics for community-acquired infection, broad-spectrum antibiotics for nosocomial infection/multidrug-resistant organisms, the use of anti-methicillin-resistant Staphylococcus aureus (MRSA) agents (such as vancomycin, daptomycin, linezolid, ceftaroline, etc.), as well as antibiotics for surgical prophylaxis. [...]a gap of up to 24 hours may occur before the physician picking up the case the next d...
Source: Current Awareness Service for Health (CASH) - August 12, 2021 Category: Consumer Health News Source Type: news
Shedding of methicillin-resistant Staphylococcus aureus and multidrug-resistant gram-negative bacilli during outpatient appointments and procedures outside hospital rooms
We examined shedding during appointments outside patient rooms. • 38.5% of MRSA-colonized patients shed MRSA during appointments. • Presence of wounds with MRSA was a significant risk for environmental shedding. • No shedding of multidrug-resistant gram-negative bacilli was detected. Limit ed information is available on the frequency of and risk factors for shedding of health care-associated pathogens in settings outside patient rooms. We conducted a cohort study of hospitalized or recently discharged patients with methicillin-resistant Staphylococcus aureus (MRSA) (N = 39) or multidr ug-resistant gram-negative bacil...
Source: Current Awareness Service for Health (CASH) - August 12, 2021 Category: Consumer Health News Source Type: news
Hand hygiene in health care: 20 years of ongoing advances and perspectives
Health-care-associated infections are the most prevalent adverse events of hospital care, posing a substantial threat to patient safety and burden on society. Hand hygiene with alcohol-based hand rub is the most effective preventive strategy to reduce health-care-associated infections. Over the past two decades, various interventions have been introduced and studied to improve hand hygiene compliance among health-care workers. The global implementation of the WHO multimodal hand hygiene improvement strategy and constant efforts to replace the use of soap and water with alcohol-based hand rub have led to a faster and more e...
Source: Current Awareness Service for Health (CASH) - August 12, 2021 Category: Consumer Health News Source Type: news
High-tech TOILETS could spread superbugs, study warns
Multidrug-resistant bacteria called Pseudomonas aeruginosa (MDRP) have been discovered on water jet nozzles on electric toilets in hospitals in Japan. (Source: the Mail online | Health)
Source: the Mail online | Health - July 12, 2021 Category: Consumer Health News Source Type: news
High-tech toilets could spread antibiotic-resistant superbugs in hospitals, Japanese study suggests
(European Society of Clinical Microbiology and Infectious Diseases) Water-jet nozzles in electric toilets--commonly used in Japan and other parts of Asia--may be reservoirs for multidrug-resistant Pseudomonas aeruginosa (MDRP) in hospitals, increasing the risk of dangerous germ transmission among patients, according to new research being presented at the European Congress of Clinical Microbiology& Infectious Diseases (ECCMID) held online this year. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 11, 2021 Category: International Medicine & Public Health Source Type: news
Johnson & Johnson Launches Network of Global Health Discovery Centers that Aim to Speed Up Science and Tackle Pandemic Threats
NEW BRUNSWICK, N.J., July 9, 2021 – Johnson & Johnson (the Company) today announced the launch of the J&J Centers for Global Health Discovery (J&J Centers), a new, global network of unique research partnerships that will leverage the institutional strengths of Johnson & Johnson and leading academic institutions to accelerate discovery research to address the world’s most pressing global health challenges. The first J&J Satellite Center for Global Health Discovery (Satellite Center) was launched at the London School of Hygiene & Tropical Medicine (LSHTM) at an event co-hosted by Johnson & Jo...
Source: Johnson and Johnson - July 9, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news
Africa: WHO Releases New Global Lists of High-Burden Countries for TB, HIV-Associated TB and Drug-Resistant TB
[WHO] The World Health Organization (WHO) today released updated global lists of high burden countries for tuberculosis (TB), HIV-associated TB and multidrug/rifampicin-resistant TB (MDR/RR-TB). The new lists are for 2021-2025 and replace those previously used between 2016 and 2020. (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - June 24, 2021 Category: Infectious Diseases Source Type: news
Is methicillin-resistant Staphylococcus aureus a common pathogen in ventilation-associated pneumonia?: The experience of a tertiary teaching hospital in Jordan
Abstract: Ventilator-associated pneumonia is a life threatening device related infection in intensive care units. Methicillin-resistant Staphylococcus aureus is considered a common contagious pathogen causing pneumonia and sepsis. To assess the prevalence of S aureus in comparison to other pathogens, and their antibacterial sensitivity profile in ventilator-associated pneumonia. Data regarding ventilator-associated pneumonia of adults admitted to the intensive care unit, at the Jordan University of Science and Technology Hospital, between 2012 and 2018 were extracted from the computerized system. Microorganisms and their s...
Source: Current Awareness Service for Health (CASH) - June 17, 2021 Category: Consumer Health News Source Type: news
Rapid Spread and Control of MDR Bacteria in COVID-19 Units Rapid Spread and Control of MDR Bacteria in COVID-19 Units
What factors may contribute to the spread of multidrug-resistant infections among hospitalized COVID-19 patients, and which infection control practices are most effective?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 6, 2021 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Tailor-made therapy of multi-resistant tuberculosis
(German Center for Infection Research) The successful treatment of multidrug-resistant tuberculosis requires clarification in advance as to which antibiotics the pathogens are resistant to. Classic testing is very time-consuming and delays the start of therapy. Researchers from the Research Center Borstel and the DZIF have now prepared a catalogue of all mutations in the genome of tuberculosis bacteria and on the basis of a genome sequencing can quickly and cheaply predict which medicines are most effective for tuberculosis treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 3, 2021 Category: International Medicine & Public Health Source Type: news
