Motor Neurone Disease Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Clinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALS
Condition: Motor Neuron Disease, Amyotrophic Lateral Sclerosis Intervention: Sponsors: Ambulanzpartner Soziotechnologie APST GmbH; Charite University, Berlin, Germany Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 10, 2023 Category: Research Source Type: clinical trials

Digital peer-to-peer support programme for informal caregivers of people living with motor neuron disease: study protocol for a multi-centre parallel group, single-blinded (outcome assessor) randomised controlled superiority trial
This study will examine the impact of a virtual peer support intervention on quality-of-life measures in informal caregivers of individuals with MND living in the community.Trial registrationClinicalTrials.gov: NCT04695210 (Source: Trials)
Source: Trials - February 20, 2023 Category: Research Source Type: clinical trials

Statistical analysis plan for the motor neuron disease systematic multi-arm adaptive randomised trial (MND-SMART)
DiscussionIn developing the statistical analysis plan, we had to carefully consider several issues such as multiple testing, estimand specification, interim analyses, and statistical analysis of the repeated measurements of ALS-FRS-R. This analysis plan attempts to balance multiple factors, including minimisation of bias, maximising power and precision, and deriving clinically interpretable summaries of treatment effects.Trial registrationEudraCT Number, 2019 –000099-41. Registered 2 October 2019,https://www.clinicaltrialsregister.eu/ctr-search/search?query=mnd-smartClinicalTrials.gov,NCT04302870. Registered 10 March 2020. (Source: Trials)
Source: Trials - January 16, 2023 Category: Research Source Type: clinical trials

Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
Conditions: ALS (Amyotrophic Lateral Sclerosis); Postpoliomyelitis Syndrome; Spinal Muscular Atrophy Intervention: Procedure: 128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-EMG) Sponsors: University of Dublin, Trinity College; Motor Neurone Disease Association, UK; Irish Research Council, IE; Research Motor Neuron, IE; Thierry Latran Foundation, FR; ALS Association, USA Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 23, 2022 Category: Research Source Type: clinical trials