Metabolism and metabolomics of opiates: a long way of forensic implications to unravel - Dinis-Oliveira RJ.
Opium poppy has important medical, socioeconomic, forensic and political implications. More than 80 benzylisoquinoline alkaloids have been described, many of them with relevant therapeutic properties such as morphine, codeine, papaverine and noscapine. Her... (Source: SafetyLit)
Source: SafetyLit - January 11, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The tale of a worrier – Louise ’ s story
I am a worrier (a phrase that you will see later became relevant !) – it’s in my nature, so you can imagine what something as significant as a sub-total abdominal hysterectomy did to the worrying part of my brain. Having said that, I was relatively calm (for me) in the weeks leading up to the surgery. I’m not sure why; maybe because I knew it was needed. I had a very large growing fibroid (equivalent of a 24 week pregnancy) and despite not having any of the usual heavy bleeding symptoms or pains, knew that it was far better out than in; or maybe because I had had a laparoscopic oopherectomy two years earlier for a ve...
Source: The Hysterectomy Association - January 7, 2019 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health hysterectomy stories subtotal hysterectomy Source Type: news

The tale of a worrier – Louise ’ s story
I am a worrier (a phrase that you will see later became relevant !) – it’s in my nature, so you can imagine what something as significant as a sub-total abdominal hysterectomy did to the worrying part of my brain. Having said that, I was relatively calm (for me) in the weeks leading up to the surgery. I’m not sure why; maybe because I knew it was needed. I had a very large growing fibroid (equivalent of a 24 week pregnancy) and despite not having any of the usual heavy bleeding symptoms or pains, knew that it was far better out than in; or maybe because I had had a laparoscopic oopherectomy two years earlier for a ve...
Source: The Hysterectomy Association - January 7, 2019 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health hysterectomy stories subtotal hysterectomy Source Type: news

Comparison between intravenous morphine versus fentanyl in acute pain relief in drug abusers with acute limb traumatic injury - Vahedi HSM, Hajebi H, Vahidi E, Nejati A, Saeedi M.
BACKGROUND: Rapid and effective pain relief in acute traumatic limb injuries (ATLI) is one of the most important roles of emergency physicians. In these situations, opioid addiction is an important concern because of the dependency on opioids. The study ai... (Source: SafetyLit)
Source: SafetyLit - January 3, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Morphine concentrations in human urine following poppy seed paste consumption - Özbunar E, Aydoğdu M, Döğer R, Bostancı Hİ, Koruyucu M, Akgür SA.
Papaver somniferum (opium poppy) is one of the world's oldest medicinal plants which are widely used for medicinal, nutritive and scientific purposes. Turkey is one of the major legal opium poppy producer countries in the world and the seed paste of the po... (Source: SafetyLit)
Source: SafetyLit - December 26, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

How tiny implant could help thousands blighted by crippling abdominal pain  
The matchbox box-sized device is being trialled on 30 NHS patients with a common condition of the pancreas and could slash the use of potent painkilling drugs like morphine. (Source: the Mail online | Health)
Source: the Mail online | Health - December 22, 2018 Category: Consumer Health News Source Type: news

The Weaponization of Narcan
Narcan, the trade name of the opiate antidote naloxone, has become a part of the modern lexicon. It can even be found in the Urban Dictionary. Although initially a noun, it is now a widely used verb as in, “I Narcanned that patient,” or, “I Narcanned your Honor Student.” Narcan is so effective that we have even dreamed up imaginary clinical situations to administer it. YouTube is full of videos of police officers giving themselves or colleagues Narcan for suspected “fentanyl exposure.” A popular video shows a police officer giving Narcan to another officer after exposure to what was later identified as methamph...
Source: JEMS Special Topics - December 21, 2018 Category: Emergency Medicine Authors: Bryan Bledsoe, DO, FACEP, FAEMS Tags: Airway & Respiratory Exclusive Articles Columns Source Type: news

Vaccine could help address the opioid epidemic
(American College of Neuropsychopharmacology) Synthetic psychoactive drugs have become a serious public health threat in recent years. This is particularly true of the fentanyls, a large family of synthetic opioids, which can be up to 10,000 times more potent than morphine. Synthetic opioids are highly addictive and, because of their potency, often prove fatal: among the roughly 72,000 drug overdose deaths in the US in 2017, some 30,000 were related to synthetic opioids. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - December 13, 2018 Category: International Medicine & Public Health Source Type: news

Fentanyl Surpasses Heroin As Drug Most Often Involved In Deadly Overdoses
When fentanyl, a synthetic opioid 50 to 100 times more powerful than morphine, infiltrated the drug supply in the U.S. it had an immediate, dramatic effect on the overdose rate. (Image credit: Towfiqu Photography/Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - December 13, 2018 Category: Consumer Health News Authors: Laurel Wamsley Source Type: news

Overdose Deaths Involving Fentanyl Doubled Every Year From 2013 to 2016
Drug overdose deaths involving the potent synthetic opioid fentanyl are on the rise, and the number of fentanyl-related deaths roughly doubled each year from 2013 through 2016, according to new federal data. Researchers from the Centers for Disease Control and Prevention’s (CDC) National Center for Health Statistics (NCHS) reviewed death certificates filed from 2011 to 2016 to find out which drugs were mentioned most frequently each year. During this time period, drug overdose deaths increased from 41,340 in 2011 to 63,632 in 2016. Just as striking as the overall uptick, however, was the sharp increase in deaths invo...
Source: TIME: Health - December 12, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime public health Source Type: news

SAPB for Minimal Invasive Heart Surgery SAPB for Minimal Invasive Heart Surgery
Can serratus anterior plane block reduce morphine consumption and improve management of post-operative pain when compared with continuous wound infiltration following minimal invasive heart surgery?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

China Has Promised to Crack Down on Fentanyl. Here ’s What That Could Mean for Overdose Deaths in the U.S.
As part of a wide-ranging deal between President Donald Trump and Chinese leader Xi Jinping, China has reportedly pledged to designate the potent synthetic opioid fentanyl and similar drugs as controlled substances, subjecting those who sell them to harsher punishments and potentially slowing their flow into the U.S. Last month, a Congressional commission said China — which it previously called the “largest source of illicit fentanyl and fentanyl-like substances in the United States” — was not doing enough to stop the drug and its related analogs from reaching U.S. borders. The Trump Administration ...
Source: TIME: Health - December 3, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized China healthytime onetime public health Source Type: news

Fentanyl in cocaine: The deadly truth of new drugs cocktail
A surge in cocaine deaths is being blamed on fentanyl, a synthetic opioid far stronger than morphine. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 26, 2018 Category: Consumer Health News Source Type: news

Study Shows Cancer Patients Can Benefit from Opioid Switching
Switching from one prescription opioid to another often solves the problem of debilitating side effects or inadequate pain relief, according to a recent study involving a wide range of cancer patients. Opioids are not all the same. And neither are those they are helping. Despite the increasing government restrictions and the frenzy over potential abuse, opioids can be a lifesaver for a mesothelioma patient finding the right fit. “I’ve been through both sides of that switching issue,” said Tim Crisler, a 16-year pleural mesothelioma survivor told The Mesothelioma Center at Asbestos.com. “It worked great for me once,...
Source: Asbestos and Mesothelioma News - November 26, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news