PARP Inhibitor-Based Triplet Promising in Endometrial Cancer
(MedPage Today) -- NEW ORLEANS -- A triplet combination of the PARP inhibitor olaparib (Lynparza), metronomic cyclophosphamide, and metformin was feasible and showed encouraging efficacy in elderly, heavily pretreated patients with recurrent... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 11, 2022 Category: Hematology Source Type: news
Yale researchers continue to unravel the mystery of metformin
Researchers have discovered a new mechanism through which metformin improves diabetes, revealing a potential therapeutic target for improved treatment. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 30, 2022 Category: Universities & Medical Training Source Type: news
Preconception Paternal Metformin Linked to Major Birth Defects
WEDNESDAY, March 30, 2022 -- Preconception paternal metformin treatment is associated with an increased risk for major birth defects, according to a study published online March 29 in the Annals of Internal Medicine.
Maarten J. Wensink, M.D., Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 30, 2022 Category: Pharmaceuticals Source Type: news
Metformin Prescriptions Linked to Sons & rsquo; Birth Defects
A new cohort study finds that boys whose fathers took the type 2 diabetes drug metformin three months before their conception were more likely to have a birth defect. (Source: The Scientist)
Source: The Scientist - March 29, 2022 Category: Science Tags: News & Opinion Source Type: news
Men's use of diabetes drug just before conception is linked to a 40% increase in birth defects, study finds
Metformin use by men in the three-month period before they conceived a child was linked to a 40% higher risk of birth defects in the offspring, according to a study published Monday in the journal Annals of Internal Medicine. (Source: CNN.com - Health)
Source: CNN.com - Health - March 29, 2022 Category: Consumer Health News Source Type: news
Metformin Use Linked to Birth Defects in Boys Metformin Use Linked to Birth Defects in Boys
Fathers taking the drug to control blood sugar were more likely to have sons with genitourinary anomalies.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - March 28, 2022 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
Study finds fathers taking diabetes drug while trying for a baby may raise risk of birth defects
A study of 1.1million newborns in Denmark found those whose fathers took metformin while trying to have a baby were three-times more likely to have a son with a genital birth defect. (Source: the Mail online | Health)
Source: the Mail online | Health - March 28, 2022 Category: Consumer Health News Source Type: news
Pfizer Recalls Some Blood Pressure Drugs, Citing Cancer Risk
The move follows recalls of other medications found to have higher levels of potential carcinogens. (Source: NYT Health)
Source: NYT Health - March 23, 2022 Category: Consumer Health News Authors: Christina Jewett Tags: Drugs (Pharmaceuticals) Recalls and Bans of Products Cancer Food and Drug Administration Pfizer Inc your-feed-healthcare Accuretic nitrosamine valsartan Valisure ranitidine N-nitrosodimethylamine ndma metformin benzene Source Type: news
Qternmet XR (Dapagliflozin, Saxagliptin, and Metformin Hydrochloride) - updated on RxList
Qternmet XR extended-release tablets for oral use contain dapagliflozin, saxagliptin, and metformin HCl. Learn about the uses for type 2 diabetes, side effects, usages, drug interactions, warnings, precautions, and more. (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 16, 2022 Category: Drugs & Pharmacology Source Type: news
How a widely used diabetes medication actually works
Yale researchers have elucidated the mechanism behind metformin and related type 2 diabetes drugs, and debunked a previously held theory on how they work. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 2, 2022 Category: Universities & Medical Training Source Type: news
FDA: Diabetes Medication Recall Due To Cancer Concerns, What Is Metformin?
This is a medication commonly used to control high blood sugar in those with type 2 diabetes. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 30, 2021 Category: Pharmaceuticals Authors: Bruce Y. Lee, Senior Contributor Tags: Healthcare /healthcare Innovation /innovation Science /science business pharma Source Type: news
More Lots of Diabetes Pill, Metformin, Recalled in US More Lots of Diabetes Pill, Metformin, Recalled in US
A further 33 lots of extended-release metformin 750 mg tablets have been voluntarily recalled in the US, by Viona, due to possible contamination with a cancer-causing chemical.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 30, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Alert Source Type: news
More Lots of Diabetes Pill Metformin Recalled in US More Lots of Diabetes Pill Metformin Recalled in US
A further 33 lots of extended-release metformin 750 mg tablets have been voluntarily recalled in the US, by Viona, due to possible contamination with a cancer-causing chemical.News Alerts (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - December 30, 2021 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Alert Source Type: news
Viona Pharmaceuticals Inc., Issues Voluntary Nationwide Recall of Metformin HCl Extended-Release Tablets, USP 750 mg, Due to the Detection of N-Nitrosodimethylamine (NDMA) Impurity
Cranford, New Jersey, Viona Pharmaceuticals Inc., is voluntarily recalling thirty three (33) lots of Metformin Hydrochloride Extended-Release Tablets, USP 750 mg to the retail level. Reason for the recall is an Out of specification result observed for the said product, Lot number M008132, “N-nitroso (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 28, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news
EU Green Light for Finerenone for CKD, Growth Hormone for Kids EU Green Light for Finerenone for CKD, Growth Hormone for Kids
Positive opinions issued for branded somatrogon and finerenone and for generic versions of sitagliptin/metformin hydrochloride and sapropterin.International Approvals (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - December 20, 2021 Category: Transplant Surgery Tags: Diabetes & Endocrinology News Alert Source Type: news
