Effectiveness of non-surgical interventions to improve health and well-being in women living with Mayer-Rokitansky-Kuster-Hauser syndrome: A systematic review
CONCLUSIONS: Clearly, vaginal dilation is a viable initial treatment option for women with MRKH syndrome. There is limited evidence that 'coital dilation' is an effective method of dilation for vaginal agenesis. The literature, however, supports the need for psychological intervention to improve health and well-being.IMPACT: Women with MRKH syndrome who require dilation can receive guidance and support from their healthcare providers, particularly sexual and reproductive health nurses, clinical nurse specialists and gynaecologists. From the point of diagnosis, clinical psychologists should be involved. As much as feasible,...
Source: Adv Data - November 23, 2023 Category: Epidemiology Authors: Anu Baby Manju C Pallam Mark Hayter Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Antibiofilm potential of gallic acid against < em > Klebsiella pneumoniae < /em > and < em > Enterobacter hormaechei < /em > : < em > in-vitro < /em > and < em > in-silico < /em > analysis
This study aimed to assess the anti-biofilm activity of gallic acid (GA) against E. hormaechei and K. pneumoniae. The results of biofilm quantification assays demonstrated that GA exhibited significant antibiofilm activity against E. hormaechei and K. pneumoniae at concentrations of 4 mg mL-1, 2 mg mL-1, 1 mg mL-1, and 0.5 mg mL-1. Similarly, GA exhibited a dose-dependent reduction in violacein production, a QS-regulated purple pigment, indicating its ability to suppress violacein production and disrupt QS mechanisms in Chromobacterium violaceum. Additionally, computational tools were utilized to identify the potential tar...
Source: Biofouling - November 17, 2023 Category: Molecular Biology Authors: Pooja P Rajan Praveen Kumar Minsa Mini Devi Jayakumar Parvathi Vaikkathillam Sneha Asha Aparna Mohan Manjusree S Source Type: research

Alternative Biological Material for Tissue Engineering of the Vagina: Porcine-Derived Acellular Vaginal Matrix
Conclusion:This study reveals that porcine-derived AVM has potential application for vaginal regeneration. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - November 10, 2023 Category: Biotechnology Source Type: research

Sexual function and gynecologic surgery: where do we go from here?
Physical intimacy and procreation are some of the most innately human desires, and conditions that negatively impact sexual function and fertility often exact a toll on mental health, self-image, relationships, and general life course trajectory. Mayer-Rokitansky-K üster-Hauser (MRKH) is a rare congental condition characterized by agenesis of the Mullerian ducts in karotypic females (46, XX). Patients with MRKH typically present with variable degrees of uterovaginal agenesis, most commonly absent upper two-thirds of the vagina and absent or underdeveloped ute rus. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - November 10, 2023 Category: OBGYN Authors: Sara R. Till Tags: Editorial Source Type: research

Three-year follow-up results of two children born from a transplanted uterus
CONCLUSION: Though pregnancy after uterus transplantation is associated with the risk of premature delivery, no abnormalities were observed in the neonatal course and 3-year follow-up results, including the neurodevelopmental status, of two children born prematurely to mothers with a transplanted uterus. This is the first report on neurodevelopmental outcomes in children born after uterus transplantation. More data on children born after this radical procedure of uterine factor infertility treatment are required to support our promising results.PMID:37901926 | DOI:10.5507/bp.2023.042 (Source: Biomedical Papers of the Medic...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - October 30, 2023 Category: Biomedical Science Authors: Jan Janota Ekaterina Orlova Marta Novackova Roman Chmel Radim Brabec Zlatko Pastor Roman Chmel Source Type: research

10300 Robotic Vaginoplasty in MRKH Patient
Robotic Vaginoplasty. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 27, 2023 Category: OBGYN Authors: S Puntambekar, M Patil, A Puntambekar, S Puntambekar Source Type: research

10265 To Compare Efficacy of Vaginal Versus Laparoscopic Peritoneal Vaginoplasty in Women with MRKH Syndrome
To compare the efficacy of vaginal (McIndoe's) and laparoscopic peritoneal (Davydov's) vaginoplasty to create neovagina in MRKH patients. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 27, 2023 Category: OBGYN Authors: G Kachhawa, M Deoghare, R Mahey, JB Sharma, N Bhatla Source Type: research