New Solid Forms of Tetrahydrocurcumin with Improved Solubility
CrystEngComm, 2024, Accepted Manuscript DOI: 10.1039/D4CE00259H, PaperFanyu Tian, Mengyuan Xia, Hao Wang, Bingrui Zhang, Zhenfeng Ding, Xiaoyi Rong, Bingqing Zhu, Xuefeng Mei Tetrahydrocurcumin (THC), one of the active metabolites of curcumin, possesses pharmacological activities similar to those of curcumin, such as hypoglycemic, hypolipidemic and antioxidant effects. However, poor water solubility of THC... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - CrystEngComm latest articles)
Source: RSC - CrystEngComm latest articles - April 25, 2024 Category: Chemistry Authors: Fanyu Tian Source Type: research
Letter to the editor regarding “Associations between paraspinal muscle characteristics and spinal curvature in conservatively treated adolescent idiopathic scoliosis: a systematic review” by Chan et al.
We read with high interest the study by Chan and colleagues about the muscle characteristics in scoliosis and their relationships with the curve features. The authors conducted a systematic review and found that the paraspinal muscles on the concavity presented different important alterations [1]. The results of this work are very important, especially for supporting the studies about rehabilitation in scoliosis. The application of quantitative measures, like the ones mentioned in the review, deserves a lot of attention because they allow precise calculations able to sustain valid reasonings. (Source: The Spine Journal)
Source: The Spine Journal - April 25, 2024 Category: Orthopaedics Authors: Daniele Coraci, Maria Chiara Maccarone, Giorgio Simioni, Lisa Ragazzo, Stefano Masiero Tags: Letters to the Editor Source Type: research
Neuronal intranuclear inclusion disease with cerebellar white matter tau uptake and incidental meningioma
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 24, 2024 Category: Nuclear Medicine Source Type: research
Biocatalytic Asymmetric Ring-Opening of meso-Epoxides to Enantiopure Cyclic trans- β-Amino Alcohols Involving a Key Amine Transaminase
Green Chem., 2024, Accepted Manuscript DOI: 10.1039/D4GC00827H, Paper Jingqi Zhang, Hang Gao, Lili Gao, Mengyi Chen, Shuangping Huang, Jiandong Zhang Chiral cyclic β-amino alcohols are vital building blocks for the synthesis of numerous pharmaceuticals and bioactive molecules. Asymmetric ring-opening of cyclic meso-epoxides is a straightforward and appealing method for their... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Green Chem. latest articles)
Source: RSC - Green Chem. latest articles - April 24, 2024 Category: Chemistry Authors: Jingqi Zhang Source Type: research
Novel dual near-infrared fluorescent probe for bioimaging and visualization of viscosity in acute alcoholic liver injury
Chem. Commun., 2024, Accepted Manuscript DOI: 10.1039/D4CC01222D, CommunicationRuonan Wang, Xucong Zhou, Bingxue Li, Ru Ding, Jingqian Han, Ying Wang, Aixia Meng, Jin Zhou A dual NIR fluorescent probe Cy-ND is developed for viscosity sensing with λex/em = 766/806nm, making Cy-ND apt for biological analysis, whose response is validated through DFT and TDDFT computations.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - April 24, 2024 Category: Chemistry Authors: Ruonan Wang Source Type: research
How do different intraoral scanners and milling machines affect the fit and fatigue behavior of lithium disilicate and resin composite endocrowns?
J Mech Behav Biomed Mater. 2024 Apr 18;155:106557. doi: 10.1016/j.jmbbm.2024.106557. Online ahead of print.ABSTRACTThe aim of this in vitro study was to evaluate the effect of the combinations of two different intraoral scanners (IOS), two milling machines, and two restorative materials on the marginal/internal fit and fatigue behavior of endocrowns produced by CAD-CAM. Eight groups (n= 10) were considered through the combination of TRIOS 3 (TR) or Primescan (PS) IOS; 4-axes (CR; CEREC MC XL) or 5-axes (PM; PrograMill PM7) milling machines; and lithium disilicate (LD; IPS e.max CAD) or resin composite (RC; Tetric CAD) rest...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 24, 2024 Category: Materials Science Authors: Rafaela Oliveira Pilecco Lucas Saldanha da Rosa Andrea Baldi Renan Vaz Machry Jo ão Paulo Mendes Tribst Luiz Felipe Valandro Cornelis Johannes Kleverlaan Nicola Scotti Gabriel Kalil Rocha Pereira Source Type: research
Graduate medical education success coaching for residents and fellows: a single-institution real-world experience
We report our three-year experience of a GME success coaching program that aims to help trainees reach their full potential by addressing various areas of medical knowledge, clinical skills, efficiency, interpersonal skills and communication, professionalism, and mental health and well-being. The majority of participants (87%) were identified by themselves, their program director, and/or the GME coaches to have more than one area of need. The majority (79%) of referrals were identified by the coaches to have additional needs to the reasons for referral. We provide a framework for implementation of a GME coaching program an...
Source: Medical Education Online - April 24, 2024 Category: Universities & Medical Training Authors: Charles Redman Catherine G Chung Daniel McFarlane Alexa Meara Aslam Ejaz Source Type: research
Improving connections to early childhood systems of care via a universal home visiting program in Massachusetts
Child Youth Serv Rev. 2023 Jul;150. doi: 10.1016/j.childyouth.2023.106995.ABSTRACTWelcome Family is a universal, short-term nurse home visiting program designed to promote optimal maternal and infant physical and mental well-being and provide an entry point into the early childhood system of care to all families with newborns up to 8 weeks old living in defined communities in Massachusetts. The present study examines whether: 1) Welcome Family meets its goal of successfully connecting families to two early childhood programs-evidence-based home visiting (EBHV) and early intervention (EI)-relative to families with similar b...
Source: Children and Youth Services Review - April 24, 2024 Category: Child Development Authors: Chie Kotake Rebecca C Fauth Katie Stetler Jessica L Goldberg Christine F Silva Susan E Manning Source Type: research
Stressful life events and prenatal representations of the child
Attach Hum Dev. 2024 Apr 24:1-17. doi: 10.1080/14616734.2024.2345242. Online ahead of print.ABSTRACTCaregivers' mental representations of their children can be assessed prenatally and are prospectively associated with later caregiving quality and caregiver-child attachment. Compared to balanced, distorted or disengaged representations are linked to insecure caregiver-child attachments. The present study explored factors (i.e. stressful life experiences and positive experiences) that may be linked to risk for distorted and disengaged representations. We used a brief version of the Prenatal Working Model of the Child Intervi...
Source: Attachment and Human Development - April 24, 2024 Category: Child Development Authors: Lauren G Bailes Abigail Blum Whitney Barnett Hannah Piersiak Sydney Takemoto Brooke Fleming Caelan Alexander Kathryn L Humphreys Source Type: research
Impact of on-call shifts on working memory and the role of burnout, sleep, and mental well-being in trainee physicians
CONCLUSION: Working more on-call shifts is associated with compromised WM. Trainee physicians who experienced more depressive symptoms and burnout had worse WM.PMID:38656827 | DOI:10.1080/00325481.2024.2347195 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 24, 2024 Category: Internal Medicine Authors: Abeer F Almarzouki Source Type: research
Coronavirus Anxiety, COVID Anxiety Syndrome and Mental Health: A Test Among Six Countries During March 2021
Clin Psychol Psychother. 2024 Mar-Apr;31(2):e2988. doi: 10.1002/cpp.2988.ABSTRACTThe negative impact of the COVID-19 pandemic on mental health outcomes is widely documented. Specifically, individuals experiencing greater degrees of severity in coronavirus anxiety have demonstrated higher levels of generalized anxiety, depression and psychological distress. Yet the pathways in which coronavirus anxiety confers vulnerability are not well known. The present investigation sought to address this gap in the scientific literature by testing the indirect effect of the COVID-19 anxiety syndrome, which centres on the function of det...
Source: Clinical Psychology and Psychotherapy - April 24, 2024 Category: Psychiatry Authors: Michael J Zvolensky Jafar Bakhshaie Brooke Y Redmond Tanya Smit Ana V Nik čević Marcantonio M Spada Walter Distaso Source Type: research
Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research
Illness Anxiety Disorder and Distress among Female Medical and Nursing Students
CONCLUSION: The highlights that medical and nursing students are susceptible to developing anxiety-related disorders and distress that may have negative impacts on their academic achievements and future careers. Both nursing and medical faculty should help in identifying strategies to support the students' mental health and well-being.PMID:38655550 | PMC:PMC11037515 | DOI:10.2174/0117450179277976231115070100 (Source: Clinical Practice and Epidemiology in Mental Health)
Source: Clinical Practice and Epidemiology in Mental Health - April 24, 2024 Category: Psychiatry Authors: Sana Hawamdeh Fatchima L Moussa Sami Al-Rawashdeh Sajidah Al Hawamdih Mahaman L Moussa Source Type: research
Effect of Psychosocial Interventions on Cancer's Caregiver Quality of Life: Meta-analysis
CONCLUSION: According to this meta-analysis, The psychological intervention program positively affected cancer caregiver's quality of life. Further randomised controlled trials are required to prove that psychological interventional programs are successful strategies for improving cancer caregiver's quality of life.PMID:38655551 | PMC:PMC11037513 | DOI:10.2174/17450179-v19-e230927-2022-HT14-4336-1 (Source: Clinical Practice and Epidemiology in Mental Health)
Source: Clinical Practice and Epidemiology in Mental Health - April 24, 2024 Category: Psychiatry Authors: C Vasantha Kalyani Kusum K Rohilla Pratima Gupta Amit Gupta Sweety Gupta Source Type: research
First Onset in Adulthood of Mental Disorders: Exposure to War < em > vs < /em > . Non-war Childhood Adversities: A National Study
CONCLUSION: Childhood traumata are not equal in predicting the first onset of mood and anxiety disorders into adulthood. Family malfunctioning looks to carry the longest such risk and war more of shorter immediate effects. This might change though with re-exposure to war in adulthood which might unravel dormant vulnerability.PMID:38655552 | PMC:PMC11037514 | DOI:10.2174/0117450179216651231106072824 (Source: Clinical Practice and Epidemiology in Mental Health)
Source: Clinical Practice and Epidemiology in Mental Health - April 24, 2024 Category: Psychiatry Authors: Elie Karam Josleen Al Barathie Dahlia Saab Aimee Nasser Karam John Fayyad Source Type: research
