Transfer learning and self-distillation for automated detection of schizophrenia using single-channel EEG and scalogram images
In this study, our main goal is to develop an optimized system that can achieve automatic diagnosis of SZ with minimal input information. To optimize the system, we adopted a strategy of using single-channel EEG signals and integrated knowledge distillation and transfer learning techniques into the model. This approach was designed to improve the performance and efficiency of our proposed method for SZ diagnosis. Additionally, to leverage the pre-trained models effectively, we converted the EEG signals into images using Continuous Wavelet Transform (CWT). This transformation allowed us to harness the capabilities of pre-tr...
Source: Australasian Physical and Engineering Sciences in Medicine - April 23, 2024 Category: Biomedical Engineering Source Type: research
Correction to: Psychometric Evaluation of the MENQOL Instrument in Women Experiencing Vasomotor Symptoms Associated with Menopause
(Source: Advances in Therapy)
Source: Advances in Therapy - April 23, 2024 Category: Drugs & Pharmacology Source Type: research
Middle meningeal artery embolization associated with reduced chronic subdural hematoma volume and midline shift in the acute postoperative period
Conclusion
MMA embolization is safe and effective for the management of cSDH and is associated with significant reductions in hematoma volume and midline shift in the immediate postoperative period. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Catapano, J. S., Koester, S. W., Hanalioglu, S., Farhadi, D. S., Naik, A., Hartke, J. N., Tunc, O., Winkler, E. A., Chang, S. W., Lawton, M. T., Jadhav, A. P., Ducruet, A. F., Albuquerque, F. C. Tags: Hemorrhagic stroke Source Type: research
Clot composition and recanalization outcomes in mechanical thrombectomy
Conclusions
Despite the lack of correlation between clot histology and FPE, our study adds to the growing evidence supporting the notion that clot composition influences recanalization treatment strategy outcomes. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Nogueira, R. G., Pinheiro, A., Brinjikji, W., Abbasi, M., Al-Bayati, A. R., Mohammaden, M. H., Souza Viana, L., Ferreira, F., Abdelhamid, H., Bhatt, N. R., Kvamme, P., Layton, K. F., Delgado Almandoz, J. E., Hanel, R. A., Mendes Pereira, V., Almekhlafi, M Tags: Ischemic stroke Source Type: research
Causal relationships of Helicobacter pylori and related gastrointestinal diseases on Type 2 diabetes: Univariable and Multivariable Mendelian randomization
ConclusionOur study found that H. pylori IgG antibody, H. pylori GroEL antibody, gastroduodenal ulcer and chronic gastritis are all related to t T2DM, and blood glucose level and obesity mediate the development of H. pylori GroEL antibody and gastroduodenal ulcer on T2DM, respectively. These findings may inform new prevention and intervention strategies for T2DM. (Source: PLoS One)
Source: PLoS One - April 23, 2024 Category: Biomedical Science Authors: Mei Sun Source Type: research
The PROMIS-16 reproduces the PROMIS-29 physical and mental health summary scores accurately in a probability-based internet panel
ConclusionThe PROMIS-16 provides similar estimates of the PROMIS-29 physical and mental health summary scores. The high reliability of these scores indicates they are accurate enough for use with individual patients. (Source: Quality of Life Research)
Source: Quality of Life Research - April 23, 2024 Category: Health Management Source Type: research
Genes, Vol. 15, Pages 529: SNP and Structural Study of the Notch Superfamily Provides Insights and Novel Pharmacological Targets against the CADASIL Syndrome and Neurodegenerative Diseases
In this study, an in silico analysis of polymorphisms and mutations in human Notch family members that lead to neurodegenerative diseases was performed in order to investigate the correlations among Notch family proteins and neurodegenerative diseases. Particular emphasis was placed on the study of mutations in the Notch3 protein and the structure analysis of the mutant Notch3 protein that leads to the manifestation of the CADASIL syndrome in order to spot possible conserved mutations and interpret the effect of these mutations in the Notch3 protein structure. Conserved mutations of cysteine residues may be candidate pharm...
Source: Genes - April 23, 2024 Category: Genetics & Stem Cells Authors: Louis Papageorgiou Lefteria Papa Eleni Papakonstantinou Antonia Mataragka Konstantina Dragoumani Dimitrios Chaniotis Apostolos Beloukas Costas Iliopoulos Erik Bongcam-Rudloff George P. Chrousos Sofia Kossida Elias Eliopoulos Dimitrios Vlachakis Tags: Article Source Type: research
An important contributing factor in dry eye disease: somatization
ConclusionSomatization should be considered in patients with DED with chronic ocular surface symptoms. Presence of subjective symptoms resistant to treatment may be an indicator of somatization. (Source: International Ophthalmology)
Source: International Ophthalmology - April 23, 2024 Category: Opthalmology Source Type: research
Do the management and functional outcomes of the surgically treated spinal fractures change in suicidal jumpers?
ConclusionPsychiatric disorders are more common in patients in the suicidal jumpers. The presence of underlying psychiatric problems adversely affects the postoperative functional outcomes of patients with surgically treated spinal fractures. A multidisciplinary approach together with raising awareness in this way can improve the clinical outcomes after orthopedic treatment, even if there is physical disability. (Source: European Spine Journal)
Source: European Spine Journal - April 23, 2024 Category: Orthopaedics Source Type: research
Subretinal transient hyporeflectivity in neovascular age-related macular degeneration and its response to a loading phase of aflibercept: PRECISE report 4
Eye, Published online: 23 April 2024; doi:10.1038/s41433-024-03087-0Subretinal transient hyporeflectivity in neovascular age-related macular degeneration and its response to a loading phase of aflibercept: PRECISE report 4 (Source: Eye)
Source: Eye - April 23, 2024 Category: Opthalmology Authors: Andrea Montesel Raheeba Pakeer Muhammed Swati Chandak Dimitrios Kazantzis Sridevi Thottarath Shruti Chandra Victor Chong Benjamin J. L. Burton Geeta Menon Ian Pearce Martin McKibbin Ajay Kotagiri James Talks Anna Grabowska Faruque Ghanchi Richard Gale And Source Type: research
Infections in preschool and school-aged children are driving the recent rise in pertussis in China
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Yahong Hu, Mengyang Guo, Kaihu Yao Source Type: research
Changing clinical characteristics of pediatric inpatients with pneumonia during COVID-19 pandamic: a retrospective study
This study aimed to compare the pathogen, allergen and micronutrient characteristics of pediatric inpatien... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 23, 2024 Category: Pediatrics Authors: Mengxue Chen, Yabing Zhou, Shengjie Jin, Shasha Bai, Xiaoyu Tang, Quanhua Liu, Liwei Wang, Ruoxu Ji, Haipei Liu, Wenwei Zhong, Yi Chen, Dingzhu Fang, Jianhua Zhang and Li Hua Tags: Research Source Type: research
Recent United States Developments in the Pharmacological Treatment of Dry Eye Disease
AbstractDry eye disease (DED) can arise from a variety of factors, including inflammation, meibomian gland dysfunction (MGD), and neurosensory abnormalities. Individuals with DED may exhibit a range of clinical signs, including tear instability, reduced tear production, and epithelial disruption, that are driven by different pathophysiological contributors. Those affected often report a spectrum of pain and visual symptoms that can impact physical and mental aspects of health, placing an overall burden on an individual ’s well-being. This cumulative impact of DED on an individual’s activities and on society underscores...
Source: Drugs - April 23, 2024 Category: Drugs & Pharmacology Source Type: research
VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane
Oncogene, Published online: 23 April 2024; doi:10.1038/s41388-024-03038-9VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane (Source: Oncogene)
Source: Oncogene - April 23, 2024 Category: Cancer & Oncology Authors: Qing-Qing Li Meng Guo Guang-Huan He Kai-Hua Xi Mei-Yi Zhou Rong-Yi Shi Guo-Qiang Chen Source Type: research
Cancers, Vol. 16, Pages 1625: The Use of Glucagon-like Peptide-1 Receptor Agonists in Patients with Type 2 Diabetes Mellitus Does Not Increase the Risk of Pancreatic Cancer: A U.S.-Based Cohort Study
Conclusion: The use of GLP-1 RAs in patients with type 2 diabetes mellitus (T2DM) does not appear to substantially elevate the risk of pancreatic cancer; in fact, it may potentially exert a protective effect. (Source: Cancers)
Source: Cancers - April 23, 2024 Category: Cancer & Oncology Authors: Mark Ayoub Carol Faris Tajana Juranovic Harleen Chela Ebubekir Daglilar Tags: Article Source Type: research
