The impact of Libman-sacks endocarditis on inpatient outcomes with systemic lupus erythematosus: A retrospective study
This study aimed to explore the characteristics and prognosis of SLE patients with LSE and the impact of LSE in patients with SLE on inpatient outcomes including inpatient mortality, length of stay, acute heart failure, atrial fibrillation, and cerebrovascular accidents (CVA).METHODS: This study included adult patients who were hospitalized with SLE between the years 2019 and 2020, using the National Inpatient Sample (NIS) database. The total number of patients with a diagnosis of SLE in the years 2019 and 2020 in the NIS database was 150,411. Of those, 349 had a diagnosis of LSE. The study population was divided into two ...
Source: Lupus - April 2, 2024 Category: Rheumatology Authors: Halah Alfatlawi Abdulmajeed Alharbi Momin Shah Yusuf Nawras Nezam Altorok Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

A predictive model for premature atherosclerosis in systemic lupus erythematosus based on clinical characteristics
CONCLUSIONS: The comprehensive nomogram constructed in this study serves as a useful and convenient tool for evaluating the risk of premature atherosclerosis in SLE patients. It is helpful for clinicians to early identify SLE patients with premature atherosclerosis and facilitates the implementation of more effective preventive measures. Key Points • SLE patients are at a significantly higher risk of developing premature atherosclerosis compared to the general population, and this risk persists even in cases with low disease activity. Traditional models used to evaluate and predict premature atherosclerosis in SLE patien...
Source: Atherosclerosis - April 2, 2024 Category: Cardiology Authors: Ruyu Liang Haojie Xu Ranran Yao Wenwen Pei Ziye Wang Renge Liang Xiao Han Yunshan Zhou Yuan An Yin Su Source Type: research

Combined rituximab and belimumab to treat recalcitrant epidermolysis bullosa aquisita associated with systemic lupus erythematosus
Br J Dermatol. 2024 Apr 2:ljae141. doi: 10.1093/bjd/ljae141. Online ahead of print.NO ABSTRACTPMID:38561894 | DOI:10.1093/bjd/ljae141 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 2, 2024 Category: Dermatology Authors: Thomas J Tull Emma C Benton Kristina Semkova Natalie A Watson John B Mee Begona Lopez Jane Setterfield Barbara Carey Sajjad Ajmad Scott J Robbie Richard W Groves Giovanni Sanna David P D'Cruz Source Type: research

Laboratory assessment of antiphospholipid syndrome: Laboratory data
CONCLUSION: We found several issues with the laboratory workup of APS. This indicates a need for increased awareness of comprehensive laboratory assessment of possible APS as well as a closer collaboration between the laboratory and clinicians.PMID:38563299 | DOI:10.1111/ijlh.14273 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - April 2, 2024 Category: Hematology Authors: Camilla J Kobylecki Signe Vedel-Krogh Shoaib Afzal Jens P Goetze Source Type: research

The impact of Libman-sacks endocarditis on inpatient outcomes with systemic lupus erythematosus: A retrospective study
This study aimed to explore the characteristics and prognosis of SLE patients with LSE and the impact of LSE in patients with SLE on inpatient outcomes including inpatient mortality, length of stay, acute heart failure, atrial fibrillation, and cerebrovascular accidents (CVA).METHODS: This study included adult patients who were hospitalized with SLE between the years 2019 and 2020, using the National Inpatient Sample (NIS) database. The total number of patients with a diagnosis of SLE in the years 2019 and 2020 in the NIS database was 150,411. Of those, 349 had a diagnosis of LSE. The study population was divided into two ...
Source: Lupus - April 2, 2024 Category: Rheumatology Authors: Halah Alfatlawi Abdulmajeed Alharbi Momin Shah Yusuf Nawras Nezam Altorok Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

Combined rituximab and belimumab to treat recalcitrant epidermolysis bullosa aquisita associated with systemic lupus erythematosus
Br J Dermatol. 2024 Apr 2:ljae141. doi: 10.1093/bjd/ljae141. Online ahead of print.NO ABSTRACTPMID:38561894 | DOI:10.1093/bjd/ljae141 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 2, 2024 Category: Dermatology Authors: Thomas J Tull Emma C Benton Kristina Semkova Natalie A Watson John B Mee Begona Lopez Jane Setterfield Barbara Carey Sajjad Ajmad Scott J Robbie Richard W Groves Giovanni Sanna David P D'Cruz Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research

Obesity and tobacco smoking are independently associated with poor patient-reported outcomes in SLE: a cross-sectional study
AbstractWe investigated associations of obesity and tobacco smoking with health-related quality of life (HRQoL), pain, fatigue, and functional impairment in systemic lupus erythematosus (SLE). Furthermore, we explored whether there was an effect modification between these two factors. We included adult SLE patients from the Link öping University Hospital (n = 325) in the present cross-sectional analysis. We further included population-based controls and performed cardinality matching to balance age and sex distributions with cases (n = 224). HRQoL was assessed with the EQ-5D index score; pain, fatigue, and overall...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research

The prevalence of neutropenia and association with infections in patients with systemic lupus erythematosus: a Swedish single-center study conducted over 14  years
AbstractHematologic abnormalities are common manifestations of SLE, although neutropenia is observed less frequently and is not included in the classification criteria. Nonetheless, neutropenia is a risk factor for infections, especially those caused by bacteria or fungi. We aimed to evaluate the impact of neutropenia in SLE through a systematic investigation of all infections in a large cohort of well-characterized patients, focusing on neutropenia, lymphopenia, and hypocomplementemia. Longitudinal clinical and laboratory parameters obtained at visits to the Rheumatology Unit, Link öping University Hospital, and linked d...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research