Metoclopramide Injection, USP (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 23, 2017 Category: Drugs & Pharmacology Source Type: news

2016 Updated MASCC/ESMO consensus recommendations: Management of nausea and vomiting in advanced cancer
The aim of this paper was to develop a set of evidence-based guidelines for the management of different syndromes related to nausea and vomiting in advanced cancer. The authors found that the level of evidence in most studies is low, but conclude that the drug of choice is metoclopramide, with alternative options including haloperidol, levomepromazine, or olanzapine. For bowel obstruction, the recommendation is to use octreotide given alongside an antiemetic (haloperidol) and where octreotide is not an option to use an anticholinergic antisecretory agent. For opioid-induced nausea and vomiting, no recommendation could be m...
Source: Current Awareness Service for Health (CASH) - April 25, 2017 Category: Consumer Health News Source Type: news

Metoclopramide may be effective for clozapine-induced hypersalivation
Clozapine-induced hypersalivation is the most prevalent adverse effect experienced by patients treated with clozapine and negatively impacts on quality of life,1 with symptoms particularly prevalent at night-time. Pharmacotherapeutic strategies employed to date, based on multiple mechanisms including antimuscarinic agents and α-2 agonists have largely been associated with, at most, a minimal therapeutic effect.2 The development of strategies would thus be welcomed given the lack of effective treatment options, with such strategies hopefully being associated with an improvement in clinical outcome and perhaps also long-t e...
Source: Current Awareness Service for Health (CASH) - March 27, 2017 Category: Consumer Health News Source Type: news

Looking for relief, pregnant women turn to marijuana despite medical advice
According to data from the Centers for Disease Control and Prevention ’s National Vital Statistics Reports, more than one in five U.S. births now occur in states where marijuana is legal. That ’s triggered a concern among health professionals about the use of marijuana by pregnant women.Along with the broader availability of marijuana comes the perception that it is a harmless substance, health professionals say. But pregnant women, who may be seeking relief from a variety of ailments, should be aware of the potential health consequences of marijuana use.To understand how marijuana affects expectant mothers and infant...
Source: UCLA Newsroom: Health Sciences - March 2, 2017 Category: Universities & Medical Training Source Type: news

Reglan ODT (Metoclopramide Orally Disintegrating Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 30, 2016 Category: Drugs & Pharmacology Source Type: news

Metozolv ODT (Metoclopramide Hydrochloride Orally Disintegrating Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 30, 2016 Category: Drugs & Pharmacology Source Type: news

Reglan Injection (Metoclopramide Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 30, 2016 Category: Drugs & Pharmacology Source Type: news

Reglan (Metoclopramide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 8, 2016 Category: Drugs & Pharmacology Source Type: news

Treatment in carbon monoxide poisoning patients with headache: a prospective, multicenter, double-blind, controlled clinical trial - Ocak T, Tekin E, Basturk M, Duran A, Serinken M, Emet M.
BACKGROUND: There is a lack of specificity of the analgesic agents used to treat headache and underlying acute carbon monoxide poisoning. OBJECTIVE: To compare effectiveness of "oxygen alone" vs "metoclopramide plus oxygen" vs "metamizole plus oxyg... (Source: SafetyLit)
Source: SafetyLit - August 26, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Metoclopramide, Ibuprofen May Be Alternatives to Acetazolamide for Altitude Sickness Metoclopramide, Ibuprofen May Be Alternatives to Acetazolamide for Altitude Sickness
The antiemetic drug metoclopramide may reduce symptoms of acute mountain sickness (AMS) and serve as an alternative for those who cannot take the common first-line treatment acetazolamide, a new study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 8, 2016 Category: Consumer Health News Tags: Emergency Medicine News Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl Methadon...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

New AHS Consensus on Emergency Migraine ManagementNew AHS Consensus on Emergency Migraine Management
Intravenous metoclopramide and prochlorperazine, and subcutaneous sumatriptan, get the highest level of recommendation from a panel on acute treatment of migraine in the emergency department Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 17, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Metoclopramide and Diphenhydramine Blunt Pregnancy HeadachesMetoclopramide and Diphenhydramine Blunt Pregnancy Headaches
The two-drug combination is more expensive than codeine for reducing headaches in pregnant women, but is more effective and worth the cost, say researchers. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 15, 2015 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

How Long Before Gastroparesis Improves?
Discussion “[Gastroparesis] (GP) is a motor and sensory disorder of the stomach characterized by delayed gastric emptying in the absence of mechanical obstruction. Symptoms classically include nausea, vomiting, early satiety, bloating, postprandial fullness, abdominal pain and weight loss….GP is often not recognized and thus can remain untreated in children.” In the adult population, the age adjusted prevalence of GP is 9.6 (for men) and 37.8 (for women) per 100,000. There is no specific prevalence data available for children. It appears from some data that GP identification is rising and some data sugges...
Source: PediatricEducation.org - February 24, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Popular Morning Sickness Drug Safe in Pregnancy, Study Finds
Women taking metoclopramide can be reassured by the findings, expert says (Source: WebMD Health)
Source: WebMD Health - October 15, 2013 Category: Consumer Health News Source Type: news