The effect of a methadone reformulation on opioid agonist treatment outcomes: A population-based study in British Columbia, Canada, 2013 –14
The province of British Columbia, Canada, changed the existing oral anhydrous methadone solution to a 10-times more concentrated pre-mixed solution, Methadose ®, on February 1, 2014. We aimed to assess the immediate effects of the methadone reformulation on missed doses, days off methadone, changes in medication dosing and dispensations of opioids for pain, and hospitalizations and mortality among all people receiving treatment at or near the time of the change. (Source: Journal of Substance Abuse Treatment)
Source: Journal of Substance Abuse Treatment - December 27, 2021 Category: Addiction Authors: Emanuel Krebs, Natt Hongdilokkul, Laura M. Dale, Jeong E. Min, Kevin T. Schnepel, Hitoshi Shigeoka, Bohdan Nosyk Source Type: research

Prevalence of Heavy Alcohol Use Among People Receiving Methadone Following Change to Methadose.
CONCLUSIONS: Despite reported changes in opioid use patterns coinciding with the change, there appeared to be no effect of the methadone formulation change on heavy drinking in this setting. PMID: 28605308 [PubMed - as supplied by publisher] (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - June 13, 2017 Category: Addiction Tags: Subst Use Misuse Source Type: research