Diagnostic Yield of head Computed Tomography in Patients with Syncope: Sex Differences
CONCLUSIONS: Age had a more significant impact on diagnostic yield of syncope than head CT. The use of a head CT scan as a routine diagnosis tool in patients with syncope is unjustifiable unless there is an indication based on medical history or physical examination.PMID:38616670 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Raymond Farah Dvir Novak Rola Khamisy-Farah Source Type: research

Electrocautery-induced Inappropriate Implantable Cardiac Defibrillator Shock
Isr Med Assoc J. 2024 Apr;26(4):245-246.NO ABSTRACTPMID:38616671 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Dante Antonelli Vladimir Poletaev Vidal Essebag Alexander Feldman Source Type: research

Klatskin Signet Ring Cell Neuroendocrine Tumor of the Biliary Tree
Isr Med Assoc J. 2024 Apr;26(4):247-250.NO ABSTRACTPMID:38616672 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Eden Gerszman Esther Kazlow Victoria Vlasov Dvir Froylich Jacob Dickstein Riad Haddad Ahmad Mahamid Source Type: research

Cardiac Tamponade: A Rare and Insidious Surgical Complication of Hiatal Hernia Repair
Isr Med Assoc J. 2024 Apr;26(4):251-253.NO ABSTRACTPMID:38616673 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Roy Apel Slava Bard Ari Naimark Nikolai Menasherov Nir Wasserberg Ory Wiesel Source Type: research

Es geht wohl anders [Things Turn Out Differently]
Isr Med Assoc J. 2024 Apr;26(4):254-258.NO ABSTRACTPMID:38616674 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Avi Ohry Esteban Gonz ález-López Source Type: research

The Healthcare System in Theresienstadt: Heroism and Challenges
Isr Med Assoc J. 2024 Apr;26(4):259-265.NO ABSTRACTPMID:38616675 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Philip J Hashkes Source Type: research

A Personal View: The Post-Captivity Condition
Isr Med Assoc J. 2024 Apr;26(4):266-268.NO ABSTRACTPMID:38616676 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Avi Ohry Source Type: research

Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient
CONCLUSION: A gradient in vaccine effectiveness exists and is linked to the symptoms and severity of infection, providing higher protection against more symptomatic and severe cases. This gradient intensifies over time as vaccine immunity wanes after the last vaccine dose. These patterns appear consistent irrespective of the vaccine type or whether the vaccination involves the primary series or a booster.PMID:38616439 | DOI:10.1016/j.vaccine.2024.04.026 (Source: Vaccine)
Source: Vaccine - April 15, 2024 Category: Allergy & Immunology Authors: Layan Sukik Hiam Chemaitelly Houssein H Ayoub Peter Coyle Patrick Tang Hadi M Yassine Asmaa A Al Thani Mohammad R Hasan Zaina Al-Kanaani Einas Al-Kuwari Andrew Jeremijenko Anvar Hassan Kaleeckal Ali Nizar Latif Riyazuddin Mohammad Shaik Hanan F Abdul-Rahi Source Type: research

The impact of phospholipids with high transition temperature to enhance Redox-Sensitive liposomal doxorubicin efficacy in colon carcinoma model
In this study, we have developed a redox-sensitive (RS) liposomal doxorubicin formulation by incorporating 10,10'-diselanediylbis decanoic acid (DDA) organoselenium compound as the RS moiety. Hence, several RS liposomal formulations were prepared by using DOPE, HSPC, DDA, mPEG2000-DSPE, and cholesterol. In situ drug loading using a pH gradient and citrate complex yielded high drug to lipid ratio and encapsulation efficiency (100%) for RS liposomes. Liposomal formulations were characterized in terms of size, surface charge and morphology, drug loading, release properties, cell uptake and cytotoxicity, as well as therapeutic...
Source: Chemistry and Physics of Lipids - April 15, 2024 Category: Lipidology Authors: Elaheh Mirhadi Anis Askarizadeh Leila Farhoudi Mohammad Mashreghi Saeed Behboodifar Seyedeh Hoda Alavizadeh Leila Arabi Mahmoud Reza Jaafari Source Type: research

Recommended approaches for screening and early detection of lung cancer in the Middle East and Africa (MEA) region: a consensus statement
CONCLUSIONS: There is a great need for large-scale screening programs, preferably integrated with tobacco-control programs and awareness programs for physicians and patients, which may facilitate higher adherence to lung cancer screening and improve survival outcomes.PMID:38617789 | PMC:PMC11009596 | DOI:10.21037/jtd-23-1568 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ahmed Allehebi Ameen Al-Omair Bassam Mahboub Coenraad F Koegelenberg Mohsen Mokhtar Ashraf Mokhtar Madkour Khaled Al-Asad Ugur Selek Humaid O Al-Shamsi Source Type: research

Prevalence and genetic characteristics of  Staphylococcus aureus isolates from cell phones of medical students from Iran
Acta Microbiol Immunol Hung. 2024 Apr 15. doi: 10.1556/030.2024.02193. Online ahead of print.ABSTRACTAlthough mobile phones as a rapid communication vehicle can lead to improved quality of healthcare, they can also facilitate the transmission of pathogens to patients. This current research focuses on genetic diversity, and genes involved in resistance and biofilm production of Staphylococcus aureus isolates from mobile phones of medical students. Antibiotic resistance profiling and polymerase chain reaction (PCR) amplification of antibiotic resistance and biofilm-related genes were investigated and statistically analyzed. ...
Source: Acta Microbiologica et Immunologica Hungarica - April 15, 2024 Category: Microbiology Authors: Fatemeh Behrouzmanesh Sahar Ahmad Samali Rozhin Nasehi Ali Shivaee Mehdi Goudarzi Source Type: research

Predictors of Impairment and Self-Concept in Children and Adolescents with Persistent Tic Disorder
This study examined predictors of, and associations between, self-concept, demographic variables, and clinical measures in fifty-eight children and adolescents with Persistent Tic Disorder (PTD; 44 males, Mage = 11.9 years, SD = 2.74). Participants completed measures that assessed self-concept, tic severity, tic-related impairment, and comorbid psychological symptoms. Results showed that generalized anxiety disorder, major depressive disorder, persistent depressive disorder, total tic severity, number and complexity of tics, and total and social tic-related impairment were associated with self-concept. Tic-related social i...
Source: Child Psychiatry and Human Development - April 15, 2024 Category: Child Development Authors: Kirsten R Bootes Michael B Himle Jordan T Stiede Brianna C M Wellen Suzanne Mouton-Odum Douglas W Woods Source Type: research

Evaluation of the Patients with the Diagnosis of Pontocerebellar Hypoplasia: A Multicenter National Study
Cerebellum. 2024 Apr 15. doi: 10.1007/s12311-024-01690-1. Online ahead of print.ABSTRACTPontocerebellar hypoplasia (PCH) is a heterogeneous group of neurodegenerative disorders characterized by hypoplasia and degeneration of the cerebellum and pons. We aimed to identify the clinical, laboratory, and imaging findings of the patients with diagnosed PCH with confirmed genetic analysis. We collected available clinical data, laboratory, and imaging findings in our retrospective multicenter national study of 64 patients with PCH in Turkey. The genetic analysis included the whole-exome sequencing (WES), targeted next-generation s...
Source: Cerebellum - April 15, 2024 Category: Neuroscience Authors: Dilek Cavusoglu Gulten Ozturk Dilsad Turkdogan Semra Hiz Kurul Uluc Yis Mustafa Komur Faruk Incecik Bulent Kara Turkan Sahin Olcay Unver Cengiz Dilber Gulen Gul Mert Cagatay Gunay Gamze Sarikaya Uzan Ozlem Ersoy Yavuz Oktay Serdar Mermer Gokcen Oz Tuncer Source Type: research

Exploring the County Level Mortality Pattern Variations in Rural Areas of Iran (2006- 2016)
CONCLUSION: The findings indicate significant spatial and temporal variations in rural mortality rates in Iran. Policymakers can use this information to plan and enhance healthcare infrastructure in specific counties. The findings serve for evaluating the effectiveness of health policies, enabling policymakers to make informed decisions, allocate resources efficiently and design targeted interventions for improved public health outcomes.PMID:38618838 | DOI:10.34172/ijhpm.2024.8032 (Source: Rural Remote Health)
Source: Rural Remote Health - April 15, 2024 Category: Rural Health Authors: Mehrangiz Rezaee Nader Tavakoli Siamak Tahmasbi Source Type: research

Structure characterization and protective effect against UVB irradiation of polysaccharides isolated from the plateau plant Gentiana dahurica Fisch
Int J Biol Macromol. 2024 Apr 13:131551. doi: 10.1016/j.ijbiomac.2024.131551. Online ahead of print.ABSTRACTGentiana dahurica Fisch. (G. dahurica) is one of the legitimate sources of Qinjiao in Traditional Chinese Medicine (TCM) and grows on high-altitude plateaus. Plants develop unique biochemical accumulations to resist plateau conditions, especially the strong UV irradiation. Thus, this study aimed to investigate the polysaccharide of G. dahurica (GDP), its structure and its activity against UVB irradiation. Four GDPs were isolated and two of them were subjected to structural elucidation. The results suggested that GDP-...
Source: International Journal of Biological Macromolecules - April 15, 2024 Category: Biochemistry Authors: Wen Ji Cuiyin Qian Xiaopeng Su Xiang Li Zhenqing Zhang Yonggui Ma Mingjin Zhang Duxin Li Source Type: research