Madagascar Health Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Heterogeneity in elimination efforts could increase the risk of resurgence of lymphatic filariasis in Madagascar
CONCLUSION: Gaps in the implementation of LF elimination programme can increase the risk of resurgence and undermine elimination efforts. In Madagascar, districts that have not attained elimination pose a significant risk for those that have achieved it. More research is needed to help guide LF elimination programme on the optimal strategies for surveillance and control that maximize the chances to sustain elimination and avoid resurgence.PMID:38548211 | DOI:10.1016/j.meegid.2024.105589 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - March 28, 2024 Category: Genetics & Stem Cells Authors: Elinambinina Rajaonarifara Benjamin Roche Cedric B Chesnais Holivololona Rabenantoandro Michelle Evans Andres Garchitorena Source Type: research

Genes, Vol. 15, Pages 429: Cytogenetic Analysis of Satellitome of Madagascar Leaf-Tailed Geckos
Rovatsos Satellite DNA (satDNA) consists of sequences of DNA that form tandem repetitions across the genome, and it is notorious for its diversity and fast evolutionary rate. Despite its importance, satDNA has been only sporadically studied in reptile lineages. Here, we sequenced genomic DNA and PCR-amplified microdissected W chromosomes on the Illumina platform in order to characterize the monomers of satDNA from the Henkel&rsquo;s leaf-tailed gecko U. henkeli and to compare their topology by in situ hybridization in the karyotypes of the closely related G&uuml;nther&rsquo;s flat-tail gecko U....
Source: Genes - March 28, 2024 Category: Genetics & Stem Cells Authors: Alona Yurchenko Tom áš Pšenička Pablo Mora Juan Alberto Marchal Ortega Antonio S ánchez Baca Michail Rovatsos Tags: Article Source Type: research

Can cyclone exposure explain behavioural and demographic variation among lemur species?
In this study, we created a detailed cyclone impact map for Madagascar using Koppen-Geiger climate class, historical cyclone tracks, the Saffir Class of cyclone and hurricane intensity, and precipitation data. We also used existing literature to calculate a resilience score f or 26 lemur species for which data existed on resilience traits. Our cyclone impact map was then overlaid on known geographic ranges of these species and compared to resilience score while controlling for phylogenetic non-independence and spatial autocorrelation. We found no association between cycl one impact in a lemur range and their resilience sco...
Source: PLoS One - March 27, 2024 Category: Biomedical Science Authors: Alison M. Behie Source Type: research

Implementation of an antibiotic resistance surveillance tool in Madagascar, the TSARA project: a prospective, observational, multicentre, hospital-based study protocol
Introduction Antimicrobial resistance (AMR) has become a significant public health threat. Without any interventions, it has been modelled that AMR will account for an estimated 10 million deaths annually by 2050, this mainly affects low/middle-income countries. AMR has a systemic negative perspective affecting the overall healthcare system down to the patient’s personal outcome. In response to this issue, the WHO urged countries to provide antimicrobial stewardship programmes (ASPs). ASPs in hospitals are a vital component of national action plans for AMR, and have been shown to significantly reduce AMR, in particul...
Source: BMJ Open - March 19, 2024 Category: General Medicine Authors: Elias, C., Raad, M., Rasoanandrasana, S., Raherinandrasana, A. H., Andriananja, V., Raberahona, M., Moore, C. E., Randria, M., Raskine, L., Vanhems, P., Babin, F.-X. Tags: Open access, Infectious diseases Source Type: research

Evaluation of a novel approach to community health care delivery in Ifanadiana District, Madagascar
PLOS Glob Public Health. 2024 Mar 12;4(3):e0002888. doi: 10.1371/journal.pgph.0002888. eCollection 2024.ABSTRACTDespite widespread adoption of community health (CH) systems, there are evidence gaps to support global best practice in remote settings where access to health care is limited and community health workers (CHWs) may be the only available providers. The nongovernmental health organization Pivot partnered with the Ministry of Public Health (MoPH) to pilot a new enhanced community health (ECH) model in rural Madagascar, where one CHW provided care at a stationary CH site while additional CHWs provided care via proac...
Source: Rural Remote Health - March 12, 2024 Category: Rural Health Authors: B énédicte Razafinjato Luc Rakotonirina Laura F Cordier Anna Rasoarivao Mamy Andrianomenjanahary Lanto Marovavy Feno Hanitriniaina Isa ïe Jules Andriamiandra Alishya Mayfield Daniel Palazuelos Giovanna Cowley Andriamanolohaja Ramarson Felana Ihantamala Source Type: research

A new orchid species expands Darwin's predicted pollination guild in Madagascar
Curr Biol. 2024 Mar 11;34(5):R189-R190. doi: 10.1016/j.cub.2024.01.012.ABSTRACTThe world-renowned pollination system of the long-spurred orchid Angraecum sesquipedale Thouars and the long-tongued hawkmoth Xanthopan praedicta (Rothschild & Jordan, 1903), from Madagascar, is the best-known example of the predictive power of evolutionary ecology1,2, yet its actual degree of specialisation remains poorly described due to the incompleteness of the pollination record of X. praedicta. Here, we describe another species from Madagascar, an angraecoid orchid distantly related to the genus Angraecum Bory, that has evolved these e...
Source: Current Biology - March 12, 2024 Category: Biology Authors: Jo ão Farminhão Marie Savignac Vincent Droissart Porter P Lowry Nirina Rajaonarivelo Brigitte Ramandimbisoa Simon Verlynde Arsela Todivelo Tariq St évart Source Type: research

Spatial heterogeneity of neo- and paleo-endemism for plants in Madagascar
Curr Biol. 2024 Mar 5:S0960-9822(24)00165-9. doi: 10.1016/j.cub.2024.02.023. Online ahead of print.ABSTRACTMadagascar is a biogeographically unique island with a remarkably high level of endemism. However, endemic taxa in Madagascar are massively threatened due to unprecedented pressures from anthropogenic habitat modification and climate change. A comprehensive phylogeny-based biodiversity evaluation of the island remains lacking. Here, we identify hotspots of taxonomic and phylogenetic plant diversity and neo- and paleo-endemism by generating a novel dated tree of life for the island. The tree is based on unprecedented s...
Source: Current Biology - March 9, 2024 Category: Biology Authors: Wyckliffe Omondi Omollo Romer Narindra Rabarijaona Rindra Manasoa Ranaivoson Mijoro Rakotoarinivo Russell L Barrett Qiang Zhang Yang-Jun Lai Jian-Fei Ye Chi Toan Le Alexandre Antonelli Zhi-Duan Chen Bing Liu Li-Min Lu Source Type: research

Socio-ecological risk factors associated with human flea infestations of rural household in plague-endemic areas of Madagascar
by Ad élaïde Miarinjara, Annick Onimalala Raveloson, Stephen Gilbert Mugel, Nick An, Andry Andriamiadanarivo, Minoarisoa Esther Rajerison, Rindra Vatosoa Randremanana, Romain Girod, Thomas Robert Gillespie Plague is a flea-borne fatal disease caused by the bacteriumYersinia pestis, which persists in rural Madagascar. Although fleas parasitizing rats are considered the primary vectors ofY.pestis, the human flea,Pulex irritans, is abundant in human habitations in Madagascar, and has been found naturally infected by the plague bacterium during outbreaks. WhileP.irritans may therefore play a role in plague transmission if p...
Source: PLoS Neglected Tropical Diseases - March 7, 2024 Category: Tropical Medicine Authors: Ad élaïde Miarinjara Source Type: research

Rift Valley Fever
Rift Valley fever (RVF) is a zoonotic viral disease that affects domestic and wild ruminants such as cattle, sheep, goats, camels, and buffaloes. Rift valley fever virus (RVFV), the causative agent of RVF, can also infect humans. RVFV is an arthropod-borne virus (arbovirus) that is primarily spread through the bites of infected mosquitoes or exposure to infected blood. RVFV was first isolated and characterized in the Rift Valley of Kenya in 1931 and is endemic throughout sub-Saharan Africa, including Comoros and Madagascar, the Arabian Peninsula (Saudi Arabia and Yemen), and Mayotte. (Source: Veterinary Clinics of North Am...
Source: Veterinary Clinics of North America: Food Animal Practice - March 6, 2024 Category: Veterinary Research Authors: J. Brian Kimble, Leela Noronha, Jessie D. Trujillo, Dana Mitzel, Juergen A. Richt, William C. Wilson Source Type: research

Characteristics of Hospitalized COVID-19 Patients at Admission and Factors Associated with Clinical Severity in Low- and Middle-Income Countries: An Observational Study
The objective of this observational, prospective, hospital-based multicentric study was to describe clinical features and outcomes of laboratory-confirmed COVID-19 patients hospitalized in each of the participating centers in Bangladesh, Guinea, Ivory Coast, Lebanon, Madagascar, and Mali during the first year of the pandemic (March 5, 2020 to May 4, 2021). The study outcome was the clinical severity of COVID-19, defined as hospitalization in intensive care unit or death. Multivariate logistic regression models were performed to identify independent variables associated with disease severity. Overall, 1,096 patients were in...
Source: The American Journal of Tropical Medicine and Hygiene - February 27, 2024 Category: Tropical Medicine Authors: Marianne Abifadel Kaousar Ahmmed Sayera Banu Ibrahima Camara Fahmida Chowdhury Daouda Coulibaly Georges Dabar C édric Dananché Rachel Daw Zakiul Hassan Magali Herv é Ariful Islam Florence Komurian-Pradel Jean-Pierre Kouam é Bourema Kouriba Josette Naj Source Type: research