Dipeptidyl peptidase 4 inhibitors vs. metformin for new-onset dementia: a propensity score-matched cohort study
CONCLUSION: In this real-world study, we found that DPP4 inhibitors presented an association with a lower risk of dementia in individuals with type 2 diabetes than metformin, particularly in older people and those without diabetes-related comorbidities.PMID:38652239 | DOI:10.1210/clinem/dgae281 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 23, 2024 Category: Endocrinology Authors: Siyang Liu Heng Wan Sheng Nie Huanyi Cao Lan Liu Hua Liang Hong Xu Bicheng Liu Chunbo Chen Huafeng Liu Qiongqiong Yang Hua Li Yaozhong Kong Guisen Li Qijun Wan Yan Zha Ying Hu Gang Xu Yongjun Shi Yilun Zhou Guobin Su Ying Tang Mengchun Gong Aixin Guo Jian Source Type: research
Cochlear implantation in patients with < em > Streptococcus suis < /em > meningitis: clinical characteristics and postoperative evaluation
CONCLUSIONS AND SIGNIFICANCE: It is recommended for S. suis meningitis CI candidates to undergo CI promptly after controlling infection, preferably within four to six weeks. CI users with S. suis meningitis tend to exhibit suboptimal hearing rehabilitation outcomes, possibly associated with the more severe damage on spiral ganglion cells after S. suis meningitis.PMID:38651889 | DOI:10.1080/00016489.2024.2323650 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 23, 2024 Category: ENT & OMF Authors: Zhuoyi Chen Minqian Gao Xiaying Huang Xianghui Li Xiaotong Huang Yongkang Ou Yiqing Zheng Haidi Yang Source Type: research
Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Rev Endocr Metab Disord. 2024 Apr 23. doi: 10.1007/s11154-024-09882-0. Online ahead of print.ABSTRACTProgesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, progesterone contributes to the control of luteinizing hormone and follicle-stimulating hormone secretion and their pulsatility, via its receptors on the kisspeptin, neurokinin B, and dynorphin neurons in the hypothalamus. Progesterone together with estradiol controls the cyclic changes of proliferation and decidualization of the endometrium; exerts anti-mitogenic actions on endometrial epithelial cells; r...
Source: ENDOCR REV - April 23, 2024 Category: Endocrinology Authors: Eleni Memi Polina Pavli Papagianni Maria Nikolaos Vrachnis George Mastorakos Source Type: research
Electromagnetic Modulation of Cell Behavior: Unraveling the Positive Impacts in a Comprehensive Review
Ann Biomed Eng. 2024 Apr 23. doi: 10.1007/s10439-024-03519-8. Online ahead of print.ABSTRACTThere are numerous effective procedures for cell signaling, in which humans directly transmit detectable signals to cells to govern their essential behaviors. From a biomedical perspective, the cellular response to the combined influence of electrical and magnetic fields holds significant promise in various domains, such as cancer treatment, targeted drug delivery, gene therapy, and wound healing. Among these modern cell signaling methods, electromagnetic fields (EMFs) play a pivotal role; however, there remains a paucity of knowled...
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Amirhossein Bahmanpour Seyed Majid Ghoreishian Azadeh Sepahvandi Source Type: research
Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Rev Endocr Metab Disord. 2024 Apr 23. doi: 10.1007/s11154-024-09882-0. Online ahead of print.ABSTRACTProgesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, progesterone contributes to the control of luteinizing hormone and follicle-stimulating hormone secretion and their pulsatility, via its receptors on the kisspeptin, neurokinin B, and dynorphin neurons in the hypothalamus. Progesterone together with estradiol controls the cyclic changes of proliferation and decidualization of the endometrium; exerts anti-mitogenic actions on endometrial epithelial cells; r...
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Eleni Memi Polina Pavli Papagianni Maria Nikolaos Vrachnis George Mastorakos Source Type: research
Elevated gut microbiota metabolite bile acids confer protective effects on clinical prognosis in ischemic stroke patients
CONCLUSION: Serum TBA is an independent risk factor for disability and poor functional outcomes after AIS or TIA, and exerts a protective effects on brain.PMID:38650617 | PMC:PMC11033300 | DOI:10.3389/fnins.2024.1388748 (Source: Atherosclerosis)
Source: Atherosclerosis - April 23, 2024 Category: Cardiology Authors: Zhaobin Wang Jing Li Yingxin Xu Ye Liu Zhe Zhang Qin Xu Jinxi Lin Yong Jiang Yongjun Wang Jing Jing Anxin Wang Xia Meng Source Type: research
Adaptive radiotherapy for head and neck cancer: Pitfalls and possibilities from the radiation oncologist's point of view
CONCLUSION: Although based on mainly non-randomized and retrospective trials, there is accumulating evidence that ART has the potential to reduce toxicity and improve quality of life and tumor control in HNC patients treated with RT. However, several questions remain regarding accurate patient selection, the ideal frequency and timing of replanning, and the appropriate way for image registration and dose calculation. Well-designed randomized prospective trials, with a predetermined protocol for both image registration and dose summation, are urgently needed to further investigate the dosimetric and clinical benefits of ART...
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Sandra Nuyts Heleen Bollen Avrahram Eisbruch Primoz Strojan William M Mendenhall Sweet Ping Ng Alfio Ferlito Source Type: research
Reducing False-Positives Due to Urinary Stagnation in the Prostatic Urethra on 18F-DCFPyL PSMA PET/CT With MRI
CONCLUSIONS: Stagnated urine within the prostatic urethra is a potential confounding factor on PSMA PET scans. Integrating PET imaging with T2W MRI can mitigate false-positive calls, especially as PSMA PET/CT continues to gain traction in diagnosing localized prostate cancer.PMID:38651785 | DOI:10.1097/RLU.0000000000005220 (Source: Cancer Control)
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: David G Gelikman Esther Mena Liza Lindenberg William S Azar Nityam Rathi Enis C Yilmaz Stephanie A Harmon Kyle C Schuppe Jessica Y Hsueh Hannah Huth Bradford J Wood Sandeep Gurram Peter L Choyke Peter A Pinto Baris Turkbey Source Type: research
Transversus Abdominis Plane Block versus Epidural Anesthesia for Pain Management Post-Caesarean Delivery: A Pilot Study
CONCLUSION: The TAP block proves advantageous in mitigating postoperative pain for women post-caesarean delivery, particularly in the initial 6 postpartum hours. This relief promotes early mother-infant bonding and facilitates breastfeeding.PMID:38650746 | PMC:PMC11033210 | DOI:10.2147/LRA.S444947 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - April 23, 2024 Category: Anesthesiology Authors: Jorge Emilio Salazar-Fl órez Leidy Tatiana Arenas-Cardona Ninemy Marhx Eduardo L ópez-Guerrero Ángela Patricia Echeverri-Rendón Luz Stella Giraldo-Cardona Source Type: research
Effects of Recreational Cannabis Legalization on Mental Health: Scoping Review
CONCLUSIONS: Clinicians, researchers, and policy makers need to collaborate to address the research gaps and to develop evidence-based policies that reflect a thorough understanding of the effects associated with RCL.PMID:38650490 | DOI:10.1176/appi.ps.20230434 (Source: Psychiatric Services)
Source: Psychiatric Services - April 23, 2024 Category: Psychiatry Authors: Alexandra Fortier In ès Zouaoui Alexandre Dumais St éphane Potvin Source Type: research
Prevalence of Opioid Use Disorder and Opioid Overdose Rates Among People With Mental Illness
CONCLUSIONS: These findings underscore the importance of providing opioid use disorder screening and treatment for patients receiving psychiatric services.PMID:38650488 | DOI:10.1176/appi.ps.20230338 (Source: Psychiatric Services)
Source: Psychiatric Services - April 23, 2024 Category: Psychiatry Authors: Qingxian Chen Manesh Gopaldas Felipe Castillo Emily Leckman-Westin Edward V Nunes Frances R Levin Molly T Finnerty Source Type: research
ChatGPT in mental health care
CONCLUSION: ChatGPT has the potential to significantly transform MHC, from streamlining administrative tasks to enhancing therapeutic contact. Aspects such as privacy and information accuracy should be central in its implementation. While current scientific evidence is still quite limited, ChatGPT already offers possibilities that should now be utilized by healthcare professionals. It is crucial that therapists form an opinion about ChatGPT, and institutions should be willing to invest in this innovative technology.PMID:38650514 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - April 23, 2024 Category: Psychiatry Authors: B C van der Meer Source Type: research
Aftershocks; about the psychological consequences of gas extraction in Groningen
CONCLUSION: The knowledge available within psychiatry and psychology about the development and treatment of psychological complaints should play a role in researching and improving the well-being and the mental health of those affected by the gas extraction problem, now and in the future.PMID:38650513 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - April 23, 2024 Category: Psychiatry Authors: Y Meesters R A Schoevers Source Type: research
Experiential acceptance in the treatment of complex somatic symptom disorder
CONCLUSION: The current study demonstrates that an increase in experiential acceptance goes hand in hand with an improvement in mental health and general health perception. These results indicate the potential importance of acceptance-based treatment in patients with complex SSD. Experimental research with more frequent measurements is needed to test a temporal relationship between (first) increased acceptance and (then) improved quality of life.PMID:38650510 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - April 23, 2024 Category: Psychiatry Authors: P J Herremans J F van Eck van der Sluijs R Geenen J H Houtveen Source Type: research
A qualitative study of shared decision making related to psychotropic drugs in adolescence
CONCLUSION: When we ask adolescents about their experience with SDM, we can learn the following:- Involve parents, but always tailor this to the individual adolescent and his context. – Put the adolescent at the center. – Dwell on the adolescent’s view on psychotropic drugs.PMID:38650508 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - April 23, 2024 Category: Psychiatry Authors: S Pillen I Glazemakers S Bal Source Type: research
