The effect of magnesium chloride as an anti-icing agent on tire/road friction coefficient - Leggett TS, Brewer E.
This article reports on the findings of tests designed to measure the effectiveness of magnesium chloride (MgCL ₂) as an anti-icing agent on tire/road friction coefficient. Skid tests under various conditions are conducted using a 1996 Chevrolet Caprice a... (Source: SafetyLit)
Source: SafetyLit - February 18, 2020 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Dry reforming of methane by stable Ni-Mo nanocatalysts on single-crystalline MgO
Large-scale carbon fixation requires high-volume chemicals production from carbon dioxide. Dry reforming of methane could provide an economically feasible route if coke- and sintering-resistant catalysts were developed. Here, we report a molybdenum-doped nickel nanocatalyst that is stabilized at the edges of a single-crystalline magnesium oxide (MgO) support and show quantitative production of synthesis gas from dry reforming of methane. The catalyst runs more than 850 hours of continuous operation under 60 liters per unit mass of catalyst per hour reactive gas flow with no detectable coking. Synchrotron studies also show ...
Source: ScienceNOW - February 12, 2020 Category: Science Authors: Song, Y., Ozdemir, E., Ramesh, S., Adishev, A., Subramanian, S., Harale, A., Albuali, M., Fadhel, B. A., Jamal, A., Moon, D., Choi, S. H., Yavuz, C. T. Tags: Chemistry, Materials Science reports Source Type: news
Structural basis of second-generation HIV integrase inhibitor action and viral resistance
Although second-generation HIV integrase strand-transfer inhibitors (INSTIs) are prescribed throughout the world, the mechanistic basis for the superiority of these drugs is poorly understood. We used single-particle cryo–electron microscopy to visualize the mode of action of the advanced INSTIs dolutegravir and bictegravir at near-atomic resolution. Glutamine-148->histidine (Q148H) and glycine-140->serine (G140S) amino acid substitutions in integrase that result in clinical INSTI failure perturb optimal magnesium ion coordination in the enzyme active site. The expanded chemical scaffolds of second-generation c...
Source: ScienceNOW - February 12, 2020 Category: Science Authors: Cook, N. J., Li, W., Berta, D., Badaoui, M., Ballandras-Colas, A., Nans, A., Kotecha, A., Rosta, E., Engelman, A. N., Cherepanov, P. Tags: Biochemistry, Microbiology reports Source Type: news
Janssen to Highlight Depth of Solid Tumor Portfolio at ASCO GU
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet needs continue...
Source: Johnson and Johnson - February 3, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
Magnesium Disorders Up Hypocalcemia Risk After Thyroidectomy Magnesium Disorders Up Hypocalcemia Risk After Thyroidectomy
Hypocalcemia occurred in nearly 20% of patients following thyroidectomy in the large study, however, most cases resolved at 1 year.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - January 17, 2020 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
Magnesium Inversely Linked to Risk for Coronary Heart Disease
FRIDAY, Dec. 27, 2019 -- For postmenopausal women, dietary magnesium is inversely associated with fatal coronary heart disease (CHD), according to a study published online Dec. 12 in the Journal of Women ' s Health.
Jason Li, D.O., from the Alpert... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 27, 2019 Category: Pharmaceuticals Source Type: news
Could higher magnesium intake reduce fatal coronary heart disease risk in women?
(Mary Ann Liebert, Inc./Genetic Engineering News) A new prospective study based on data from the Women's Health Initiative found a potential inverse association between dietary magnesium and fatal coronary heart disease in postmenopausal women. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 23, 2019 Category: International Medicine & Public Health Source Type: news
Magnetic measurements on micrometer-sized samples under high pressure using designed NV centers
We report a method for spatially resolved optical magnetometry based on imaging a layer of nitrogen-vacancy (NV) centers created at the surface of a diamond anvil. We illustrate the method using two sets of measurements realized at room temperature and low temperature, respectively: the pressure evolution of the magnetization of an iron bead up to 30 gigapascals showing the iron ferromagnetic collapse and the detection of the superconducting transition of magnesium dibromide at 7 gigapascals. (Source: ScienceNOW)
Source: ScienceNOW - December 11, 2019 Category: Science Authors: Lesik, M., Plisson, T., Toraille, L., Renaud, J., Occelli, F., Schmidt, M., Salord, O., Delobbe, A., Debuisschert, T., Rondin, L., Loubeyre, P., Roch, J.-F. Tags: Physics reports Source Type: news
Zydus Cadila files NDA for Saroglitazar Magnesium
NASH is a progressive disease of the liver and a significant unmet medical need. There are currently no treatments available for the treatment of NASH. aroglitazar Mg has previously demonstrated improvement in both liver enzymes along with favorable effects on lipid and glycemic indices in patients with nonalcoholic fatty liver disease in Phase II clinical trials. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 4, 2019 Category: Pharmaceuticals Source Type: news
Magnesium for Salmonella growth
(Source: ScienceNOW)
Source: ScienceNOW - November 20, 2019 Category: Science Authors: Ash, C. Tags: Immunology, Microbiology twis Source Type: news
Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation
The pleiotropic host resistance factor SLC11A1 (NRAMP1) defends against diverse intracellular pathogens in mammals by yet-unknown mechanisms. We compared Salmonella infection of coisogenic mice with different SLC11A1 alleles. SLC11A1 reduced Salmonella replication and triggered up-regulation of uptake systems for divalent metal cations but no other stress responses. SLC11A1 modestly diminished iron availability and acutely restricted Salmonella access to magnesium. Growth of Salmonella cells in the presence of SLC11A1 was highly heterogeneous and inversely correlated with expression of the crucial magnesium transporter gen...
Source: ScienceNOW - November 20, 2019 Category: Science Authors: Cunrath, O., Bumann, D. Tags: Immunology, Microbiology reports Source Type: news
Magnesium Isoglycyrrhizinate Injection in Acute DILI Magnesium Isoglycyrrhizinate Injection in Acute DILI
A newly developed agent, magnesium isoglycyrrhizinate, shows promise as an effective and safe treatment for patients with acute drug-induced liver injury.Liver International (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - November 20, 2019 Category: Surgery Tags: Gastroenterology Journal Article Source Type: news
Talicia (Omeprazole Magnesium, Amoxicillin and Rifabutin Delayed-release Capsules) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 13, 2019 Category: Drugs & Pharmacology Source Type: news
Vitamin D deficiency symptoms: Noticing this change in your hair could be a warning sign
VITAMIN D is a group of fat-soluble vitamins responsible for increasing intestinal absorption of calcium, magnesium and phosphate. It is a vitamin that is essential for good health and noticing a certain change in your hair could mean you are lacking the ‘sunshine vitamin’. What is it? (Source: Daily Express - Health)
Source: Daily Express - Health - November 11, 2019 Category: Consumer Health News Source Type: news
FDA Approves Talicia (omeprazole magnesium, amoxicillin and rifabutin) for the Treatment of H. pylori Infection in Adults
TEL-AVIV, Israel and RALEIGH, N.C., Nov. 04, 2019 (GLOBE NEWSWIRE) -- RedHill Biopharma Ltd. (Nasdaq: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the“Company”), a specialty biopharmaceutical company primarily focused... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - November 4, 2019 Category: Drugs & Pharmacology Source Type: news
