Scoliosis Linked to Gene Variant Inhibiting Manganese Utilization
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - January 16, 2019 Category: Orthopaedics Tags: Trends and Innovations Source Type: news
How manganese produces a parkinsonian syndrome
(CNRS) Using X-ray fluorescence at synchrotrons DESY and ESRF, researchers in the Centre d'Etudes Nucl é aires de Bordeaux Gradignan (CNRS/Universit é de Bordeaux) have demonstrated the consequences of a mutation responsible for a hereditary parkinsonian syndrome: accumulated manganese in the cells appears to disturb protein transport. This work, carried out with colleagues at the University of Texas at Austin (USA), was published in ACS Chemical Neuroscience on January 16, 2018. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 16, 2019 Category: Biology Source Type: news
Manganese mobilizes microglial exosomes
(Source: ScienceNOW)
Source: ScienceNOW - January 10, 2019 Category: Science Authors: Williams, E. Tags: twis Source Type: news
Researchers diversify drug development options with new metal catalyst
(University of Illinois at Urbana-Champaign) A University of Illinois team of researchers led by chemistry professor M. Christina White has developed a new manganese-based catalyst that can change the structure of druglike molecules to make new drugs, advancing the pace and efficiency of drug development. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 9, 2019 Category: International Medicine & Public Health Source Type: news
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
In this study, we examined whether Mn2+ activates the multiprotein NLRP3 inflammasome complex to promote neuroinflammation. Exposing activated mouse microglial cells to Mn2+ substantially augmented NLRP3 abundance, caspase-1 cleavage, and maturation of the inflammatory cytokine interleukin-1β (IL-1β). Exposure of mice to Mn2+ had similar effects in brain microglial cells. Furthermore, Mn2+ impaired mitochondrial ATP generation, basal respiratory rate, and spare capacity in microglial cells. These data suggest that Mn-induced mitochondrial defects drove the inflammasome signal amplification. We found that Mn induc...
Source: Signal Transduction Knowledge Environment - January 8, 2019 Category: Science Authors: Sarkar, S., Rokad, D., Malovic, E., Luo, J., Harischandra, D. S., Jin, H., Anantharam, V., Huang, X., Lewis, M., Kanthasamy, A., Kanthasamy, A. G. Tags: STKE Research Articles Source Type: news
Should You Develop Your Own Material Specification and Skip ASTM ’s?
The basic format for an ASTM standardized metal alloy for medical uses includes a specification of the required elements as well as one or more undesirable elements for which there is a maximum allowable amount.
For example, ASTM F2886, last approved in 2017, covers Metal Injection Molded Cobalt-28Chromium-6Molybdenum Components for Surgical Implant Applications. While the name gives part of the recipe, a more-detailed list of elements specifies that chromium must be between 27 and 30%, and molybdenum between 5 and 7%. Thus, these major required alloying elements together constitute 32 to 37% of the mix. Twelve other eleme...
Source: MDDI - November 6, 2018 Category: Medical Devices Authors: William A. Hyman Tags: Regulatory and Compliance Source Type: news
Are Sunflower Seeds Healthy? Here ’s What Experts Say
Certain seeds, like chia and flax, tend to hog the nutritional spotlight. But the less-trendy sunflower seed has plenty of qualities worth highlighting. Here are the health benefits of sunflowers seeds, according to dietitians.
Are sunflower seeds healthy?
Sunflower seeds are rich in nutrients. One serving of shelled sunflower seeds is usually an ounce, which is about 1/4 cup or 4 tablespoons (one to two thumb-sized portions.) They’re particularly high in healthy fat: A serving delivers 14 grams of fat with a mix of monounsaturated and polyunsaturated fats. “The mono- and polyunsaturated fats in sunflower seed...
Source: TIME: Health - October 17, 2018 Category: Consumer Health News Authors: Cassie Shortsleeve Tags: Uncategorized Diet/Nutrition Source Type: news
Scoliosis linked to inability to utilize manganese
A curvature of the spine known as scoliosis has been linked to the body's inability to utilize the essential dietary mineral manganese, according to a study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 9, 2018 Category: Consumer Health News Source Type: news
Scoliosis linked to essential mineral
(Washington University School of Medicine) An inability to properly use the essential mineral manganese could be to blame for some cases of severe scoliosis, according to a new study from Washington University School of Medicine in St. Louis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 9, 2018 Category: International Medicine & Public Health Source Type: news
Manganese plays a key role in bacterial infection
(PLOS) The ability to acquire manganese during infection is essential for the virulence of Enterococcus faecalis in animals, according to a study published Sept. 20, 2018 in the open-access journal PLOS Pathogens by Jos é Lemos of the University of Florida College of Dentistry, and colleagues. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 20, 2018 Category: Biology Source Type: news
Point-of-care sensors to detect manganese from single drop of blood
(University of Illinois at Chicago) A three-year, $1.8 million grant from the National Institutes of Health will enable researchers at the University of Illinois at Chicago to develop portable, easy-to-use sensors that can detect toxic metals in a single drop of blood. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 13, 2018 Category: Biology Source Type: news
Kent State geologist wins grant to study climate change, inspire young scientists
(Kent State University) The National Science Foundation (NSF) presented its prestigious Faculty Early Career Development (CAREER) Award to Dr. Herndon for her project, 'Manganese Biogeochemistry and Impacts on Carbon Storage in Plant-Soil Systems.' The five-year grant is expected to total $487,000. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 13, 2018 Category: Biology Source Type: news
Manganese (Manganese Chloride Injection Solution) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 7, 2018 Category: Drugs & Pharmacology Source Type: news
Medical News Today: What are the benefits of barley water?
Barley is a great source of fiber and contains many other essential minerals, including magnesium, manganese, and selenium. In this article, we look at the benefits of barley water and how to make this nutritious beverage. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 23, 2018 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news
The 6 Best Snacks for Anyone Cutting Out Sugar, According to a Nutritionist
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - February 28, 2018 Category: Consumer Health News Authors: Cynthia Sass, MPH, RD Tags: Uncategorized Food Healthy Eating onetime Source Type: news