Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin
Conditions:   Malignant Pleural Mesotheliomas (Mpm);   Malignant Pleural Effusions (Mpe);   Epithelial Tumors, Malignant;   Pleural Effusions, Malignant;   Mesothelin (Msln) Interventions:   Procedure: Cytoreductive surgery;   Drug: LMB-100;   Diagnostic Test: Immunohistochemical Assay for Mesothelin Sponsor:   National Cancer Institute (NCI) Not yet recruiting (Source:
Source: - May 17, 2022 Category: Research Source Type: clinical trials

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers
Conditions:   Microsatellite High Cancers;   Peritoneal Mesothelioma;   Extrapulmonary High Grade;   Neuroendocrine Carcinomas;   Cervical Carcinoma;   Hodgkin's Lymphoma;   Pleural Mesothelioma;   Small Cell Lung Cancer Intervention:   Drug: XmAb20717 Sponsor:   M.D. Anderson Cancer Center Not yet recruiting (Source:
Source: - April 20, 2022 Category: Research Source Type: clinical trials