What factors are effective on the CPR duration of patients under extracorporeal cardiopulmonary resuscitation: a single-center retrospective study
ConclusionThese findings suggest that age, SOFA score, comorbidities, OHCA, collapse-to-CPR time, and initial shockable rhythm are important factors influencing the duration of CPR in patients undergoing ECPR. Understanding these factors can help healthcare providers better predict and manage CPR duration, potentially improving patient outcomes. Further research is warranted to validate these findings and explore additional factors that may impact CPR duration in this population. (Source: International Journal of Emergency Medicine)
Source: International Journal of Emergency Medicine - April 17, 2024 Category: Emergency Medicine Source Type: research
Viruses, Vol. 16, Pages 621: Chimeric Porcine Parvovirus VP2 Virus-like Particles with Epitopes of South African Serotype 2 Foot-and-Mouth Disease Virus Elicits Specific Humoral and Cellular Responses in Mice
In this study, chimeric porcine parvovirus VP2 VLPs (chimeric PPV-SAT2-VLPs) expressing the T-and/or B-cell epitopes of the structural protein VP1 of FMDV SAT2 were produced using the recombinant pFastBac™ Dual vector of baculoviruses in Sf9 and HF cells We used the Bac-to-Bac system to construct the recombinant baculoviruses. The VP2-VLP--SAT2 chimeras displayed chimeric T-cell epitope (amino acids 21–40 of VP1) and/or the B-cell epitope (amino acids 135–174) of SAT FMDV VP1 by substitution of the corresponding regions at the N terminus (amino acids 2–23) and/or loop...
Source: Viruses - April 17, 2024 Category: Virology Authors: Qian Li Xusheng Ma Yaner Shen Junfei Dai Xiaofeng Nian Xiaofen Shang Jiao Chen Ashenafi Kiros Wubshet Jie Zhang Haixue Zheng Tags: Article Source Type: research
Mechanistic drivers of chromatin organization into compartments
Curr Opin Genet Dev. 2024 Apr 15;86:102193. doi: 10.1016/j.gde.2024.102193. Online ahead of print.ABSTRACTThe human genome is not just a simple string of DNA, it is a complex and dynamic entity intricately folded within the cell's nucleus. This three-dimensional organization of chromatin, the combination of DNA and proteins in the nucleus, is crucial for many biological processes and has been prominently studied for its intricate relationship to gene expression. Indeed, the transcriptional machinery does not operate in isolation but interacts intimately with the folded chromatin structure. Techniques for chromatin conforma...
Source: Current Opinion in Genetics and Development - April 16, 2024 Category: Genetics & Stem Cells Authors: Hannah L Harris M Jordan Rowley Source Type: research
How Nurse Faculty in Saudi Arabia View Their Competencies in All Aspects of the Faculty Role: A Descriptive Study
This study used a quantitative descriptive survey with a sample of 92 participants to assess perceived nurse faculty competency in their role at Saudi Arabian universities. Participants' perceptions overall were highly positive in the areas of teaching, scholarship, and service competencies. Participants reported less competence in the areas of scholarship and service when they started in their role. Orientation and a mentor relationship with senior faculty were reported to aid in their transition to the faculty role. The findings of the study identify strategies to support the new nurse educator.PMID:38625709 | DOI:10.109...
Source: Nursing Education Perspectives - April 16, 2024 Category: Nursing Authors: Fadiyah Jadid Alanazi Rose A Rossi Source Type: research
Comparative Analysis of Transoral Endoscopic Parathyroidectomy Vestibular Approach and Focused Open Surgery for Primary Hyperparathyroidism Treatment: A Single Center Experience
CONCLUSIONS TOEPVA is a safe method in patients who underwent parthyroid surgery to avoid cervical scarring.PMID:38622842 | PMC:PMC11032083 | DOI:10.12659/MSM.944128 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 16, 2024 Category: Research Authors: Mehmet Zafer Sabuncuoglu Isa Sozen İsmail Zihni Girayhan Celik Nesime Inci Ery ılmaz Fatma Nur Dal Demet Gunduz Ozer Makay Source Type: research
The Quality of Life of Urban Omani People During the COVID-19 Pandemic in A'Seeb Wilayat: A Cross-sectional Study
CONCLUSIONS: Physical and mental impacts are very common during the COVID-19 pandemic. Several risk factors were identified. Public health programs need to be implemented to mitigate the negative impact of COVID-19 on quality of life.PMID:38623538 | PMC:PMC11016751 | DOI:10.5001/omj.2024.51 (Source: Oman Medical Journal)
Source: Oman Medical Journal - April 16, 2024 Category: Middle East Health Authors: Mohammed Al Hinai Zalikha Issa Al Belushi Asma Said Al Shidhani Maisa Hamed Al Kiyumi Source Type: research
Unlocking the power of global collaboration: building a stronger evidence ecosystem together
Cochrane Database Syst Rev. 2024 Apr 16;4(4):ED000166. doi: 10.1002/14651858.ED000166.NO ABSTRACTPMID:38623686 | PMC:PMC11019402 | DOI:10.1002/14651858.ED000166 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 16, 2024 Category: General Medicine Authors: Zoe Jordan Vivian Welch Karla Soares-Weiser Source Type: research
Establishment of National Diagnostic Reference Levels for Administered Activity in Diagnostic Nuclear Medicine in Thailand
Conclusion: This study presents NDRL results for adults in Thailand as a way to optimize radiation protection in nuclear medicine imaging. Moreover, the reported injected activity levels were comparable to those of other countries.PMID:38627011 | DOI:10.2967/jnmt.123.266836 (Source: Journal of Nuclear Medicine Technology)
Source: Journal of Nuclear Medicine Technology - April 16, 2024 Category: Nuclear Medicine Authors: Dutsadee Suttho Source Type: research
The development and introduction of entrustable professional activities at 2 community-based chiropractic student preceptorship sites in the United States
CONCLUSION: This paper describes the development and introduction of EPAs at 2 community-based chiropractic preceptorship sites. Future research is needed to develop and standardize EPA use and assessment, and to evaluate outcomes associated with EPA use.PMID:38626920 | DOI:10.7899/JCE-23-26 (Source: The Journal of Chiropractic Education)
Source: The Journal of Chiropractic Education - April 16, 2024 Category: Complementary Medicine Authors: Jordan A Gliedt Kevin S Mathers Jeff King Michael J Schneider Michael R Wiles Source Type: research
CEPs suppress auxin signaling but promote cytokinin signaling to inhibit root growth in Arabidopsis
In this study, we examined prior research and elucidated the underlying molecular mechanisms. The results showed that both synthetic AtCEPs and overexpression of AtCEP5 markedly supressed primary root elongation and lateral root (LR) formation in Arabidopsis. Molecular biology and genetics elucidated how CEPs inhibit root growth by suppressing auxin signaling while promoting cytokinin signaling. In summary, this study elucidated the inhibitory effects of AtCEPs on Arabidopsis root growth and provided insights into their potential molecular mechanisms, thus enhancing our comprehension of CEP-mediated regulation of plant gro...
Source: Biochemical and Biophysical Research communications - April 16, 2024 Category: Biochemistry Authors: Yuwen Zhang Xingliang Duan Zhen Wang Yuanda Lv Weicong Qi Lun Li Le Luo Wei Xuan Source Type: research
Combined effects of azoxystrobin and oxytetracycline on rhizosphere microbiota of Arabidopsis thaliana
Environ Int. 2024 Apr 14;186:108655. doi: 10.1016/j.envint.2024.108655. Online ahead of print.ABSTRACTThe rhizosphere is one of the key determinants of plant health and productivity. Mixtures of pesticides are commonly used in intensified agriculture. However, the combined mechanisms underlying their impacts on soil microbiota remain unknown. The present study revealed that the rhizosphere microbiota was more sensitive to azoxystrobin and oxytetracycline, two commonly used pesticides, than was the microbiota present in bulk soil. Moreover, the rhizosphere microbiota enhanced network complexity and stability and increased c...
Source: Environment International - April 16, 2024 Category: Environmental Health Authors: Yuke Zhu Mingjing Ke Zhitao Yu Chaotang Lei Meng Liu Yaohui Yang Tao Lu Ning-Yi Zhou W J G M Peijnenburg Tao Tang Haifeng Qian Source Type: research
Use of inpatient palliative care in metastatic urethral cancer
CONCLUSION: IPC use in metastatic urethral cancer increased from a marginal rate of 5.8% to as high as 28%. Ideally, differences according to sex, metastatic site, and region should be addressed to improve IPC use rates.PMID:38627106 | DOI:10.1016/j.urolonc.2024.03.019 (Source: Urologic Oncology)
Source: Urologic Oncology - April 16, 2024 Category: Urology & Nephrology Authors: Carolin Siech Andrea Baudo Mario de Angelis Letizia Maria Ippolita Jannello Francesco Di Bello Jordan A Goyal Zhe Tian Fred Saad Shahrokh F Shariat Nicola Longo Luca Carmignani Ottavio de Cobelli Alberto Briganti S éverine Banek Philipp Mandel Luis A Klu Source Type: research
Mechanistic drivers of chromatin organization into compartments
Curr Opin Genet Dev. 2024 Apr 15;86:102193. doi: 10.1016/j.gde.2024.102193. Online ahead of print.ABSTRACTThe human genome is not just a simple string of DNA, it is a complex and dynamic entity intricately folded within the cell's nucleus. This three-dimensional organization of chromatin, the combination of DNA and proteins in the nucleus, is crucial for many biological processes and has been prominently studied for its intricate relationship to gene expression. Indeed, the transcriptional machinery does not operate in isolation but interacts intimately with the folded chromatin structure. Techniques for chromatin conforma...
Source: Current Opinion in Genetics and Development - April 16, 2024 Category: Genetics & Stem Cells Authors: Hannah L Harris M Jordan Rowley Source Type: research
Submicron aerosol pollution in Greater Cairo (Egypt): A new type of urban haze?
Environ Int. 2024 Mar 27;186:108610. doi: 10.1016/j.envint.2024.108610. Online ahead of print.ABSTRACTGreater Cairo, the largest megacity of the Middle East North Africa (MENA) region, is currently suffering from major aerosol pollution, posing a significant threat to public health. However, the main sources of pollution remain insufficiently characterized due to limited atmospheric observations. To bridge this knowledge gap, we conducted a continuous 2-month field study during the winter of 2019-2020 at an urban background site, documenting for the first time the chemical and physical properties of submicron (PM1) aerosol...
Source: Environment International - April 16, 2024 Category: Environmental Health Authors: Aliki Christodoulou Spyros Bezantakos Efstratios Bourtsoukidis Iasonas Stavroulas Michael Pikridas Konstantina Oikonomou Minas Iakovides Salwa K Hassan Mohamed Boraiy Mostafa El-Nazer Ali Wheida Magdy Abdelwahab Roland Sarda-Est ève Martin Rigler Giorgos Source Type: research
A parental burnout modelling based on perfectionism mediated through self-compassion in parents of students suffering from specific learning behavioral disorder
Acta Psychol (Amst). 2024 Apr 15;246:104227. doi: 10.1016/j.actpsy.2024.104227. Online ahead of print.ABSTRACTThe association between parental burnout and perfectionism, and whether and to what extent it is mediated by self-compassion, in case of mothers of children with Specific Learning Disorder (SLD) were rarely investigated in the related literature. To fill the gap felt, the present study aimed at providing a model for self-compassion, parental burnout, and perfectionism. The participants were 305 mothers of children with SLD, from Hamedan province, Iran, who had been referred to the relevant treatment centers between...
Source: Acta Psychologica - April 16, 2024 Category: Psychiatry & Psychology Authors: Hamid Jafarian Yasar Zabihullah Pirani Zeinab Ein Ali Source Type: research
