A prospective randomised controlled trial of mechanical axis with soft tissue release balancing vs functional alignment with bony resection balancing in total knee replacement —a study using Stryker Mako robotic arm-assisted technology
This study is unique in that it leverages an advanced analytics tool to assist the surgeon in achieving balance. Both alignment techniques will be executed with high precision using the CT-based robotic arm-assisted surgery system which will minimise surgical variation. This trial design will help determine if FA delivers superior outcomes for patients.Trial registrationAustralia and New Zealand Clinical Trials Registry (ANZCTR),ACTRN12620000009910. Registered on 9 January 2020. ClinicalTrials.gov,NCT04600583. Registered on 29 September 2020. (Source: Trials)
Source: Trials - July 20, 2022 Category: Research Source Type: clinical trials

The effect of Bushen Culuan Decoction on anovulatory infertile women among 6 different diseases: a study protocol for a randomized, double-blinded, positively controlled, adaptive multicenter clinical trial
This study will evaluate the effectiveness and safety of Bushen Culuan Decoction for anovulatory infertility caused by six diseases, including anovulatory abnormal uterine bleeding, polycystic ovarian syndrome, hyperprolactinemia, luteinized unruptured follicle syndrome, corpus luteum insufficiency, and premature ovarian insufficiency.MethodsThis is a randomized, double-blinded, double-dummy, parallel, positively controlled, adaptive, multicenter clinical trial. All participants will be randomly allocated by a central randomization system to the treatment group or the control group in a 1:1 ratio. The treatment group will ...
Source: Trials - July 8, 2022 Category: Research Source Type: clinical trials

The effect of sesame oil consumption compared to sunflower oil on lipid profile, blood pressure, and anthropometric indices in women with non-alcoholic fatty liver disease: a randomized double-blind controlled trial
ConclusionsThe present clinical trial revealed that SO and SFO may not differently affect anthropometric indices, SBP, and lipid profile except for TC/HDL-C. In addition, SO may be effective in improvement of DBP and TC/HDL-C compared to the SFO group.Trial registrationEthical approval of this trial was obtained at Isfahan University of Medical Sciences with the reference number of IR.MUI.RESEARCH.REC.1399.548  (https://ethics.research.ac.ir/ProposalCertificateEn.php?id=158942&Print=true&NoPrintHeader=true&NoPrintFooter=true&NoPrintPageBorder=true&LetterPrint=true), and it was registered before the sta...
Source: Trials - July 8, 2022 Category: Research Source Type: clinical trials

Study of AD981 Versus Placebo in Obesity Hypoventilation Syndrome
Condition:   Obesity Hypoventilation Syndrome (OHS) Interventions:   Drug: AD981;   Other: Placebo Sponsors:   Istituto Auxologico Italiano;   Apnimed Inc.;   VIS Ethic Research Srl;   University of Florence;   STM Pharma PRO srl Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 7, 2022 Category: Research Source Type: clinical trials