New antifungal kills without toxic side effects
The antifungal Amphotericin B (AmB) is an old and effective drug—it saved many COVID-19 patients whose compromised immune systems failed to stop secondary fungal infections. But it sometimes causes life-threatening kidney damage. Now, after more than a decade of sleuthing into this toxicity, researchers have not only found an explanation, but used it and a robotic “chemist” to devise a powerful antifungal alternative without any obvious side effects in mice and human cells. And the strategy that led to the discovery of the compound, described today in
Nature
, may offer a route for detoxifying other antimic...
Source: ScienceNOW - November 8, 2023 Category: Science Source Type: news
South Africa: Over 7 400 Malaria Cases Recorded, 17% Locally Acquired
[SAnews.gov.za] South Africa has recorded over 7 400 malaria cases between January and October this year, with only 17% of these having been locally acquired. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 8, 2023 Category: Infectious Diseases Tags: Health and Medicine Malaria South Africa Southern Africa Source Type: news
Peace Corps agrees to pay $750,000 to family of dead volunteer
A law firm says the Peace Corps has agreed to pay $750,000 to the family of a 24-year-old volunteer from Illinois who died in 2018 in East Africa after the agency’s doctors misdiagnosed a case of malaria (Source: ABC News: Health)
Source: ABC News: Health - November 8, 2023 Category: Consumer Health News Tags: Health Source Type: news
South Africa: Gauteng Health Intensifies Malaria Awareness Campaign
[Govt of SA] Gauteng Health intensifies malaria awareness campaign (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 6, 2023 Category: African Health Tags: Health and Medicine Malaria South Africa Southern Africa Sustainable Development Source Type: news
Africa: WHO Prequalifies First African-Made Combination Therapy for Seasonal Malaria Chemoprevention
[Universal Corporation Ltd] Geneva and Kiambu -- Universal Corporation Ltd (UCL), a Strides Pharma Science Limited (Strides) enterprise, with support from MMV, becomes the first African manufacturer to gain WHO prequalification for their sulfadoxine-pyrimethamine + amodiaquine product. Sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a combination drug used to prevent malaria in children living in areas of seasonal malaria transmission. The combination therapy is employed in seasonal malaria chemoprevention (SMC) programmes and is designed to protect (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 6, 2023 Category: Infectious Diseases Tags: Africa Health and Medicine Malaria Source Type: news
Africa: First African-Manufactured Combination Therapy For Seasonal Malaria Chemoprevention Receives WHO Prequalification
[Universal Corporation Ltd] Geneva and Kiambu -- Universal Corporation Ltd (UCL), a Strides Pharma Science Limited (Strides) enterprise, with support from MMV, becomes the first African manufacturer to gain WHO prequalification for their sulfadoxine-pyrimethamine + amodiaquine product. Sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a combination drug used to prevent malaria in children living in areas of seasonal malaria transmission. The combination therapy is employed in seasonal malaria chemoprevention (SMC) programmes and is designed to protect (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 6, 2023 Category: Infectious Diseases Tags: Africa Health and Medicine Malaria Source Type: news
The fight against malaria
After declining for decades, deaths from the disease are suddenly on the rise. What’s changed? Here's everything you need to know: How many people die from malaria? The mosquito-borne disease currently kills some 620,000 people a year, about 80% of them are children under 5 in sub-Saharan Africa.…#africa #ericochomo #kenya #southasian #djibouti #eastafrican #djibouticity #african #djiboutian #abdulilahahmedabdi (Source: Reuters: Health)
Source: Reuters: Health - November 6, 2023 Category: Consumer Health News Source Type: news
Uganda: Neonatal Conditions Top the List, Malaria Cases Decline in New Health Sector Performance Report
[Nile Post] The annual health sector performance report has unveiled a comprehensive picture of the disease burden affecting the nation, with neonatal conditions emerging as the leading cause of health facility deaths across all age groups, accounting for a substantial 10.3%. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 6, 2023 Category: Infectious Diseases Tags: East Africa Health and Medicine Malaria Uganda Source Type: news
Certain Scientists, Journals Pose'Potential Threats To Vaccine Confidence': CDC
Certain Scientists, Journals Pose 'Potential Threats To Vaccine Confidence': CDC Authored by Zachary Stieber via The Epoch Times (emphasis ours), Scientists and journals that conduct and publish certain research pose a problem for the federal government's vaccination campaigns that should be…#cdc #zacharystieber #epochtimes #atlanta #colinbernatzky #vladimiruversky #florida #modernacovid19 #malaria #pertussis (Source: Reuters: Health)
Source: Reuters: Health - November 4, 2023 Category: Consumer Health News Source Type: news
South Africa: Malaria Season - Travellers Warned to Take Precautions
[SAnews.gov.za] The National Institute for Communicable Diseases (NICD) is urging people travelling to malaria-endemic areas to take the appropriate precautions this summer. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 3, 2023 Category: Infectious Diseases Tags: Health and Medicine Malaria South Africa Southern Africa Travel and Tourism Source Type: news
Africa: Bill Gates Talks Gene Drives, mRNA, and U.S.$40m in Science Funding
[allAfrica] Dakar -- Infectious diseases continue to be the major causes of deaths in Africa. The burden of existing, emerging and re-emerging diseases like malaria, tuberculosis, HIV/AIDS, cholera, schistosomiasis, lymphatic filariasis, sleeping sickness, Ebola and SARS continues to grow - and once you move beyond mortality statistics, the huge s ocio-economic costs - care and treatment, hospital admissions, productivity loss, and disability reveals a heavy toll on the continent. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 31, 2023 Category: African Health Tags: Africa External Relations Health and Medicine International Organizations and Africa Source Type: news
Tanzania: Maternal Deaths Drops
[Daily News] PRESIDENT Dr Samia Suluhu Hassan yesterday launched the new Tanzania Demographic and Health Survey and Malaria Indicator Survey (2022 TDHS-MIS), which shows that the country has cut down maternal mortality rate by 80 per cent. (Source: AllAfrica News: Pregnancy and Childbirth)
Source: AllAfrica News: Pregnancy and Childbirth - October 30, 2023 Category: OBGYN Tags: East Africa Health and Medicine Pregnancy and Childbirth Tanzania Source Type: news
Malaria Is Spreading In The U.S. An Infectious Disease Doctor Explains This Troubling Trend
A patient developed malaria in Arkansas earlier in October, making now 10 cases this year that occurred in Florida, Texas, Maryland and Arkansas. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - October 27, 2023 Category: Pharmaceuticals Authors: Mark Kortepeter, Contributor Tags: Healthcare /healthcare Innovation /innovation Editors' Pick editors-pick standard Source Type: news
This new malaria vaccine will transform our battle with the deadliest creatures on Earth | Devi Sridhar
The breakthrough has come just in time: malaria has re-emerged in my home state of Florida, and will spread further thanks to climate changeWant to guess the most dangerous animal in the world? When my team asked children in Edinburgh during a public outreach event with schools, they said sharks, alligators, spiders and lions. All good guesses, but none on target. The deadliest animal is the mighty mosquito, which kills more than1 million people a year. Almost 700 million people contract a mosquito-borne illness each year. Mosquitoes carry serious diseases like malaria, dengue fever, West Nile virus, Zika virus and chikung...
Source: Guardian Unlimited Science - October 26, 2023 Category: Science Authors: Devi Sridhar Tags: Malaria Health World news Africa Science Source Type: news
First malaria vaccine slashes early childhood deaths
In a major analysis in Africa, the first vaccine approved to fight malaria cut deaths among young children by 13% over nearly 4 years, the World Health Organization (WHO) reported last week. The huge evaluation of a pilot rollout of the vaccine, called RTS,S or Mosquirix and made by GlaxoSmithKline, also showed a 22% reduction in severe malaria in kids young enough to receive a three-shot series. Hundreds of thousands of children are born annually in the parts of Ghana, Kenya, and Malawi included in the analysis, for which WHO revealed the final data on 20 October at the annual meeting of the American Society of Tropical M...
Source: ScienceNOW - October 24, 2023 Category: Science Source Type: news
