Efficacy of Diuretics in Kidney Disease
Conditions:   Chronic Kidney Disease;   End Stage Renal Disease Interventions:   Drug: Metolazone;   Drug: Placebo Sponsor:   Stanford University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 9, 2020 Category: Research Source Type: clinical trials

Ertugliflozin in Acute Heart Failure
Condition:   Acute Heart Failure Interventions:   Drug: Ertugliflozin;   Drug: Metolazone;   Drug: Placebo Sponsors:   Yale University;   Merck Sharp & Dohme Corp. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 19, 2020 Category: Research Source Type: clinical trials

Sequential Nephron Blockade in Acute Heart Failure
Condition:   Acute Heart Failure Interventions:   Drug: Metolazone;   Drug: Loop Diuretics Sponsors:   Policlinico Casilino ASL RMB;   Umberto I Hospital, Nocera Inferiore;   IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2019 Category: Research Source Type: clinical trials

Diuretic Effect of Metolazone Pre-dosing Versus Concurrent Dosing
Conditions:   Fluid Overload;   Heart Failure Acute Interventions:   Drug: Metolazone 60 minutes prior to furosemide;   Drug: Metolazone concurrently with furosemide Sponsor:   University of Maryland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 19, 2018 Category: Research Source Type: clinical trials

Prospective Comparison of Metolazone Versus Chlorothiazide for Acute Decompensated Heart Failure With Diuretic Resistance
Conditions:   Heart Failure;   Heart Failure With Reduced Ejection Fraction;   Heart Failure Acute;   Cardiovascular Diseases Interventions:   Drug: Metolazone Oral Tablet;   Drug: Chlorothiazide Injection Sponsor:   University of Virginia Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 2, 2018 Category: Research Source Type: clinical trials