Doctors are not always right – Caroline ’ s story
My experience began with a blood test as I was post menopause and started bleeding. The blood test had a high ca125 reading, never heard of this before but could be an indicator of ovarian cancer I was told. This was Xmas eve. Went for different scans, tests and 3 months of waiting and was told I had a 16cm mass on ovary. I couldn’t tell if cancer or not until come out. The shock took my breath away. No other symptoms,I always thought I was a strong woman but this floored me, even had to take time off work as it filled my head every waking moment. This seen me booked in for a total hysterectomy, vertical incision in orde...
Source: The Hysterectomy Association - April 27, 2019 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health cancer hysterectomy stories Source Type: news

Tanzania: Morphine Is Coming Around Again to Tanzania
[East African] Tanzania has said a new consignment of morphine will be available this month. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 22, 2019 Category: African Health Source Type: news

Peripheral Nerve Block May Cut Opioid Use After Amputation
WEDNESDAY, April 10, 2019 -- Peripheral nerve blockade with regular local anesthetic and liposomal bupivacaine is associated with lower oral morphine equivalent (OME) use at 72 hours after major lower extremity amputation (MLEA), according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 10, 2019 Category: Pharmaceuticals Source Type: news

TRPV1 promotes opioid analgesia during inflammation
Pain and inflammation are inherently linked responses to injury, infection, or chronic diseases. Given that acute inflammation in humans or mice enhances the analgesic properties of opioids, there is much interest in determining the inflammatory transducers that prime opioid receptor signaling in primary afferent nociceptors. Here, we found that activation of the transient receptor potential vanilloid type 1 (TRPV1) channel stimulated a mitogen-activated protein kinase (MAPK) signaling pathway that was accompanied by the shuttling of the scaffold protein β-arrestin2 to the nucleus. The nuclear translocation of β-...
Source: Signal Transduction Knowledge Environment - April 1, 2019 Category: Science Authors: Basso, L., Aboushousha, R., Fan, C. Y., Iftinca, M., Melo, H., Flynn, R., Agosti, F., Hollenberg, M. D., Thompson, R., Bourinet, E., Trang, T., Altier, C. Tags: STKE Research Articles Source Type: news

Poppy Seed Overdose Prompts Lawsuit
The parents of a Fayetteville man who died of a morphine overdose after drinking tea he made from poppy seeds he ordered from Amazon are suing the online retailer and Sincerely Nuts Inc. of New York, which marketed and sold the 5-pound bag of poppy seeds. (Source: Arkansas Business - Health Care)
Source: Arkansas Business - Health Care - April 1, 2019 Category: American Health Source Type: news

Tanzania: Tanzania Faces Shortage of Pain-Relieving Morphine
[East African] Tanzania is running out of morphine -- a key reliever of severe pain for patients with terminal illnesses. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 27, 2019 Category: African Health Source Type: news

My sub-total hysterectomy – Louise ’ s story
I am a worrier (a phrase that you will see later became relevant !) – it’s in my nature, so you can imagine what something as significant as a sub-total abdominal hysterectomy did to the worrying part of my brain. Having said that, I was relatively calm in the weeks leading up to the surgery. I’m not sure why; maybe because I knew it was needed, I had a very large growing fibroid (equivalent of a 24 week pregnancy) and despite not having any of the usual heavy bleeding symptoms or pains, knew that it was far better out than in; or maybe because I had had a laparoscopic oopherectomy two years earlier for a very large ...
Source: The Hysterectomy Association - March 22, 2019 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health abdominal hysterectomy fibroids hysterectomy stories subtotal hysterectomy Source Type: news

My sub-total hysterectomy – Louise ’ s story
I am a worrier (a phrase that you will see later became relevant !) – it’s in my nature, so you can imagine what something as significant as a sub-total abdominal hysterectomy did to the worrying part of my brain. Having said that, I was relatively calm in the weeks leading up to the surgery. I’m not sure why; maybe because I knew it was needed, I had a very large growing fibroid (equivalent of a 24 week pregnancy) and despite not having any of the usual heavy bleeding symptoms or pains, knew that it was far better out than in; or maybe because I had had a laparoscopic oopherectomy two years earlier for a very large ...
Source: The Hysterectomy Association - March 22, 2019 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health abdominal hysterectomy fibroids hysterectomy stories subtotal hysterectomy Source Type: news

Statex (Morphine Sulfate Drops, Suppositories, Syrup, Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 22, 2019 Category: Drugs & Pharmacology Source Type: news

Standardized Morphine Infusions for Use in Children Standardized Morphine Infusions for Use in Children
This study investigated the feasibility and safety of quality assured, standardized concentrations of pediatric nurse/patient-controlled morphine infusions, supplied as pre-filled syringes.BMC Anesthesiology (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - March 19, 2019 Category: Intensive Care Tags: Anesthesiology Journal Article Source Type: news

The Guardian view on opioids in the the UK: poverty and pain | Editorial
These painkillers don ’t work against chronic pain. The UK must find alternatives to help sufferers in deprived areasPeople in Blackpool are twice as likely as the inhabitants of Wokingham to die before they are 70. Arecent paper which measured the distribution of opioids not by the number of prescriptions, but in equivalent units of morphine, found that NHS prescriptions of opioid painkillers have been generally rising in England and Wales, but have risen most in the north of England and more in poorer areas. Blackpool, again,tops the list. In part this is because poverty is correlated with chronic physical pain: both m...
Source: Guardian Unlimited Science - February 28, 2019 Category: Science Authors: Editorial Tags: Opioids Poverty Social exclusion Society Drugs Science Opioids crisis US news NHS Health GPs Doctors Conservatives Politics Austerity Economics Business Source Type: news

Opiate prescribing practices after common isolated lower extremity injuries - Rodriguez-Buitrago A, Attum B, Enata N, Evans A, Okwumabua E, Gajari V, Obremskey WT, Jahangir A.
OBJECTIVE: This retrospective study aimed at identifying opiate prescribing practices, the number of morphine milligram equivalents (MMEs) prescribed by orthopaedic and nonorthopaedic providers in patients with operatively treated isolated lower extremity ... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news