Novel Minimally Invasive Technique of Neovaginoplasty Using An Absorbable Adhesion Barrier
The objective was to provide a minimally invasive neovaginoplasty technique to construct a nearly physiological vagina to facilitate sexual functioning and appropriate vaginal length in patients with congenital vaginal agenesis. This is a retrospective study at a tertiary care hospital. 52 patients with congenital vaginal agenesis owing to Mayer-Rokitansky-Küster-Hauser syndrome or androgen insensitivity syndrome presented for vaginal reconstruction. Modified McIndoe vaginoplasty was done in all patients between 2010 and 2018using a vaginal mold created with glove, nonadherent petroleum gauze, and Interceed absorbable...
Source: Journal of Minimally Invasive Gynecology - June 20, 2019 Category: OBGYN Source Type: research

Novel Minimally Invasive Technique of Neovaginoplasty Using An Absorbable Adhesion Barrier
The objective was to provide a minimally invasive neovaginoplasty technique to construct a nearly physiological vagina to facilitate sexual functioning and appropriate vaginal length in patients with congenital vaginal agenesis. This is a retrospective study at a tertiary care hospital. 52 patients with congenital vaginal agenesis owing to Mayer-Rokitansky-K üster-Hauser syndrome or androgen insensitivity syndrome presented for vaginal reconstruction. Modified McIndoe vaginoplasty was done in all patients between 2010 and 2018using a vaginal mold created with glove, nonadherent petroleum gauze, and Interceed absorbabl...
Source: The Journal of Minimally Invasive Gynecology - June 19, 2019 Category: OBGYN Authors: Manjula Anagani, Prabha Agrawal, Krishnakumari Meka, Rashmi Thippasandra Narayana, Radhika Bandameedipally Tags: Instruments and Techniques Source Type: research

Ovarian Teratomas in Women With Anti-N-methyl-D-Aspartate Receptor Encephalitis: Topography and Composition of Immune Cell and Neuroglial Populations Is Compatible With an Autoimmune Mechanism of Disease
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune syndrome in young women that is often accompanied by an ovarian teratoma (NMDAR-E teratoma). A prevailing theory implicates that the generation of autoantibodies to NMDAR on neurons in the central nervous system is triggered by neuroglial tissue in the associated teratoma. The histopathology of NMDAR-E teratomas has not been fully elucidated but limited studies have focused on alterations in neuroglial tissues and immune cell populations. We hypothesized that evidence of antibody generation in NMDAR-E teratomas could be detected by colocalized neurogl...
Source: The American Journal of Surgical Pathology - June 13, 2019 Category: Pathology Tags: Original Articles Source Type: research

A Rare Cause of Postprandial Pain
​BY DHIMITRI A. NIKOLLA, DO; BRENDAN A. MICCIO; MELODY L. MILLIRON; & BRETT FOREHAND, MD, PHDA 49-year-old woman with a past medical history of chronic obstructive pulmonary disease presented to the emergency department with epigastric pain. She said the pain radiated to her chest and had been intermittent for six months, but it had been progressively worsening over the previous three weeks. Her pain was exacerbated by eating, and was associated with early satiety and nausea. She complained of a 30-pound weight loss over the preceding three months.Her vital signs included a blood pressure of 116/80 mm Hg, a heart rat...
Source: The Case Files - June 12, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Oocyte Retrieval During Laparoscopic Vaginoplasty to Reduce Invasiveness in the Treatment of Mayer-Rokitansky Küster-Hauser Syndrome
ConclusionThis is the first report of combined oocyte retrieval and vaginoplasty for patients with MRKH syndrome. The approach was found to be feasible in patients with a desire for future fertility. It is our belief that physicians treating patients with MRKH should refer patients to centers with expertise in both vaginoplasty and assisted reproductive technology. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - May 25, 2019 Category: OBGYN Source Type: research

Oocyte Retrieval During Laparoscopic Vaginoplasty to Reduce Invasiveness in the Treatment of Mayer-Rokitansky K üster-Hauser Syndrome
To evaluate the treatment of patients with Mayer-Rokitansky K üster-Hauser (MRKH) syndrome with a combination of oocyte retrieval and surgical vaginoplasty in a single laparoscopic procedure. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - May 23, 2019 Category: OBGYN Authors: Massimo Candiani, Valeria S. Vanni, Enrico Papaleo, Diana Delprato, Iacopo Tandoi, Valeria Gervasio, Marta Parma, Laura Corti, Serena Girardelli, Luigi Fedele Tags: Original Article Source Type: research

Lipid profiles in women with Mayer-Rokitansky-Kuster-Hauser syndrome.
Authors: Zhao L, Shan J, Zhou Y, Zhao Y, Jin H, Xie Z Abstract PMID: 31089085 [PubMed - as supplied by publisher] (Source: Panminerva Medica)
Source: Panminerva Medica - May 17, 2019 Category: General Medicine Tags: Panminerva Med Source Type: research

Tilapia fish skin as a new biologic graft for neovaginoplasty in Mayer-Rokitansky-Kuster-Hauser syndrome: a video case report
To describe a McIndoe procedure technique for surgical management of Mayer-Rokitansky-Kuster-Hauser syndrome with the use of Nile tilapia skin as a scaffold for the proliferation of new vaginal epithelium. (Source: Fertility and Sterility)
Source: Fertility and Sterility - May 15, 2019 Category: Reproduction Medicine Authors: Maria Tereza Pinto Medeiros Dias, Edmar Maciel Lima J únior, Ana Paula Negreiros Nunes Alves, Andreisa Paiva Monteiro Bilhar, Livia Cunha Rios, Bruno Almeida Costa, Eduarda Syhara Rocha Matos, Ana Cecília Venancio, Zenilda Vieira Bruno, Manoel Odorico d Tags: Video Source Type: research

Livebirth After Uterus Transplantation From a Deceased Donor in a Recipient With Uterine Infertility
(Abstracted from Lancet 2018;392:2697–2704) Infertility is common and affects about 10% to 15% of couples. In such couples, 1 in 500 women has infertility due to uterine causes, with uterine agenesis (Mayer-Rokitansky-Küster-Hauser [MRKH] syndrome), or due to hysterectomy, malformation, or the sequelae of infection or surgery. (Source: Obstetrical and Gynecological Survey)
Source: Obstetrical and Gynecological Survey - May 1, 2019 Category: OBGYN Tags: OBSTETRICS: ETHICS, MEDICOLEGAL ISSUES, AND PUBLIC POLICY Source Type: research

Novel Anastomotic Technique for Uterine Transplant Using Utero-ovarian Veins for Venous Drainage and Internal Iliac Arteries for Perfusion in Two Laparoscopically Harvested Uteri
Publication date: May–June 2019Source: Journal of Minimally Invasive Gynecology, Volume 26, Issue 4Author(s): Shailesh Puntambekar, Seema Puntambekar, Milind Telang, Pankaj Kulkarni, Shardul Date, Mangesh Panse, Ravindra Sathe, Nikhil Agarkhedkar, Neeta Warty, Sandesh Kade, Manoj Manchekar, Mihir Chitale, Hirav Parekh, Kajal Parikh, Mehul Mehta, Bhushan Kinholkar, Joy Shankar Jana, Avinash Pare, Shailendra Kanade, Abhay SadreAbstractStudy ObjectiveTo evaluate 2 cases of uterine transplant surgery that used utero-ovarian veins as outflow channels, internal iliac arteries for perfusion, and the organ harvest surgery pe...
Source: Journal of Minimally Invasive Gynecology - April 25, 2019 Category: OBGYN Source Type: research

Treatment guidelines for persistent cloaca, cloacal exstrophy, and Mayer –Rokitansky–Küster–Häuser syndrome for the appropriate transitional care of patients
AbstractWe developed treatment guidelines (TGs) for appropriate transitional care of the genitourinary system in patients with persistent cloaca (PC), cloacal exstrophy (CE), or Mayer –Rokitansky–Küster–Häuser syndrome (MRKH). These TGs are in accordance with the Medical Information Network Distribution Service (Minds), published in 2014 in Japan. Clinical questions (CQs) concerning treatment outcomes of the genitourinary system, pregnancy and delivery, and quality of lif e in adulthood were prepared as six themes for PC and CE and five themes for MRKH. We were able to publish statements on chro...
Source: Surgery Today - April 22, 2019 Category: Surgery Source Type: research

Urogynecological and Sexual Functions after Vecchietti Reconstructive Surgery.
Conclusion: Quality of sexual life after the Vecchietti's operation in long-term follow-up does not differ from that of healthy women, but these patients suffer more frequent from urogynecological complaints. The trial is registered with NCT03809819. PMID: 30931323 [PubMed - in process] (Source: Biomed Res)
Source: Biomed Res - April 3, 2019 Category: Research Authors: Adamiak-Godlewska A, Skorupska K, Rechberger T, Romanek-Piva K, Miotła P Tags: Biomed Res Int Source Type: research

Co-occurrence of Mayer-Rokitansky-Küster-Hauser syndrome and ovarian cancer: A case report and review of the literature
Publication date: Available online 17 March 2019Source: Gynecologic Oncology ReportsAuthor(s): Roberta Villa, Jacopo Azzollini, Bernard Peissel, Siranoush ManoukianAbstractBackgroundMayer-Rokitansky-Kuster-Hauser syndrome (MRKHS) is a congenital disorder of yet unknown etiology, characterized by agenesis/hypoplasia of the müllerian duct system. The occurrence of ovarian cancer (OC) in MRKHS is rare, with
Source: Gynecologic Oncology Reports - March 18, 2019 Category: OBGYN Source Type: research

MRI evaluation of pelvis in Mayer-Rokitansky-Kuster-Hauser syndrome: interobserver agreement for surgically relevant structures.
CONCLUSION:: MRI is capable of providing key pre-operative anatomical information in MRKH syndrome non-invasively. There is good to excellent interobserver agreement for MRI features of most of the surgical relevant structures. ADVANCES IN KNOWLEDGE:: MRI features of salient preoperative anatomical structures are reproducible between observers. PMID: 30864823 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - March 13, 2019 Category: Radiology Authors: Bhayana A, Ghasi RG Tags: Br J Radiol Source Type: research

Tissue-engineered solution containing cells and biomaterials-an in vitro study: A perspective as a novel therapeutic application.
This study tested the efficiency of tissue-engineered solution containing human malignant melanoma cell line (HMV-II) and different biomaterials, including Cellprene®, Membracel®, and poly lactic-co-glycolic acid/epoxidized polyisoprene. The cells adhered better on poly lactic-co-glycolic acid/epoxidized polyisoprene, and it was found that tissue-engineered solution may also contain mesenchymal stem cells cultivated on poly lactic-co-glycolic acid/epoxidized polyisoprene. Histological, immunofluorescence, and scanning electron microscopy analyses were performed. These initial in vitro results suggest that tissue-en...
Source: The International Journal of Artificial Organs - March 6, 2019 Category: Transplant Surgery Authors: Henckes NAC, Festa JCD, Faleiro D, Medeiros HR, Guerra NB, Dos Santos LAL, Terraciano PB, Passos EP, de Oliveira FDS, Cirne-Lima EO Tags: Int J Artif Organs Source Type: research

2. A Research Agenda for Mayer-Rokitansky-K üster-Hauser Syndrome
Mayer-Rokitansky-K üster-Hauser (MRKH) Syndrome is a congenital birth defect characterized by absence or incomplete development of the Müllerian-derived tissues of the female reproductive tract that is associated with renal, skeletal, cardiac, spine and ear anomalies. Affected Individuals often experience isolation, loneliness, shock and depression and MRKH can affect self-esteem and increase the risk of eating disorders and phobic anxieties. In 2017, we conducted an online anonymous survey of 1337 patients, parents, partners and providers on their experiences with MRKH through diagnosis and treatment, to bett er...
Source: Journal of Pediatric and Adolescent Gynecology - March 4, 2019 Category: OBGYN Authors: Amy C. Lossie, Alison Hensley, Kristiiana Siiankoski, Kristy Zieman, Susan Carroll, Anne-Marie Amies Oelschlager, Elisabeth H. Quint, Veronica Gomez-Lobo, Marc Laufer, Diane F. Merritt Source Type: research

Individual approach at the treatment of vaginal aplasia in adolescents by using the physiotherapy techniques
Introduction: Aplasia of the vagina and uterus is found 1 times in the 4000 –5000 newborn girls. From all cases of aplasia 90% takes syndrome Rokitansky-Kuster-Hauser-Mayer. The main complaint of patients is the absence of menstruation and inability in sexual life. The first line of therapy is vaginal dilation. Aplasia of the vagina – a pathology that not endangered for life, but causes psychological, social and reproductive difficulties that's why it is necessary to modernize the classical treatment to improve the quality of medical care and its effectiveness. (Source: European Journal of Obstetrics, Gynecolog...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2019 Category: OBGYN Authors: Natalya Buralkina, M.v. Ipatova, Zalina K. Batyrova, D.A. Kruglyak, E.v. Uvarova Tags: Session 31 – Paediatric and Adolescent Gynaecology Source Type: research

Sequence Variants in TBX6 Are Associated with Disorders of the M üllerian Ducts: An Update
M üllerian anomalies comprise the Mayer-Rokitansky-Küster-Hauser syndrome as well as fusion defects of the müllerian ducts. Recurrent micro-aberrations like deletions in 16p11.2 encompassingTBX6 were found to be causative in these patients.TBX6 encodes a transcription factor which plays a role in paraxial mesoderm differentiation/specification. In previous studies, we and other groups found possibly pathogenic variants inTBX6 in patients with m üllerian anomalies. Since we suggestedTBX6 as a strong candidate, we performed sequential analysis of theTBX6gene in additional 125 patients with m üllerian...
Source: Sexual Development - February 12, 2019 Category: Biology Source Type: research

Sequence Variants in TBX6 Are Associated with Disorders of the M üllerian Ducts: An Update.
Sequence Variants in TBX6 Are Associated with Disorders of the Müllerian Ducts: An Update. Sex Dev. 2019 Feb 09;: Authors: Tewes AC, Hucke J, Römer T, Kapczuk K, Schippert C, Hillemanns P, Wieacker P, Ledig S Abstract Müllerian anomalies comprise the Mayer-Rokitansky-Küster-Hauser syndrome as well as fusion defects of the müllerian ducts. Recurrent micro-aberrations like deletions in 16p11.2 encompassing TBX6 were found to be causative in these patients. TBX6 encodes a transcription factor which plays a role in paraxial mesoderm differentiation/specification. In previous studi...
Source: Sexual Development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - February 9, 2019 Category: Genetics & Stem Cells Authors: Tewes AC, Hucke J, Römer T, Kapczuk K, Schippert C, Hillemanns P, Wieacker P, Ledig S Tags: Sex Dev Source Type: research

Sequence Variants in < b > < i > TBX6 < /i > < /b > Are Associated with Disorders of the M üllerian Ducts: An Update
M üllerian anomalies comprise the Mayer-Rokitansky-Küster-Hauser syndrome as well as fusion defects of the müllerian ducts. Recurrent micro-aberrations like deletions in 16p11.2 encompassingTBX6 were found to be causative in these patients.TBX6 encodes a transcription factor which plays a role in paraxial mesoderm differentiation/specification. In previous studies, we and other groups found possibly pathogenic variants inTBX6 in patients with m üllerian anomalies. Since we suggestedTBX6 as a strong candidate, we performed sequential analysis of theTBX6gene in additional 125 patients with m üllerian...
Source: Sexual Development - February 8, 2019 Category: Biology Source Type: research

Advancements in uterus transplant: new scenarios and future implications.
Authors: Zaami S, Di Luca A, Marinelli E Abstract Women suffering from Uterine Factor Infertility (UFI) arising from congenital conditions (e.g., Rokitansky-Kuster-Hauser syndrome) or hysterectomy can fulfill their wish to achieve motherhood only by resorting to surrogacy, which is, however, banned in most countries. Medical research has long been looking into uterus transplant (UTx), which may constitute a valuable alternative for such patients. Following decades of animal testing and clinical trials, several successful pregnancies have been carried to term. Yet UTx is still to be considered as an experimental pro...
Source: European Review for Medical and Pharmacological Sciences - February 6, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Surgery Is Not Superior to Dilation for the Management of Vaginal Agenesis in Mayer-Rokitansky-Küster-Hauser Syndrome: A Multicenter Comparative Observational Study in 131 Patients
(Abstracted from Am J Obstet Gynecol 2018;219:281.e1–281.e9) Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital condition characterized by vaginal agenesis, which impairs sexuality and has a negative impact on quality of life (QOL). Classic management of this condition is to create a cavity allowing satisfying painless penetrative intercourse. (Source: Obstetrical and Gynecological Survey)
Source: Obstetrical and Gynecological Survey - February 1, 2019 Category: OBGYN Tags: GYNECOLOGY: UROGYNECOLOGY Source Type: research

Sexual satisfaction in patients with Mayer-Rokitansky-K üster-Hauser syndrome after surgical and non-surgical techniques: a systematic review
ConclusionThe reviewed studies highlighted the need for further quantitative and qualitative research on the sexual performance and outcomes of patients with MRKH syndrome.Registration numberNone. (Source: International Urogynecology Journal)
Source: International Urogynecology Journal - January 5, 2019 Category: OBGYN Source Type: research

A Novel Anastomotic Technique for Uterine Transplant Using Utero-ovarian Veins for Venous Drainage and Internal Iliac Arteries for Perfusion in Two Laparoscopically Harvested Uteri
Publication date: Available online 29 December 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): Shailesh Puntambekar, Seema Puntambekar, Milind Telang, Pankaj Kulkarni, Shardul Date, Mangesh Panse, Ravindra Sathe, Nikhil Agarkhedkar, Neeta Warty, Sandesh Kade, Manoj Manchekar, Mihir Chitale, Hirav Parekh, Kajal Parikh, Mehul Mehta, Bhushan Kinholkar, Joy Shankar Jana, Avinash Pare, Shailendra Kanade, Abhay SadreABSTRACTStudy objectiveTo evaluate 2 cases of uterine transplant surgery that used utero-ovarian veins as outflow channels, internal iliac arteries for perfusion, and the organ harvest surgery being pe...
Source: Journal of Minimally Invasive Gynecology - December 30, 2018 Category: OBGYN Source Type: research

Uterus transplantation and fertility preservation
Publication date: Available online 21 December 2018Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Mats Brännström, Pernilla Dahm-KählerAbstractAbsolute uterine factor infertility (AUFI), with uterine absence or presence of a non-functional uterus, was considered untreatable until 2014, when the first child was born after transplantation of a uterus from a postmenopausal woman to a woman of fertile age who was born with no uterus, as part of the MRKH syndrome. Concerning gynaecological cancer, AUFI may occur after hysterectomy for malignancy or after surgery/radiation tha...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - December 21, 2018 Category: OBGYN Source Type: research

Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility
We describe, to our knowledge, the first case worldwide of livebirth following uterine transplantation from a deceased donor in a patient with MRKH syndrome. The results establish proof-of-concept for treating uterine infertility by transplantation from a deceased donor, opening a path to healthy pregnancy for all women with uterine factor infertility, without need of living donors or live donor surgery.FundingFundação de Amparo à Pesquisa do Estado de São Paulo and Hospital das Clínicas, University of São Paulo, Brazil. (Source: The Lancet)
Source: The Lancet - December 5, 2018 Category: General Medicine Source Type: research

Sexual Response in Women With Mayer-Rokitansky-Küster-Hauser Syndrome With a Nonsurgical Neovagina
(Abstracted from Am J Obstet Gynecol 2018;219:283.e1–283.e8) Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is an uncommon congenital condition characterized by an agenesis or hypoplasia of vagina and uterus. The first-line treatment approach—nononsurgical vaginal elongation by dilation—has high success rates (90%–96%). (Source: Obstetrical and Gynecological Survey)
Source: Obstetrical and Gynecological Survey - December 1, 2018 Category: OBGYN Tags: GYNECOLOGY: NORMAL AND ABNORMAL SEXUAL DEVELOPMENT Source Type: research

Identification of Candidate Genes for Mayer-Rokitansky-K üster-Hauser Syndrome Using Genomic Approaches.
Identification of Candidate Genes for Mayer-Rokitansky-Küster-Hauser Syndrome Using Genomic Approaches. Sex Dev. 2018 Dec 01;: Authors: Backhouse B, Hanna C, Robevska G, van den Bergen J, Pelosi E, Simons C, Koopman P, Juniarto AZ, Grover S, Faradz S, Sinclair A, Ayers K, Tan TY Abstract Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a disorder of sex development which affects 1 in 4,500 females and is characterized by agenesis of müllerian structures, including the uterus, cervix, and upper vagina. It can occur in isolation (type 1) or in conjunction with various anomalies (type 2),...
Source: Sexual Development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - December 1, 2018 Category: Genetics & Stem Cells Authors: Backhouse B, Hanna C, Robevska G, van den Bergen J, Pelosi E, Simons C, Koopman P, Juniarto AZ, Grover S, Faradz S, Sinclair A, Ayers K, Tan TY Tags: Sex Dev Source Type: research

Identification of Candidate Genes for Mayer-Rokitansky-K üster-Hauser Syndrome Using Genomic Approaches
Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome is a disorder of sex development which affects 1 in 4,500 females and is characterized by agenesis of müllerian structures, including the uterus, cervix, and upper vagina. It can occur in isolation (type 1) or in conjunction with various anomalies (type 2), with a subs et of these comprising müllerian, renal, and cervicothoracic abnormalities (MURCS) association. The genetic causes of MRKH have been investigated previously yielding limited results, with massive parallel sequencing becoming increasingly utilized. We sought to identify genetic contributions to MR...
Source: Sexual Development - November 30, 2018 Category: Biology Source Type: research

M üllerian aplasia with severe hematometra: A case report of diagnosis and management in a low resource setting
M üllerian aplasia or Mayer-Rokitansky-Küster-Hauser syndrome is described as congenital absence of the proximal vagina with or without absence of the cervix and uterus, most often recognized following the onset of primary amenorrhea. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - November 21, 2018 Category: OBGYN Authors: Lucille A. Howard, Abigail C. Mancuso, Ginny L. Ryan Source Type: research

Vaginoplasty Using Human Amniotic Membranes A Report of Five Patients.
CONCLUSION: McIndoe vaginoplasty is a simple, safe, and quick operative method that results in a ftnctional vagina. The amnion is a suitable material to apply to the surface of the neovagina because it is readily avail- able and does not have any associated immune reiection problems or costs. PMID: 30383949 [PubMed] (Source: Journal of Reproductive Medicine)
Source: Journal of Reproductive Medicine - November 3, 2018 Category: Reproduction Medicine Tags: J Reprod Med Source Type: research

691 - Combined Laparoscopic and Vaginal Cervicovaginal Reconstruction Using Acellular Porcine Sis Graft in a Patient with Mrkh Syndrome (u5ac4v4)
Publication date: November–December 2018Source: Journal of Minimally Invasive Gynecology, Volume 25, Issue 7, SupplementAuthor(s): X. Zhang, K. Hua, Y. Ding, S. Liu, N. Jia (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - October 22, 2018 Category: OBGYN Source Type: research

673 - To Demonstrate Method of Laparoscopic Creation of Neo Vagina by Peritoneal Pull Through Technique in Case of MRKH
Publication date: November–December 2018Source: Journal of Minimally Invasive Gynecology, Volume 25, Issue 7, SupplementAuthor(s): S. Saini (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - October 22, 2018 Category: OBGYN Source Type: research

Anatomic and Functional Outcomes of Laparoscopic Peritoneal Vaginoplasty (Luohu II Procedure) in Patients with MRKH Syndrome: 9 Years of Experience with 823 Patients
Objective: To assess anatomical and functional outcomes of a novel laparoscopic peritoneal vaginoplasty technique (Luohu II procedure) in patients with Mayer-Rokitansky-K üster-Hauser syndrome (MRKHS). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 22, 2018 Category: OBGYN Authors: H. Pan, G. Luo Source Type: research

Combined Laparoscopic and Vaginal Cervicovaginal Reconstruction Using Acellular Porcine Sis Graft in a Patient with Mrkh Syndrome (u5ac4v4)
Objective: To introduce a creation that combines laparoscopic and Wharton-Sheares-George cervicovaginal reconstruction using SIS graft in a patient with Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome who had a rudimentary cavity (U5aC4V4). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 22, 2018 Category: OBGYN Authors: X. Zhang, K. Hua, Y. Ding, S. Liu, N. Jia Source Type: research

To Demonstrate Method of Laparoscopic Creation of Neo Vagina by Peritoneal Pull Through Technique in Case of MRKH
Objective: To demonstrate a method of laparoscopic creation of neo vagina by peritoneal pull through technique in case of MRKH. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 22, 2018 Category: OBGYN Authors: S. Saini Source Type: research

Addressing the Difficulties in Neovaginoplasty by a New Solapur Technique
Objective: MRKH syndrome has absent or underdeveloped uterus and vagina. It affects 1 in every 5000 females. The medical world has been trying to find answers to the creation of the neo-vagina for a long time. The existing surgical techniques have 3 common hurdles: 1. Blind or compromised creation of neo vagina risking the bladder and rectum; 2. Find the ideal tissue to line the vagina; 3. Preventing the post surgical contracture of the neo-vagina. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 22, 2018 Category: OBGYN Authors: S. Kade Source Type: research

A rare case of Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome with solitary ectopic pelvic kidney and uretropelvic junction (UPJ) obstruction
Publication date: Available online 22 September 2018Source: Urology Case ReportsAuthor(s): Saleh Bubishate, Iqbal Saleh, Rami M. Hasan (Source: Urology Case Reports)
Source: Urology Case Reports - September 22, 2018 Category: Urology & Nephrology Source Type: research

Treatment of vaginal agenesis in Mayer-Rokitansky-K üster-Hauser syndrome in Denmark: a nationwide comparative study of anatomical outcome and complications
To compare the long-term anatomical outcome and complications in treatments of vaginal agenesis in Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2018 Category: Reproduction Medicine Authors: Morten Herlin, Anne-Mette Bay Bj ørn, Laura Krogh Jørgensen, Birgitta Trolle, Michael Bjørn Petersen Tags: Original article Source Type: research

Mayer-Rokitansky-Küster-Hauser Syndrome With Bilateral Ovarian Sertoli Cell Tumors: Review of the Literature and Report of a Rare Case
Conclusions The case presented is unique in that 2 rare pathologies, bilateral Sertoli cell tumors of the ovary and MRKH syndrome, developed concomitantly in the same patient. (Source: Journal of Pelvic Medicine and Surgery)
Source: Journal of Pelvic Medicine and Surgery - August 28, 2018 Category: Surgery Tags: Case Reports Source Type: research

Spectrum of Type I and Type II syndromes and associated malformations in Chinese patients with Mayer-Rokitansky-K üster-Hauser syndrome: A retrospective analysis of 274 cases
To analyze the spectrum of Type I and Type II malformations in Chinese patients with Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - August 13, 2018 Category: OBGYN Authors: Shan Deng, Yonglan He, Na Chen, Lan Zhu Source Type: research

Surgery is Not Superior to Dilation for the Management of Vaginal Agenesis in MRKH Syndrome: A Multicenter Comparative Observational Study in 131 Patients
Vaginal agenesis in Mayer-Rokitanski-K üster-Hauser (MRKH) syndrome can be managed either by various surgeries or dilation. The choice still depends on surgeon’s preferences rather than on quality comparative studies and validated protocols. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2018 Category: OBGYN Authors: Alaa Cheikhelard, Maud Bidet, Amandine Baptiste, Magali Viaud, Christine Fagot, Naziha Khen-Dunlop, Christine Louis-Sylvestre, The French MRKH Study-Group, Sabine Sarnacki, Philippe Touraine, Caroline Elie, Yves Aigrain, Michel Polak Source Type: research

Surgery is not superior to dilation for the management of vaginal agenesis in Mayer-Rokitansky-K üster-Hauser syndrome: a multicenter comparative observational study in 131 patients
Vaginal agenesis in Mayer-Rokitansky-K üster-Hauser syndrome can be managed either by various surgeries or dilation. The choice still depends on surgeon’s preferences rather than on quality comparative studies and validated protocols. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2018 Category: OBGYN Authors: Alaa Cheikhelard, Maud Bidet, Amandine Baptiste, Magali Viaud, Christine Fagot, Naziha Khen-Dunlop, Christine Louis-Sylvestre, Sabine Sarnacki, Philippe Touraine, Caroline Elie, Yves Aigrain, Michel Polak, French MRKH Study Group Tags: Original Research Source Type: research

Sexual response in women with Mayer-Rokitansky-K üster-Hauser syndrome with a non-surgical neo-vagina
Comparison of vaginal blood flow and subjective sexual response in women with Mayer-Rokitansky-K üster-Hauser syndrome and a non-surgical neo-vagina with controls. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 12, 2018 Category: OBGYN Authors: Stephanie Both, Kirsten Kluivers, Marianne Ten Kate-Booij, Philomeen Weijenborg Tags: Original Research: Gynecology Source Type: research

Sexual response in women with Mayer-Rokitansky-K üster-Hauser syndrome with a nonsurgical neovagina
Sexual dysfunction is prevalent in women with Mayer-Rokitansky-K üster-Hauser syndrome after the creation of a neovagina. Insight into the physiologic response of the neovagina during sexual arousal is lacking, although this would help in the understanding of sexual function of these patients. The physiologic sexual response of the vagina can be measured objecti vely by vaginal photoplethysmography to assess vaginal blood flow. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 12, 2018 Category: OBGYN Authors: Stephanie Both, Kirsten Kluivers, Marianne ten Kate-Booij, Philomeen Weijenborg Tags: Original Research Source Type: research

Combined laparoscopic and vaginal cervicovaginal reconstruction using acellular porcine small intestinal submucosa (SIS) graft in a patient with Mayer-Rokitansky-Küster-Hauser syndrome (U5aC4V4)
CONCLUSION(S)In the past, the uterus with a rudimentary cavity of the MRKH patients was always excised. And the patients lost the chance of menstrual onset and fertility. Combined laparoscopic and Wharton-Sheares-George cervicovaginal reconstruction using SIS graft provided a minimally invasive, safe, and effective surgical option for the young patient with MRKH syndrome with a rudimentary cavity. The technique is not complex and easy to learn and perform. And it provided a result with functional and anatomical satisfaction. No special surgical apparatus is needed. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - July 11, 2018 Category: OBGYN Source Type: research

Vaginal prevalence of HPV infections in uterovaginal aplasia patients before and after laparoscopically assisted creation of a neovagina: a prospective epidemiological observational study.
CONCLUSIONS: Vaginal HPV prevalence and HPV types in previously virgin patients after creation of a neovagina is not different from the acquisition of cervical infections in the general population and is clearly associated with sexual activity and with smoking habits. However, abnormal Pap smears are however rarely seen. This article is protected by copyright. All rights reserved. PMID: 29992731 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - July 10, 2018 Category: OBGYN Authors: Rall KK, Schoenfisch B, Schoeller D, Stefanescu D, Koelle A, Henes M, Huebner M, Taran FA, Seeger H, Iftner A, Iftner T, Brucker SY Tags: BJOG Source Type: research

Combined laparoscopic and vaginal cervicovaginal reconstruction using acellular porcine small intestinal submucosa (SIS) graft in a patient with Mayer-Rokitansky-Küster-Hauser syndrome (U5aC4V4)
CONCLUSION(S)In the past, the uterus with a rudimentary cavity of the MRKH patients was always excised. And the patients lost the chance of menstrual onset and fertility. Combined laparoscopic and Wharton-Sheares-George cervicovaginal reconstruction using SIS graft provided a minimally invasive, safe, and effective surgical option for the young patient with MRKH syndrome with a rudimentary cavity. The technique is not complex and easy to learn and perform. And it provided a result with functional and anatomical satisfaction. No special surgical apparatus is needed. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - July 5, 2018 Category: OBGYN Source Type: research

Combined laparoscopic and vaginal cervicovaginal reconstruction using acellular porcine small intestinal submucosa (SIS) graft in a patient with Mayer-Rokitansky-K üster-Hauser syndrome (U5aC4V4)
CONCLUSION(S) In the past, the uterus with a rudimentary cavity of the MRKH patients was always excised. And the patients lost the chance of menstrual onset and fertility. Combined laparoscopic and Wharton-Sheares-George cervicovaginal reconstruction using SIS graft provided a minimally invasive, safe, and effective surgical option for the young patient with MRKH syndrome with a rudimentary cavity. The technique is not complex and easy to learn and perform. And it provided a result with functional and anatomical satisfaction. No special surgical apparatus is needed. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - June 9, 2018 Category: OBGYN Source Type: research

Combined laparoscopic and vaginal cervicovaginal reconstruction using acellular porcine small intestinal submucosa (SIS) graft in a patient with Mayer-Rokitansky-K üster-Hauser syndrome (U5aC4V4)
To introduce a creation that combines laparoscopic and Wharton-Sheares-George cervicovaginal reconstruction using SIS graft in a patient with Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome who had a rudimentary cavity (U5aC4V4). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - June 8, 2018 Category: OBGYN Authors: Xuyin Zhang, Yan Ding, Keqin Hua, Songping Liu, Nan Jia Tags: Video Article Source Type: research