FDA Approves Xywav (calcium, magnesium, potassium, and sodium oxybates) Oral Solution for Cataplexy or Excessive Daytime Sleepiness Associated with Narcolepsy
DUBLIN, July 22, 2020 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the U.S. Food and Drug Administration (FDA) approved Xywav™ (calcium, magnesium, potassium, and sodium oxybates)... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 22, 2020 Category: Drugs & Pharmacology Source Type: news
A dual antenatal therapy benefits extreme preterm babies better than either alone or none
(University of Alabama at Birmingham) Researchers, led by Samuel Gentle, MD, assistant professor of pediatrics in the University of Alabama at Birmingham School of Medicine, report that antenatal treatment with both magnesium sulfate and corticosteroids together yields an increased benefit for children born at 22 to 26 weeks of gestation, compared to no antenatal treatment or with either therapy alone. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2020 Category: International Medicine & Public Health Source Type: news
Day in, day out: Targeting the daily magnesium " rhythm " can optimize crop yield
(Okayama University) Many processes of photosynthesis, including the intake of magnesium, follow a pattern of variation over 24 hours. In a new study, scientists from Okayama University, Japan and Fujian A& F University, China, tested the effect of this variation on the efficiency of photosynthesis in rice plants. Their findings suggest potential candidates for modification for increasing the yield of rice crops, thereby offering a potential solution to the global food shortage. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 10, 2020 Category: Biology Source Type: news
Best supplements for the heart - the 3p a day capsules to lower your risk of heart attacks
SUPPLEMENTS could be used to improve the health of your heart, as well as to protect against heart attack symptoms and signs. Add these cheap magnesium capsules to your diet to lower your risk of high blood pressure. (Source: Daily Express - Health)
Source: Daily Express - Health - June 25, 2020 Category: Consumer Health News Source Type: news
Aluminum oxide crystal tested as a UV radiation sensor
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Doped with carbon and magnesium, the material becomes thermoluminescent in response to UV radiation. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2020 Category: Cancer & Oncology Source Type: news
U.S. FDA Approves New Pediatric Formulation of SIRTURO ® (bedaquiline) as Part of Combination Therapy to Treat Children with Pulmonary Multidrug-Resistant Tuberculosis
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO®
(bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelerated appro...
Source: Johnson and Johnson - May 27, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
Ronald Reagan ’s Secret Cancer Cure
There’s no faster way to purify your body of viruses, bacteria and fungi — and at the same time ramp up your immune system — than a 125-year-old “cure” banned by the FDA.
I’m talking about ozone therapy — and it’s not just good for cleansing your body.
You see, ozone — a special “energized” kind of oxygen — can help heal almost any condition.
Despite being banned by the FDA back in the 1940s, after more than 60 years of successful use, ozone therapy has saved millions of lives in countries where it has become a commonplace medical treatment.
In countries like Germany, I...
Source: Al Sears, MD Natural Remedies - May 12, 2020 Category: Complementary Medicine Authors: Dr.A.Sears Tags: Health Source Type: news
Best supplements for the heart - the best capsule to protect against high blood pressure
SUPPLEMENTS could be used to improve the health of your heart, as well as to protect against high blood pressure symptoms and signs. Add these cheap magnesium capsules to your diet to lower your risk of heart attacks. (Source: Daily Express - Health)
Source: Daily Express - Health - April 19, 2020 Category: Consumer Health News Source Type: news
Best supplements for tiredness - the 3p a day capsules to prevent fatigue and boost energy
SUPPLEMENTS could be used to prevent tiredness and fatigue symptoms. Add these cheap capsules to your diet to avoid feeling sleepy or drowsy during the day, while also boosting your overall energy. Do you eat enough magnesium-rich foods? (Source: Daily Express - Health)
Source: Daily Express - Health - April 14, 2020 Category: Consumer Health News Source Type: news
Bupivacaine With/Without Magnesium Sulfate for Postop Analgesia Bupivacaine With/Without Magnesium Sulfate for Postop Analgesia
Does the addition of magnesium sulfate as an adjuvant of epidural bupivacaine improve postoperative analgesia over bupivacaine alone?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 13, 2020 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news
What Causes Tachycardia?
Discussion
Tachycardia is a rapid heart rate that is above normal for age and level of exertion. Tachycardia is common, particularly sinus tachycardia due to normally encountered circumstances such as pain, fever or exercise. It is usually a normal physiologic process but sustained tachycardia often indicates a potentially abnormal underlying cause.
Sinus tachycardia has a rapid heart rate with normal P waves and P-R intervals and variations from moment to moment and respiration. Generally it is not over 200 beats/minute. Vagal stimulation can slow the heart rate; this is a gradual slowing, not an abrupt slowing seen in ...
Source: PediatricEducation.org - March 23, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis
Hypomagnesemia is a significant risk factor for critically ill patients to develop sepsis, a life-threatening disease with a mortality rate over 25%. Our clinic data analysis showed that hypomagnesemia is associated with a decreased monocyte count in septic patients. At the cellular level, we found that Mg2+ inhibits pyroptosis. Specifically, Mg2+ limits the oligomerization and membrane localization of gasdermin D N-terminal (GSDMD-NT) upon the activation of either the canonical or noncanonical pyroptotic pathway. Mechanistically, we demonstrated that Ca2+ influx is a prerequisite for the function of GSDMD-NT. Mg2+ blocks ...
Source: Current Awareness Service for Health (CASH) - March 13, 2020 Category: Consumer Health News Source Type: news
New research finds infant cereal consumption is associated with improved nutrient intake
(Pollock Communications) An investigation of infant feeding patterns found infants and toddlers consuming baby cereal, such as rice cereal, had higher intakes of key nutrients of concern, such as calcium, magnesium, iron, zinc and vitamin E. The study illustrates the importance of rice baby cereal in the diets of infants and toddlers in achieving proper nutrition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 10, 2020 Category: International Medicine & Public Health Source Type: news
What Are Some Risk Factors for Cerebral Palsy?
Discussion
The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
Mycobacterium tuberculosis has an unusual outer membrane that lacks canonical porin proteins for the transport of small solutes to the periplasm. We discovered that 3,3-bis-di(methylsulfonyl)propionamide (3bMP1) inhibits the growth of M. tuberculosis, and resistance to this compound is conferred by mutation within a member of the proline-proline-glutamate (PPE) family, PPE51. Deletion of PPE51 rendered M. tuberculosis cells unable to replicate on propionamide, glucose, or glycerol. Growth was restored upon loss of the mycobacterial cell wall component phthiocerol dimycocerosate. Mutants in other proline-glutamate (PE)/PPE ...
Source: ScienceNOW - March 4, 2020 Category: Science Authors: Wang, Q., Boshoff, H. I. M., Harrison, J. R., Ray, P. C., Green, S. R., Wyatt, P. G., Barry, C. E. Tags: Medicine, Diseases reports Source Type: news
