NH Man Says Sister’s Rare Brain Disease Changed His Life
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 5, 2013 Category: Consumer Health News Authors: Kckatzman Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Brain Disease Bree Sison Catholic Medical Center CBS Boston Robert Blodgett Shirley Cummings Source Type: news

Patients May Have Been Exposed To Rare Brain Disease In NH
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 5, 2013 Category: Consumer Health News Authors: Kckatzman Tags: Health Local News Seen On WBZ-TV Watch Listen Brain Disease CBS Boston Creutzfeldt-Jakob Disease Michael Rosenfield NH Health Department Source Type: news

New Hampshire fears eight exposed to rare brain disease in hospital
BOSTON (Reuters) - New Hampshire warned on Wednesday that eight patients who recently underwent neurosurgery at a Manchester hospital may have been exposed to a rare brain condition similar to "mad cow" disease in cattle. (Source: Reuters: Health)
Source: Reuters: Health - September 4, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

8 N.H. patients told surgical equipment may have exposed them to brain disease
Officials are "95 percent sure" that patient had brain surgery in New Hampshire in May before dying in August of Creutzfeldt-Jakob Disease (CJD) (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - September 4, 2013 Category: Consumer Health News Source Type: news

Man Dies Of Rare Case Of Degenerative Brain Disease In NH
CONCORD, N.H. (CBS/AP) — The New Hampshire Department of Health and Human Services says a person has died from a rare, degenerative brain disease in the state and it’s possible other patients may be infected. A news conference explaining the case of sporadic Creutzfeldt-Jakob Disease Wednesday said the person died at Catholic Medical Center in Manchester. Authorities say the victim had brain surgery there in May. The man was later readmitted to the hospital with signs of rapidly advancing dementia. Health officials say most reported cases of Creutzfeldt-Jakob disease happen spontaneously, when an agent causes prote...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 4, 2013 Category: Consumer Health News Authors: Kckatzman Tags: Health Local News Seen On WBZ-TV Watch Listen Brain Disease CBS Boston Creutzfeldt-Jakob Disease Michael Rosenfield NH Health Department Source Type: news

NH Investigating Rare Case Of Degenerative Brain Disease
CONCORD, N.H. (AP) — The New Hampshire Department of Health and Human Services says it’s investigating one case of a rare, degenerative brain disease in the state. A news conference explaining the case of sporadic Creutzfeldt-Jakob Disease has been scheduled for 3 p.m. Wednesday at Catholic Medical Center in Manchester. Officials from the Manchester Public Health Department also will be present. Health officials say most reported cases of Creutzfeldt-Jakob disease happen spontaneously, when an agent causes proteins in the brain to fold incorrectly. Some cases involve a genetic mutation that is passed down among fam...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 4, 2013 Category: Consumer Health News Authors: Kckatzman Tags: Health Local News Brain Disease CBS Boston Creutzfeldt-Jakob Disease mad cow disease NH Health Department WBZ Source Type: news

Vegetarian diagnosed with human equivalent of Mad Cow Disease
Man may have just weeks to live after being diagnosed with human equivalent of Mad Cow Disease despite being vegetarian for the last five years.     (Source: Telegraph Health)
Source: Telegraph Health - August 23, 2013 Category: Consumer Health News Source Type: news

Vegetarian, 28, given just months to live after being diagnosed with Mad Cow Disease he may have caught before he stopped eating meat five years ago
Ritchii Kara, from Brighton, was diagnosed with Creutzfeldt-Jakob Disease last August and was given just 14 months to live. (Source: the Mail online | Health)
Source: the Mail online | Health - August 23, 2013 Category: Consumer Health News Source Type: news

The study of deadly human prion diseases improved by new models
By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of these unusual but deadly diseases... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 21, 2013 Category: Consumer Health News Tags: CJD / vCJD / Mad Cow Disease Source Type: news

New models advance the study of deadly human prion diseases
(Whitehead Institute for Biomedical Research) By directly altering the gene coding for the prion protein, Whitehead Institute researchers have created mouse models of two neurodegenerative prion diseases, each of which manifests in different regions of the brain. These new models for fatal familial insomnia and Creutzfeldt-Jakob disease accurately reflect the distinct patterns of destruction caused by the these diseases in humans. Remarkably, as different as each disease is, they both spontaneously generate infectious prions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 19, 2013 Category: Global & Universal Source Type: news

The flexible tail of the prion protein poisons brain cells
Prion proteins are the infectious pathogens that cause Mad Cow Disease and Creutzfeldt-Jakob disease. They occur when a normal prion protein becomes deformed and clumped. The naturally occurring prion protein is harmless and can be found in most organisms. In humans, it is found in our brain cell membrane. By contrast, the abnormally deformed prion protein is poisonous for the brain cells. Adriano Aguzzi, Professor of Neuropathology at the University of Zurich and University Hospital Zurich, has spent many years exploring why this deformation is poisonous... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 3, 2013 Category: Consumer Health News Tags: CJD / vCJD / Mad Cow Disease Source Type: news

3-D look at prion may help find cure to brain diseases, University of Alberta work shows
The work of University of Alberta researchers and their teams has contributed to an important next step in finding a cure for deadly prion-folding diseases in humans and animals. Professor Michael James of the University of Alberta Department of Biochemistry, Professor Nat Kav of the Department of Agricultural, Food and Nutritional Science and their labs collaborated to produce mini-antibodies and antibody fragments used by the Institute of Neuropathology in Zurich to study interactions between the antibodies and the prion protein and how it results in cell death... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 2, 2013 Category: Consumer Health News Tags: CJD / vCJD / Mad Cow Disease Source Type: news

How antiprion antibodies cause neurodegeneration
It has been suggested that antibodies against prion protein might have therapeutic value. However, a study in this week's Nature shows that many antiprion antibodies cause neurotoxicity and also reveals the mechanism underlying these observations. The prion protein - which in a misfolded form is associated with neurotoxic effects such as those seen in Creutzfeldt-Jakob disease - contains a globular domain and a flexible tail. Aguzzi and colleagues show that antibodies against the globular domain cause neurotoxicity in mice and cerebellar cultured slices... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 31, 2013 Category: Consumer Health News Tags: CJD / vCJD / Mad Cow Disease Source Type: news

Important step toward pharmacologic development of treatment for prion diseases
A team of researchers from Case Western Reserve University School of Medicine have identified a mechanism that can prevent the normal prion protein from changing its molecular shape into the abnormal form responsible for neurodegenerative diseases. This finding, published in the journal Cell Reports, offers new hope in the battle against a foe that until now has always proved fatal. Prion diseases include Creuzfeldt-Jakob disease and fatal familial insomnia. Unlike other transmissible diseases, the infectious agent is not a virus or bacteria, but an abnormally shaped prion protein... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 23, 2013 Category: Consumer Health News Tags: CJD / vCJD / Mad Cow Disease Source Type: news

Up to 20 patients 'at risk of CJD'
Up to 20 people who had surgery at an Irish hospital could be at risk of Creutzfeldt-Jakob Disease after one patient was diagnosed with the brain-wasting condition. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 19, 2013 Category: Consumer Health News Source Type: news