Synthesis, Characterization, and Catalytic Application of Colloidal and Supported Mn Nanoparticles
Chemistry. 2024 Feb 28:e202304228. doi: 10.1002/chem.202304228. Online ahead of print.ABSTRACTColloidal and supported manganese nanoparticles were synthesized following an organometallic approach and applied in the catalytic transfer hydrogenation (CTH) of aldehydes and ketones. Reaction parameters for the preparation of colloidal nanoparticles (NPs) were optimized to yield small (2-2.5 nm) and well-dispersed NPs. Manganese NPs were further immobilized on an imidazolium-based supported ionic phase (SILP) and characterized to evaluate NP size, metal loading, and oxidation states. Oxidation of the Mn NPs by the support was o...
Source: Chemistry - February 28, 2024 Category: Chemistry Authors: Johannes Zenner Kelly Tran Liqun Kang Niklas Kinzel Christophe Werl é Serena DeBeer Alexis Bordet Walter Leitner Source Type: research
Mechanism of KAT2A regulation of H3K36ac in manganese-induced oxidative damage to mitochondria in the nervous system and intervention by curcumin
In conclusion, the regulation of mitochondrial oxidative stress by histone acetylation may be an important mechanism of manganese-induced neurotoxicity. This regulation could be achieved by reducing the level of H3K36ac near the promoter region of mitochondrial-associated antioxidant genes via KAT2A. Curcumin mitigates manganese-induced oxidative damage in mitochondria and plays a crucial protective role in manganese-induced oxidative injury in the nervous system.PMID:38417317 | DOI:10.1016/j.ecoenv.2024.116155 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - February 28, 2024 Category: Environmental Health Authors: Yan Liu Jia-Min Zeng Hua Zhao Chun-Yan Ao Li-Hong Ao Jia-Qi Ban Jun Li Source Type: research
Metformin Attenuates Manganese-Induced Oxidative Stress in N27-A Dopaminergic Neuronal Cells
In this study, we investigated the protective effects of metformin against manganese (Mn)-induced cytotoxicity associated with Parkinson's disease-like symptoms in N27-A dopaminergic (DA) cells. Metformin (0.1-1 mM) suppressed Mn (0.4 mM)-induced cell death in a concentration-dependent manner. Metformin pretreatment effectively suppressed the Mn-mediated increase in the levels of oxidative stress markers, such as reactive oxygen species (ROS) and thiobarbituric acid reactive substances. Moreover, metformin restored the levels of the antioxidants, superoxide dismutase, intracellular glutathione, and glutathione peroxidase, ...
Source: Biological and Pharmaceutical Bulletin - February 28, 2024 Category: Drugs & Pharmacology Authors: Jae-Sung Kim Jeong-Yeon Seo Kyeong-Rok Kang HyangI Lim Do Kyung Kim Hong Sung Chun Source Type: research
Metformin Attenuates Manganese-Induced Oxidative Stress in N27-A Dopaminergic Neuronal Cells
In this study, we investigated the protective effects of metformin against manganese (Mn)-induced cytotoxicity associated with Parkinson's disease-like symptoms in N27-A dopaminergic (DA) cells. Metformin (0.1-1 mM) suppressed Mn (0.4 mM)-induced cell death in a concentration-dependent manner. Metformin pretreatment effectively suppressed the Mn-mediated increase in the levels of oxidative stress markers, such as reactive oxygen species (ROS) and thiobarbituric acid reactive substances. Moreover, metformin restored the levels of the antioxidants, superoxide dismutase, intracellular glutathione, and glutathione peroxidase, ...
Source: Biological and Pharmaceutical Bulletin - February 28, 2024 Category: Drugs & Pharmacology Authors: Jae-Sung Kim Jeong-Yeon Seo Kyeong-Rok Kang HyangI Lim Do Kyung Kim Hong Sung Chun Source Type: research
Metformin Attenuates Manganese-Induced Oxidative Stress in N27-A Dopaminergic Neuronal Cells
In this study, we investigated the protective effects of metformin against manganese (Mn)-induced cytotoxicity associated with Parkinson's disease-like symptoms in N27-A dopaminergic (DA) cells. Metformin (0.1-1 mM) suppressed Mn (0.4 mM)-induced cell death in a concentration-dependent manner. Metformin pretreatment effectively suppressed the Mn-mediated increase in the levels of oxidative stress markers, such as reactive oxygen species (ROS) and thiobarbituric acid reactive substances. Moreover, metformin restored the levels of the antioxidants, superoxide dismutase, intracellular glutathione, and glutathione peroxidase, ...
Source: Biological and Pharmaceutical Bulletin - February 28, 2024 Category: Drugs & Pharmacology Authors: Jae-Sung Kim Jeong-Yeon Seo Kyeong-Rok Kang HyangI Lim Do Kyung Kim Hong Sung Chun Source Type: research
A Manganese-based Catalyst System for General Oxidations of Unactivated Olefins, Alkanes, and Alcohols
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Dennis Verspeek, Sebastian Ahrens, Xiaodong Wen, Yong Yang, Yongwang Li, Kathrin Junge, Matthias Beller Non-noble metal-based catalyst systems consisting of inexpensive manganese salts, picolinic acid and various heterocycles enable epoxidation of challenging (terminal) unactivated olefins, selective C-H oxidation of unactivated alkanes, as well as... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - February 27, 2024 Category: Molecular Biology Authors: Dennis Verspeek Source Type: research
Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort
Aging (Albany NY). 2024 Feb 26;16. doi: 10.18632/aging.205602. Online ahead of print.ABSTRACTEpigenetic gestational age acceleration (EGAA) at birth and epigenetic age acceleration (EAA) in childhood may be biomarkers of the intrauterine environment. We investigated the extent to which first-trimester folate, B12, 5 essential, and 7 non-essential metals in maternal circulation are associated with EGAA and EAA in early life. Bohlin EGAA and Horvath pan-tissue and skin and blood EAA were calculated using DNA methylation measured in cord blood (N=351) and mid-childhood blood (N=326; median age = 7.7 years) in the Project Viva...
Source: Aging - February 27, 2024 Category: Biomedical Science Authors: Anne K Bozack Sheryl L Rifas-Shiman Andrea A Baccarelli Robert O Wright Diane R Gold Emily Oken Marie-France Hivert Andres Cardenas Source Type: research
Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort
Aging (Albany NY). 2024 Feb 26;16. doi: 10.18632/aging.205602. Online ahead of print.ABSTRACTEpigenetic gestational age acceleration (EGAA) at birth and epigenetic age acceleration (EAA) in childhood may be biomarkers of the intrauterine environment. We investigated the extent to which first-trimester folate, B12, 5 essential, and 7 non-essential metals in maternal circulation are associated with EGAA and EAA in early life. Bohlin EGAA and Horvath pan-tissue and skin and blood EAA were calculated using DNA methylation measured in cord blood (N=351) and mid-childhood blood (N=326; median age = 7.7 years) in the Project Viva...
Source: Aging - February 27, 2024 Category: Biomedical Science Authors: Anne K Bozack Sheryl L Rifas-Shiman Andrea A Baccarelli Robert O Wright Diane R Gold Emily Oken Marie-France Hivert Andres Cardenas Source Type: research
Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort
Aging (Albany NY). 2024 Feb 26;16. doi: 10.18632/aging.205602. Online ahead of print.ABSTRACTEpigenetic gestational age acceleration (EGAA) at birth and epigenetic age acceleration (EAA) in childhood may be biomarkers of the intrauterine environment. We investigated the extent to which first-trimester folate, B12, 5 essential, and 7 non-essential metals in maternal circulation are associated with EGAA and EAA in early life. Bohlin EGAA and Horvath pan-tissue and skin and blood EAA were calculated using DNA methylation measured in cord blood (N=351) and mid-childhood blood (N=326; median age = 7.7 years) in the Project Viva...
Source: Aging - February 27, 2024 Category: Biomedical Science Authors: Anne K Bozack Sheryl L Rifas-Shiman Andrea A Baccarelli Robert O Wright Diane R Gold Emily Oken Marie-France Hivert Andres Cardenas Source Type: research
Manganese(I)-Catalyzed C –H Allylation of Tryptophans and Their Oligopeptides On Water
Synlett DOI: 10.1055/a-2268-4678 The manganese(I)-catalyzed allylation of the amino acid tryptophan is realized under exceedingly mild conditions using water as a sustainable and non-hazardous reaction medium, instead of classical organic solvents, with great potential for green and sustainable chemistry. Synthetically useful α,β-unsaturated esters can be accessed by reaction with Morita–Baylis–Hillman (MBH) adducts following a fast C–H activation approach. The robustness of this procedure is reflected by kinetic analysis at different reaction temperatures and reduced catalyst loadings are employed. [...] Georg Thi...
Source: Synlett - February 27, 2024 Category: Chemistry Authors: Struwe, Julia Oyama, Tsuyoshi Gallou, Fabrice Ackermann, Lutz Tags: letter Source Type: research
Inhalation exposure to toxic heavy metals in nail salon technicians and health risk assessment using Monte Carlo simulation
CONCLUSION: To effectively reduce pollutant concentration, it is recommended to install a ventilation system near nail salon work tables and conduct continuous monitoring and quality control of nail products.PMID:38407183 | DOI:10.1080/08958378.2024.2315124 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - February 26, 2024 Category: Respiratory Medicine Authors: Zohreh Mohebian Fatemeh Paridokht Sara Karimi Zeverdegani Farzaneh Mohammadi Source Type: research
Internal Vanadium doping and external modification design of P2-type layered Mn-based oxides as competitive cathodes toward Sodium-ion Batteries
In this study, a composite cathode material, Na0.67Ni0.23Mn0.67V0.1O2@Na3V2O2(PO4)2F was developed by surface-coating P2-type Na0.67Ni0.23Mn0.67V0.1O2 with a thin layer of Na3V2O2(PO4)2F to enhance both the electrochemical sodium storage and material air stability. The optimized Na0.67Ni0.23Mn0.67V0.1O2@5wt%Na3V2O2(PO4)2F exhibited a high discharge capacity of 176 mA h g-1 within the 1.5-4.1 V range at a low current density of 17 mA g-1. At an increased current density of 850 mA g-1 within the same voltage window, it still delivered a substantial initial discharge capacity of 112 mAh g-1. These findings validate the signif...
Source: Chemistry - February 26, 2024 Category: Chemistry Authors: Xin Li Xin Lai Qingquan Kong Xuguang An Jing Zhang Xiaolei Li Xiaonan Liu Weitang Yao Source Type: research
Inhalation exposure to toxic heavy metals in nail salon technicians and health risk assessment using Monte Carlo simulation
CONCLUSION: To effectively reduce pollutant concentration, it is recommended to install a ventilation system near nail salon work tables and conduct continuous monitoring and quality control of nail products.PMID:38407183 | DOI:10.1080/08958378.2024.2315124 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - February 26, 2024 Category: Respiratory Medicine Authors: Zohreh Mohebian Fatemeh Paridokht Sara Karimi Zeverdegani Farzaneh Mohammadi Source Type: research
Exposure and Health Risks Posed by Potentially Toxic Elements in Soils of Metal Fabrication Workshops in Mbarara City, Uganda
This study underscores the need to implement regulatory guidelines on the operation and location of MFWs in Uganda. Further research should be undertaken to investigate the emission of the PTEs during welding operations in the MFWs.PMID:38390991 | DOI:10.3390/jox14010011 (Source: Cancer Control)
Source: Cancer Control - February 23, 2024 Category: Cancer & Oncology Authors: Eunice Nuwamanya Denis Byamugisha Caroline K Nakiguli Christopher Angiro Alice V Khanakwa Timothy Omara Simon Ocakacon Patrick Onen Daniel Omoding Boniface Opio Daniel Nimusiima Emmanuel Ntambi Source Type: research
Targeting deoxynivalenol for degradation by a chimeric manganese peroxidase/glutathione system
Ecotoxicol Environ Saf. 2024 Feb 21;273:116130. doi: 10.1016/j.ecoenv.2024.116130. Online ahead of print.ABSTRACTThe manganese peroxidase (MnP) can degrade multiple mycotoxins including deoxynivalenol (DON) efficiently; however, the lignin components abundant in foods and feeds were discovered to interfere with DON catalysis. Herein, using MnP from Ceriporiopsis subvermispora (CsMnP) as a model, it was demonstrated that desired catalysis of DON, but not futile reactions with lignin, in the reaction systems containing feeds could be achieved by engineering MnP and supplementing with a boosting reactant. Specifically, two su...
Source: Ecotoxicology and Environmental Safety - February 23, 2024 Category: Environmental Health Authors: Xiaoyun Su Shuai Wang Xiaolu Wang Wangli Ji Honglian Zhang Tao Tu Nina Hakulinen Huiying Luo None Bin Yao Wei Zhang Huoqing Huang Source Type: research
