Live vaccinations in dermatology for immunosuppressed patients: a narrative review
Arch Dermatol Res. 2024 Mar 2;316(3):96. doi: 10.1007/s00403-024-02827-2.ABSTRACTGiven the higher susceptibility to infectious disease in patients receiving immunosuppressive therapies for inflammatory dermatologic conditions, immunization is important in this population. While live vaccines protect against life-threatening diseases, they can be harmful in immunosuppressed patients given the risk of replication of the attenuated pathogen and adverse reactions. The utilization of live vaccines in immunosuppressed patients depends on multiple factors such as the vaccine and therapy regimen. To provide an overview of evidence...
Source: Herpes - March 2, 2024 Category: Infectious Diseases Authors: Divya M Shan Rithi J Chandy Andrew Fultz John W Sanders Steven R Feldman Source Type: research

Live vaccinations in dermatology for immunosuppressed patients: a narrative review
Arch Dermatol Res. 2024 Mar 2;316(3):96. doi: 10.1007/s00403-024-02827-2.ABSTRACTGiven the higher susceptibility to infectious disease in patients receiving immunosuppressive therapies for inflammatory dermatologic conditions, immunization is important in this population. While live vaccines protect against life-threatening diseases, they can be harmful in immunosuppressed patients given the risk of replication of the attenuated pathogen and adverse reactions. The utilization of live vaccines in immunosuppressed patients depends on multiple factors such as the vaccine and therapy regimen. To provide an overview of evidence...
Source: Herpes - March 2, 2024 Category: Infectious Diseases Authors: Divya M Shan Rithi J Chandy Andrew Fultz John W Sanders Steven R Feldman Source Type: research

Live vaccinations in dermatology for immunosuppressed patients: a narrative review
AbstractGiven the higher susceptibility to infectious disease in patients receiving immunosuppressive therapies for inflammatory dermatologic conditions, immunization is important in this population. While live vaccines protect against life-threatening diseases, they can be harmful in immunosuppressed patients given the risk of replication of the attenuated pathogen and adverse reactions. The utilization of live vaccines in immunosuppressed patients depends on multiple factors such as the vaccine and therapy regimen. To provide an overview of evidence-based recommendations for the use of live vaccines in patients receiving...
Source: Archives of Dermatological Research - March 2, 2024 Category: Dermatology Source Type: research

Effectiveness of the combined MMRV Priorix-Tetra ™ vaccine against varicella in a large Italian region: A case-control study
In this study, we aimed to estimate the effectiveness of the combined measles-mumps-rubella-varicella Priorix-Tetra™ vaccine against varicella in real-world conditions. We conducted a post-marketing retrospective case-control study in the Apulia region of Italy in children aged 1-9 years born between January 1, 2008 and December 31, 2016. We assessed the effectiveness against varicella of all grades of severity (including hospitalisation) and against hospitalisation for varicella of a single and two doses of Priorix-Tetra™. Moreover, we also assessed effectiveness of monovalent varicella (monovalent-V) vaccine and any ...
Source: Vaccine - February 10, 2024 Category: Allergy & Immunology Authors: Francesca Fortunato Angelo Musco Giuseppina Iannelli Martina Meola Pier Luigi Lopalco Domenico Martinelli Source Type: research

Varicella vaccine meningoencephalitis in a child receiving autologous bone marrow transplantation
CONCLUSIONS: Our experience highlights the importance of conducting a thorough medical history regarding vaccination and serological status of newly immunocompromised patients. Intensive chemotherapy succeeding live vaccine administration <4 weeks could have influenced early and severe viral reactivation. Early initiation of prophylactic antiviral treatment is questioned in such circumstances.PMID:37395442 | DOI:10.1111/petr.14562 (Source: Herpes)
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Raad Coralie Chebel Ziad Renaud Christian Teira Pierre Buteau Chantal Tapi éro Bruce Ovetchkine Philippe Source Type: research

Varicella vaccine meningoencephalitis in a child receiving autologous bone marrow transplantation
CONCLUSIONS: Our experience highlights the importance of conducting a thorough medical history regarding vaccination and serological status of newly immunocompromised patients. Intensive chemotherapy succeeding live vaccine administration <4 weeks could have influenced early and severe viral reactivation. Early initiation of prophylactic antiviral treatment is questioned in such circumstances.PMID:37395442 | DOI:10.1111/petr.14562 (Source: Herpes)
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Raad Coralie Chebel Ziad Renaud Christian Teira Pierre Buteau Chantal Tapi éro Bruce Ovetchkine Philippe Source Type: research

Universal varicella vaccination in Denmark: Modeling public health impact, age-shift, and cost-effectiveness
In conclusion, all modeled two-dose UVV strategies were projected to substantially reduce the clinical and economic burden of varicella disease in Denmark compared to the current no vaccination strategy, with declines in both varicella and zoster incidence for all age groups over a 50-year time horizon.PMID:37018165 | DOI:10.1371/journal.pgph.0001743 (Source: Herpes)
Source: Herpes - April 5, 2023 Category: Infectious Diseases Authors: Colleen Burgess Salome Samant Thomas leFevre Carsten Schade Larsen Manjiri Pawaskar Source Type: research

Factors associated with incomplete vaccination and negative antibody test results for measles, mumps, and hepatitis A among children followed in the MINA-BRAZIL cohort
In this study, we aimed to investigate the frequency of vaccine adherence, factors associated with incomplete vaccination for measles, mumps, rubella (MMR) and hepatitis A, and factors associated with the seronegative test results for measles, mumps and hepatitis A at 2 years of age. This was a population-based cohort that addressed health conditions and mother/infant nutrition in Cruzeiro do Sul city, Brazil. Vaccination data were obtained from official certificates of immunization. The children underwent blood collection at the two-year-old follow-up visit; the samples were analyzed using commercially available kits to m...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - March 15, 2023 Category: Tropical Medicine Authors: Midi ã Silva Ferreira Marly Augusto Cardoso Lalucha Mazzucchetti Ester Cerdeira Sabino Vivian Iida Avelino-Silva Source Type: research

Factors associated with incomplete vaccination and negative antibody test results for measles, mumps, and hepatitis A among children followed in the MINA-BRAZIL cohort
In this study, we aimed to investigate the frequency of vaccine adherence, factors associated with incomplete vaccination for measles, mumps, rubella (MMR) and hepatitis A, and factors associated with the seronegative test results for measles, mumps and hepatitis A at 2 years of age. This was a population-based cohort that addressed health conditions and mother/infant nutrition in Cruzeiro do Sul city, Brazil. Vaccination data were obtained from official certificates of immunization. The children underwent blood collection at the two-year-old follow-up visit; the samples were analyzed using commercially available kits to m...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - March 15, 2023 Category: Tropical Medicine Authors: Midi ã Silva Ferreira Marly Augusto Cardoso Lalucha Mazzucchetti Ester Cerdeira Sabino Vivian Iida Avelino-Silva Source Type: research

Factors associated with incomplete vaccination and negative antibody test results for measles, mumps, and hepatitis A among children followed in the MINA-BRAZIL cohort
In this study, we aimed to investigate the frequency of vaccine adherence, factors associated with incomplete vaccination for measles, mumps, rubella (MMR) and hepatitis A, and factors associated with the seronegative test results for measles, mumps and hepatitis A at 2 years of age. This was a population-based cohort that addressed health conditions and mother/infant nutrition in Cruzeiro do Sul city, Brazil. Vaccination data were obtained from official certificates of immunization. The children underwent blood collection at the two-year-old follow-up visit; the samples were analyzed using commercially available kits to m...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - March 15, 2023 Category: Tropical Medicine Authors: Midi ã Silva Ferreira Marly Augusto Cardoso Lalucha Mazzucchetti Ester Cerdeira Sabino Vivian Iida Avelino-Silva Source Type: research

Factors associated with incomplete vaccination and negative antibody test results for measles, mumps, and hepatitis A among children followed in the MINA-BRAZIL cohort
In this study, we aimed to investigate the frequency of vaccine adherence, factors associated with incomplete vaccination for measles, mumps, rubella (MMR) and hepatitis A, and factors associated with the seronegative test results for measles, mumps and hepatitis A at 2 years of age. This was a population-based cohort that addressed health conditions and mother/infant nutrition in Cruzeiro do Sul city, Brazil. Vaccination data were obtained from official certificates of immunization. The children underwent blood collection at the two-year-old follow-up visit; the samples were analyzed using commercially available kits to m...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - March 15, 2023 Category: Tropical Medicine Authors: Midi ã Silva Ferreira Marly Augusto Cardoso Lalucha Mazzucchetti Ester Cerdeira Sabino Vivian Iida Avelino-Silva Source Type: research

Factors associated with incomplete vaccination and negative antibody test results for measles, mumps, and hepatitis A among children followed in the MINA-BRAZIL cohort
In this study, we aimed to investigate the frequency of vaccine adherence, factors associated with incomplete vaccination for measles, mumps, rubella (MMR) and hepatitis A, and factors associated with the seronegative test results for measles, mumps and hepatitis A at 2 years of age. This was a population-based cohort that addressed health conditions and mother/infant nutrition in Cruzeiro do Sul city, Brazil. Vaccination data were obtained from official certificates of immunization. The children underwent blood collection at the two-year-old follow-up visit; the samples were analyzed using commercially available kits to m...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - March 15, 2023 Category: Tropical Medicine Authors: Midi ã Silva Ferreira Marly Augusto Cardoso Lalucha Mazzucchetti Ester Cerdeira Sabino Vivian Iida Avelino-Silva Source Type: research

Accounting for Adverse Events Following Immunization in Economic Evaluation: Systematic Review of Economic Evaluations of Pediatric Vaccines Against Pneumococcus, Rotavirus, Human Papillomavirus, Meningococcus and Measles-Mumps-Rubella-Varicella
DiscussionAlthough (mild) AEFI were demonstrated for all five studied vaccines, only a quarter of reviewed studies accounted for these, mostly in an incomplete and inaccurate manner. We provide guidance on which methods to use to better quantify the impact of AEFI on both costs and health outcomes. Policymakers should be aware that the impact of AEFI on cost-effectiveness is likely to be underestimated in the majority of economic evaluations. (Source: PharmacoEconomics)
Source: PharmacoEconomics - February 21, 2023 Category: Health Management Source Type: research