Assessing the appropriateness of community-based antibiotic prescribing in Alberta, Canada, 2017-2020, using ICD-9-CM codes: a cross-sectional study
CMAJ Open. 2023 Jul 4;11(4):E579-E586. doi: 10.9778/cmajo.20220114. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Antimicrobial resistance is a rising threat to human health, and, with up to 90% of antibiotics prescribed in the community, it is critical to examine Canadian antibiotic stewardship practices in outpatient settings. We carried out a large-scale analysis of appropriateness in community-based prescribing of antibiotics to adults in Alberta, reporting on 3 years of data from physicians practising in the province.METHODS: The study cohort was composed of all adult (age 18-65 yr) Alberta residents who filled at least 1 an...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Myles Leslie Raad Fadaak Brendan Cord Lethebe Jessie Hart Szostakiwskyj Source Type: research
Assessing the appropriateness of community-based antibiotic prescribing in Alberta, Canada, 2017-2020, using ICD-9-CM codes: a cross-sectional study
CMAJ Open. 2023 Jul 4;11(4):E579-E586. doi: 10.9778/cmajo.20220114. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Antimicrobial resistance is a rising threat to human health, and, with up to 90% of antibiotics prescribed in the community, it is critical to examine Canadian antibiotic stewardship practices in outpatient settings. We carried out a large-scale analysis of appropriateness in community-based prescribing of antibiotics to adults in Alberta, reporting on 3 years of data from physicians practising in the province.METHODS: The study cohort was composed of all adult (age 18-65 yr) Alberta residents who filled at least 1 an...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Myles Leslie Raad Fadaak Brendan Cord Lethebe Jessie Hart Szostakiwskyj Source Type: research
Assessing the appropriateness of community-based antibiotic prescribing in Alberta, Canada, 2017-2020, using ICD-9-CM codes: a cross-sectional study
CMAJ Open. 2023 Jul 4;11(4):E579-E586. doi: 10.9778/cmajo.20220114. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Antimicrobial resistance is a rising threat to human health, and, with up to 90% of antibiotics prescribed in the community, it is critical to examine Canadian antibiotic stewardship practices in outpatient settings. We carried out a large-scale analysis of appropriateness in community-based prescribing of antibiotics to adults in Alberta, reporting on 3 years of data from physicians practising in the province.METHODS: The study cohort was composed of all adult (age 18-65 yr) Alberta residents who filled at least 1 an...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Myles Leslie Raad Fadaak Brendan Cord Lethebe Jessie Hart Szostakiwskyj Source Type: research
Assessing the appropriateness of community-based antibiotic prescribing in Alberta, Canada, 2017-2020, using ICD-9-CM codes: a cross-sectional study
CMAJ Open. 2023 Jul 4;11(4):E579-E586. doi: 10.9778/cmajo.20220114. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Antimicrobial resistance is a rising threat to human health, and, with up to 90% of antibiotics prescribed in the community, it is critical to examine Canadian antibiotic stewardship practices in outpatient settings. We carried out a large-scale analysis of appropriateness in community-based prescribing of antibiotics to adults in Alberta, reporting on 3 years of data from physicians practising in the province.METHODS: The study cohort was composed of all adult (age 18-65 yr) Alberta residents who filled at least 1 an...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Myles Leslie Raad Fadaak Brendan Cord Lethebe Jessie Hart Szostakiwskyj Source Type: research
Charting the Next Road Map for CSF Biomarkers in Alzheimer ’s Disease and Related Dementias
AbstractClinical prediction of underlying pathologic substrates in people with Alzheimer ’s disease (AD) dementia or related dementia syndromes (ADRD) has limited accuracy. Etiologic biomarkers — including cerebrospinal fluid (CSF) levels of AD proteins and cerebral amyloid PET imaging — have greatly modernized disease-modifying clinical trials in AD, but their integration into me dical practice has been slow. Beyond core CSF AD biomarkers (including beta-amyloid 1–42, total tau, and tau phosphorylated at threonine 181), novel biomarkers have been interrogated in single- and multi-centered studies with uneven rigor...
Source: Neurotherapeutics - June 28, 2023 Category: Neurology Source Type: research
