Inverse Probability Weights for Quasi-Continuous Ordinal Exposures with a Binary Outcome: Method Comparison and Case Study
Am J Epidemiol. 2023 Apr 14:kwad085. doi: 10.1093/aje/kwad085. Online ahead of print.ABSTRACTInverse probability weighting (IPW), a well-established method to control for confounding in observational studies with binary exposures, has been extended to analyses with continuous exposures. Methods developed for continuous exposures may not apply when the exposure is quasi-continuous due to irregular exposure distributions that violate key assumptions. We used simulations and cluster-randomized clinical trial data to assess four approaches developed for continuous exposures - ordinary least squares (OLS), covariate balancing g...
Source: Am J Epidemiol - April 17, 2023 Category: Epidemiology Authors: Daniel E Sack Bryan E Shepherd Carolyn M Audet Caroline De Schacht Lauren R Samuels Source Type: research

Update on Wild Poliovirus Type 1 Outbreak - Southeastern Africa, 2021-2022
This report summarizes progress in the outbreak response since the initial report (5). During November 2021-December 2022, nine children and adolescents with paralytic polio caused by WPV1 were identified in southeastern Africa: one in Malawi and eight in Mozambique. Malawi, Mozambique, and three neighboring countries at high risk for WPV1 importation (Tanzania, Zambia, and Zimbabwe) responded by increasing surveillance and organizing up to six rounds of national and subnational polio supplementary immunization activities (SIAs).* Although no cases of paralytic WPV1 infection have been reported in Malawi since November 202...
Source: MMWR Morb Mortal Wkl... - April 13, 2023 Category: Epidemiology Authors: Elizabeth Davlantes Sharon A Greene Farrell A Tobolowsky Oladayo Biya Eric Wiesen Fikru Abebe Mesfin B Weldetsadik Victor A Eboh Mike N Chisema Balbina da Concei ção Mário Florian Tinuga Patricia Mupeta Bobo Colline Koline Chigodo Ghanashyam Sethy Jan- Source Type: research

Update on Wild Poliovirus Type 1 Outbreak - Southeastern Africa, 2021-2022
This report summarizes progress in the outbreak response since the initial report (5). During November 2021-December 2022, nine children and adolescents with paralytic polio caused by WPV1 were identified in southeastern Africa: one in Malawi and eight in Mozambique. Malawi, Mozambique, and three neighboring countries at high risk for WPV1 importation (Tanzania, Zambia, and Zimbabwe) responded by increasing surveillance and organizing up to six rounds of national and subnational polio supplementary immunization activities (SIAs).* Although no cases of paralytic WPV1 infection have been reported in Malawi since November 202...
Source: MMWR Morb Mortal Wkl... - April 13, 2023 Category: Epidemiology Authors: Elizabeth Davlantes Sharon A Greene Farrell A Tobolowsky Oladayo Biya Eric Wiesen Fikru Abebe Mesfin B Weldetsadik Victor A Eboh Mike N Chisema Balbina da Concei ção Mário Florian Tinuga Patricia Mupeta Bobo Colline Koline Chigodo Ghanashyam Sethy Jan- Source Type: research

Update on Wild Poliovirus Type 1 Outbreak - Southeastern Africa, 2021-2022
This report summarizes progress in the outbreak response since the initial report (5). During November 2021-December 2022, nine children and adolescents with paralytic polio caused by WPV1 were identified in southeastern Africa: one in Malawi and eight in Mozambique. Malawi, Mozambique, and three neighboring countries at high risk for WPV1 importation (Tanzania, Zambia, and Zimbabwe) responded by increasing surveillance and organizing up to six rounds of national and subnational polio supplementary immunization activities (SIAs).* Although no cases of paralytic WPV1 infection have been reported in Malawi since November 202...
Source: MMWR Morb Mortal Wkl... - April 13, 2023 Category: Epidemiology Authors: Elizabeth Davlantes Sharon A Greene Farrell A Tobolowsky Oladayo Biya Eric Wiesen Fikru Abebe Mesfin B Weldetsadik Victor A Eboh Mike N Chisema Balbina da Concei ção Mário Florian Tinuga Patricia Mupeta Bobo Colline Koline Chigodo Ghanashyam Sethy Jan- Source Type: research

Update on Wild Poliovirus Type 1 Outbreak - Southeastern Africa, 2021-2022
This report summarizes progress in the outbreak response since the initial report (5). During November 2021-December 2022, nine children and adolescents with paralytic polio caused by WPV1 were identified in southeastern Africa: one in Malawi and eight in Mozambique. Malawi, Mozambique, and three neighboring countries at high risk for WPV1 importation (Tanzania, Zambia, and Zimbabwe) responded by increasing surveillance and organizing up to six rounds of national and subnational polio supplementary immunization activities (SIAs).* Although no cases of paralytic WPV1 infection have been reported in Malawi since November 202...
Source: MMWR Morb Mortal Wkl... - April 13, 2023 Category: Epidemiology Authors: Elizabeth Davlantes Sharon A Greene Farrell A Tobolowsky Oladayo Biya Eric Wiesen Fikru Abebe Mesfin B Weldetsadik Victor A Eboh Mike N Chisema Balbina da Concei ção Mário Florian Tinuga Patricia Mupeta Bobo Colline Koline Chigodo Ghanashyam Sethy Jan- Source Type: research

Update on Wild Poliovirus Type 1 Outbreak - Southeastern Africa, 2021-2022
This report summarizes progress in the outbreak response since the initial report (5). During November 2021-December 2022, nine children and adolescents with paralytic polio caused by WPV1 were identified in southeastern Africa: one in Malawi and eight in Mozambique. Malawi, Mozambique, and three neighboring countries at high risk for WPV1 importation (Tanzania, Zambia, and Zimbabwe) responded by increasing surveillance and organizing up to six rounds of national and subnational polio supplementary immunization activities (SIAs).* Although no cases of paralytic WPV1 infection have been reported in Malawi since November 202...
Source: MMWR Morb Mortal Wkl... - April 13, 2023 Category: Epidemiology Authors: Elizabeth Davlantes Sharon A Greene Farrell A Tobolowsky Oladayo Biya Eric Wiesen Fikru Abebe Mesfin B Weldetsadik Victor A Eboh Mike N Chisema Balbina da Concei ção Mário Florian Tinuga Patricia Mupeta Bobo Colline Koline Chigodo Ghanashyam Sethy Jan- Source Type: research

Update on Wild Poliovirus Type 1 Outbreak - Southeastern Africa, 2021-2022
This report summarizes progress in the outbreak response since the initial report (5). During November 2021-December 2022, nine children and adolescents with paralytic polio caused by WPV1 were identified in southeastern Africa: one in Malawi and eight in Mozambique. Malawi, Mozambique, and three neighboring countries at high risk for WPV1 importation (Tanzania, Zambia, and Zimbabwe) responded by increasing surveillance and organizing up to six rounds of national and subnational polio supplementary immunization activities (SIAs).* Although no cases of paralytic WPV1 infection have been reported in Malawi since November 202...
Source: MMWR Morb Mortal Wkl... - April 13, 2023 Category: Epidemiology Authors: Elizabeth Davlantes Sharon A Greene Farrell A Tobolowsky Oladayo Biya Eric Wiesen Fikru Abebe Mesfin B Weldetsadik Victor A Eboh Mike N Chisema Balbina da Concei ção Mário Florian Tinuga Patricia Mupeta Bobo Colline Koline Chigodo Ghanashyam Sethy Jan- Source Type: research

Countrywide Mortality Surveillance for Action in Mozambique: Results from a National Sample-Based Vital Statistics System for Mortality and Cause of Death
Am J Trop Med Hyg. 2023 Apr 10:tpmd220367. doi: 10.4269/ajtmh.22-0367. Online ahead of print.ABSTRACTSub-Saharan Africa lacks timely, reliable, and accurate national data on mortality and causes of death (CODs). In 2018 Mozambique launched a sample registration system (Countrywide Mortality Surveillance for Action [COMSA]-Mozambique), which collects continuous birth, death, and COD data from 700 randomly selected clusters, a nationally representative population of 828,663 persons. Verbal and social autopsy interviews are conducted for COD determination. We analyzed data collected in 2019-2020 to report mortality rates and ...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Ivalda Macicame Almamy M Kante Emily Wilson Brian Gilbert Alain Koffi Sheila Nhachungue Celso Monjane Pedro Duce Antonio Adriano Sergio Chicumbe Ilesh Jani Henry D Kalter Abhirup Datta Scott Zeger Robert E Black Eduardo Samo Gudo Agbessi Amouzou COMSA-Moz Source Type: research

Correcting for Verbal Autopsy Misclassification Bias in Cause-Specific Mortality Estimates
Am J Trop Med Hyg. 2023 Apr 10:tpmd220318. doi: 10.4269/ajtmh.22-0318. Online ahead of print.ABSTRACTVerbal autopsies (VAs) are extensively used to determine cause of death (COD) in many low- and middle-income countries. However, COD determination from VA can be inaccurate. Computer coded verbal autopsy (CCVA) algorithms used for this task are imperfect and misclassify COD for a large proportion of deaths. If not accounted for, this misclassification leads to biased estimates of cause-specific mortality fractions (CSMFs), a critical piece in health-policy making. Recent work has demonstrated that the knowledge of the CCVA ...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Jacob Fiksel Brian Gilbert Emily Wilson Henry Kalter Almamy Kante Aveika Akum Dianna Blau Quique Bassat Ivalda Macicame Eduardo Samo Gudo Robert Black Scott Zeger Agbessi Amouzou Abhirup Datta Source Type: research

Verbal and Social Autopsy of Adult Deaths and Adult Care-Seeking Pattern in Mozambique, 2019-2020
Am J Trop Med Hyg. 2023 Apr 10:tpmd220548. doi: 10.4269/ajtmh.22-0548. Online ahead of print.ABSTRACTIn sub-Saharan Africa, recent data about causes of adult death and care-seeking during illnesses are limited. This analysis examines adult deaths using verbal and social autopsy data from a nationally and provincially representative sample registration system in Mozambique. Causes of death among those 18 years and older were assigned using the InSilicoVA algorithm, and underlying social causes were examined using the pathway to survival model. Care-seeking was analyzed in different groups to determine if care was sought fro...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Md Hafizur Rahman Ivalda Macicame Emily Wilson Sheila Nhachungue Agbessi Amouzou Source Type: research

Implementing the Countrywide Mortality Surveillance in Action in Mozambique: How Much Did It Cost?
In conclusion, establishing COMSA required large costs associated with infrastructure and technological investments. However, the system offers long-term benefits for real-time data generation and informing government decision-making for health.PMID:37037435 | DOI:10.4269/ajtmh.22-0438 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Safia S Jiwani Victor Am érico Mavie Emma Williams Almamy Malick Kante Agbessi Amouzou Source Type: research

Completeness and Factors Affecting Community Workers' Reporting of Births and Deaths in the Countrywide Mortality Surveillance for Action in Mozambique
Am J Trop Med Hyg. 2023 Apr 10:tpmd220537. doi: 10.4269/ajtmh.22-0537. Online ahead of print.ABSTRACTSince March 2018, the Countrywide Mortality Surveillance for Action project, implemented as a national sample registration system by the Mozambique Instituto Nacional de Saude and the Instituto Nacional de Estatistica in 700 geographic clusters randomly distributed across the 11 provinces, has trained and deployed community surveillance agents (CSAs) to report births and deaths in each cluster prospectively. An independent, retrospective data collection was conducted to assess the completeness of surveillance data. Record l...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Almamy M Kante Azarias Mulungo Mussagy Ibraimo Aveika Akum Nordino Titus Antonio Adriano Fred Van Dyk Ivalda Macicame Robert E Black Agbessi Amouzou COMSA-Mozambique Study Working Group Source Type: research

From External to Local: Opportunities and Lessons Learned from Transitioning COMSA-Mozambique
Am J Trop Med Hyg. 2023 Apr 10:tpmd220284. doi: 10.4269/ajtmh.22-0284. Online ahead of print.ABSTRACTDonor transitions, where externally funded programs transfer to country ownership and management, are increasingly common. The Countrywide Mortality Surveillance for Action - Mozambique (COMSA) project established a nationwide surveillance system capturing vital events at the community level with funding from the Bill and Melinda Gates Foundation. COMSA was implemented in partnership between Johns Hopkins University (a U.S.-based academic institution) and the Instituto Nacional de Saúde (National Institute for Health) and ...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Daniela C Rodr íguez Ivalda Macicame Antonio Adriano Sergio Chicumbe Pedro Duce Almamy Kante Victor A Mavie Etelvina Mbalane Sheila Nhachungue Nordino Titus Fred Van Dyk Agbessi Amouzou Source Type: research

A Qualitative Assessment of Community Acceptability and Its Determinants in the Implementation of Minimally Invasive Tissue Sampling in Children in Quelimane City, Mozambique
Am J Trop Med Hyg. 2023 Apr 10:tpmd220343. doi: 10.4269/ajtmh.22-0343. Online ahead of print.ABSTRACTThe Countrywide Mortality Surveillance for Action project aims to implement a child mortality surveillance program through strengthening vital registration event reporting (pregnancy, birth, and death) and investigating causes of death (CODs) based on verbal autopsies. In Quelimane (central Mozambique), Minimally Invasive Tissue Sampling (MITS) procedures were added to fine-tune the COD approaches. Before the implementation of MITS, an evaluation of the acceptability and ethical considerations of child mortality surveillanc...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Amilcar Maga ço Yara Alonso Maria Maixenchs Contardo Ambrosio Antonio Sitoe Pio Vitorino Dianna Blau Mischka Garel Robert Breiman Agbessi Amouzou Quique Bassat Inacio Mandomando John Blevins Khatia Munguambe Source Type: research

Multi-Cause Calibration of Verbal Autopsy-Based Cause-Specific Mortality Estimates of Children and Neonates in Mozambique
Am J Trop Med Hyg. 2023 Apr 10:tpmd220319. doi: 10.4269/ajtmh.22-0319. Online ahead of print.ABSTRACTThe Countrywide Mortality Surveillance for Action platform is collecting verbal autopsy (VA) records from a nationally representative sample in Mozambique. These records are used to estimate the national and subnational cause-specific mortality fractions (CSMFs) for children (1-59 months) and neonates (1-28 days). Cross-tabulation of VA-based cause-of-death (COD) determination against that from the minimally invasive tissue sampling (MITS) from the Child Health and Mortality Prevention project revealed important misclassifi...
Source: The American Journal of Tropical Medicine and Hygiene - April 10, 2023 Category: Tropical Medicine Authors: Brian Gilbert Jacob Fiksel Emily Wilson Henry Kalter Almamy Kante Aveika Akum Dianna Blau Quique Bassat Ivalda Macicame Eduardo Samo Gudo Robert Black Scott Zeger Agbessi Amouzou Abhirup Datta Source Type: research