The impact of Libman-sacks endocarditis on inpatient outcomes with systemic lupus erythematosus: A retrospective study
This study aimed to explore the characteristics and prognosis of SLE patients with LSE and the impact of LSE in patients with SLE on inpatient outcomes including inpatient mortality, length of stay, acute heart failure, atrial fibrillation, and cerebrovascular accidents (CVA).METHODS: This study included adult patients who were hospitalized with SLE between the years 2019 and 2020, using the National Inpatient Sample (NIS) database. The total number of patients with a diagnosis of SLE in the years 2019 and 2020 in the NIS database was 150,411. Of those, 349 had a diagnosis of LSE. The study population was divided into two ...
Source: Lupus - April 2, 2024 Category: Rheumatology Authors: Halah Alfatlawi Abdulmajeed Alharbi Momin Shah Yusuf Nawras Nezam Altorok Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Combined rituximab and belimumab to treat recalcitrant epidermolysis bullosa aquisita associated with systemic lupus erythematosus
Br J Dermatol. 2024 Apr 2:ljae141. doi: 10.1093/bjd/ljae141. Online ahead of print.NO ABSTRACTPMID:38561894 | DOI:10.1093/bjd/ljae141 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 2, 2024 Category: Dermatology Authors: Thomas J Tull Emma C Benton Kristina Semkova Natalie A Watson John B Mee Begona Lopez Jane Setterfield Barbara Carey Sajjad Ajmad Scott J Robbie Richard W Groves Giovanni Sanna David P D'Cruz Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Obesity and tobacco smoking are independently associated with poor patient-reported outcomes in SLE: a cross-sectional study
AbstractWe investigated associations of obesity and tobacco smoking with health-related quality of life (HRQoL), pain, fatigue, and functional impairment in systemic lupus erythematosus (SLE). Furthermore, we explored whether there was an effect modification between these two factors. We included adult SLE patients from the Link öping University Hospital (n = 325) in the present cross-sectional analysis. We further included population-based controls and performed cardinality matching to balance age and sex distributions with cases (n = 224). HRQoL was assessed with the EQ-5D index score; pain, fatigue, and overall...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research
The prevalence of neutropenia and association with infections in patients with systemic lupus erythematosus: a Swedish single-center study conducted over 14 years
AbstractHematologic abnormalities are common manifestations of SLE, although neutropenia is observed less frequently and is not included in the classification criteria. Nonetheless, neutropenia is a risk factor for infections, especially those caused by bacteria or fungi. We aimed to evaluate the impact of neutropenia in SLE through a systematic investigation of all infections in a large cohort of well-characterized patients, focusing on neutropenia, lymphopenia, and hypocomplementemia. Longitudinal clinical and laboratory parameters obtained at visits to the Rheumatology Unit, Link öping University Hospital, and linked d...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research
Pancytopenia with aplastic anemia in systemic lupus erythematosus: case series and literature review
We report two cases of SLE patients who presented with pancytopenia, with bone marrow biopsy confirmed AA. One case was treated with cyclophosphamide but unfortunately succumbed to Acute Respiratory Distress Syndrome (ARDS), while the other case was managed with rituximab with a good response. Interestingly, both patients were on azathioprine before the diagnosis of AA. A comprehensive search for reported cases of AA in PubMed, Scopus, and the Directory of Open Access Journals databases was performed to enhance the understanding of the diagnostic and management challenges associated with AA in SLE, facilitating ongoing exp...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research
Quality indicators and satisfaction with care in patients with systemic lupus erythematosus
AbstractGrading the quality of care in patients with systemic lupus erythematosus and determining its relationship with care satisfaction may recognize gaps that could lead to better clinical practice. Eighteen quality indicators (QIs) were recently developed and validated for patients with SLE based on the 2019 EULAR management recommendations. Few studies have analyzed the relationship between quality of care and care satisfaction in patients with lupus. This was a cross-sectional study. We included patients at least 18 years old who met the EULAR/ACR 2019 classification criteria for SLE. We interviewed patients and re...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research
Efficacy of lifestyle interventions in the management of systemic lupus erythematosus: a systematic review of the literature
In conclusion, psychosocial interventions are viable for managing depressive symptoms, and exercise appears essential for reducing fatigue and improving aerobic capacity and physical function. Photoprotection should be recommended to all patients. Lifestyle interventions should be considered a complement, not a substitute, to pharmacotherapy. (Source: Rheumatology International)
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research
Higher odds of periodontitis in systemic lupus erythematosus compared to controls and rheumatoid arthritis: a systematic review, meta-analysis and network meta-analysis
DiscussionGiven that RA is the autoimmune disease classically associated with periodontal disease, the higher odds of having periodontitis in SLE are striking. These results highlight the importance of addressing the dental health needs of patients with SLE.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/ identifier CRD42021272876. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - April 2, 2024 Category: Allergy & Immunology Source Type: research
Synbiotic regulates gut microbiota in patients with lupus nephritis: an analysis using metagenomic and metabolome sequencing
ConclusionSynbiotics regulate the metabolic functions of intestinal microorganisms in patients with LN and play a role in various biological functions. Synbiotic supplements may be safe and promising candidates for patients with LN. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - April 2, 2024 Category: Microbiology Source Type: research
