Kidney grown in lab successfully transplanted into animal
Functioning kidney built from newborn rat cells is a major step towards personalised transplant organs for peopleScientists have grown a kidney in a laboratory and shown that it works when implanted into a living animal. The work is an important step towards the longer-term goal of growing personalised replacement organs that could be transplanted into people with kidney failure.More than 51,000 people are treated every year in the UK for end-stage kidney failure and 90% of those are on the waiting list for organs are waiting for kidneys. A shortage of organs means that every year fewer than 3,000 transplants are carried o...
Source: Guardian Unlimited Science - April 14, 2013 Category: Science Authors: Alok Jha Tags: Tissue engineering World news Health guardian.co.uk Medical research Society UK news Science Source Type: news

Double lung transplant survivor talks about how organ donation saved her life
A year and a half ago Kerry Maletroit was so ill that she was unable to move or breathe for herself. But thanks to a double lung transplant, the Jersey born 30-year-old is fighting fit, saying she has never felt better. (Source: the Mail online | Health)
Source: the Mail online | Health - April 12, 2013 Category: Consumer Health News Source Type: news

Cyclists to raise funds for UCLA Blood and Platelet Center; young patient kicks off race
WHAT:Some 1,000 cyclists will raise funds for the UCLA Blood and Platelet Center while enjoying a fresh-air tour of more than 65 scenic, cultural and historic landmarks in Los Angeles during the 16th annual Volkswagen City of Angels Fun Ride. Riders, who can choose from a 51-mile advanced race or a 31-mile recreational route, will be escorted by Los Angeles Police Department motorcycle officers, with rolling closures of city streets for traffic-free cycling.     Proceeds support UCLA's mobile blood-donation program, which collects 22,000 units of blood a year, supplying half the transfusions for patients at UCLA ...
Source: UCLA Newsroom: Health Sciences - April 10, 2013 Category: Universities & Medical Training Source Type: news

Medtronic’s Affinity Fusion Artificial Lungs for Bypass Surgeries
Medtronic received FDA clearance for its Affinity Fusion blood oxygenation/CO2 removal system for open heart surgeries. The new system was designed with particular engineering attention paid to reducing bubble formation and so preventing air embolisms.The Affinity Fusion was approved in Europe in September of last year and has already been used successfully in the U.S. at the Cleveland Clinic.Read More (Source: Medgadget Anesthesiology)
Source: Medgadget Anesthesiology - April 2, 2013 Category: Anesthesiology Authors: Editors Tags: Anesthesiology Cardiac Surgery Source Type: news

Wearable artificial lung being developed to be a ‘PAAL’
With the support of a $3.4 million National Institutes of Health grant, researchers at the University of Pittsburgh are developing an artificial lung to serve as a bridge to transplant or recovery in patients with acute and chronic lung failure. read more (Source: Articles from MedicalDesign.com)
Source: Articles from MedicalDesign.com - March 26, 2013 Category: Medical Equipment Tags: News Source Type: news

Man who received nation's first 'breathing lung' transplant at UCLA thankful for gift of life
  Fernando Padilla could barely breathe or walk more than a few steps. An incurable disease, pulmonary fibrosis, was causing his lungs to turn to hardened scar tissue, and he was permanently tethered to an oxygen tank. His only hope was a double lung transplant.   In November 2012, he got an early-morning call that a pair of donor lungs was available.   Upon arriving at Ronald Reagan UCLA Medical Center, he was told of a new study testing an experimental device — a portable organ-preservation system that keeps donor lungs functioning and "breathing" in a near-physiologic state outside the bod...
Source: UCLA Newsroom: Health Sciences - March 20, 2013 Category: Universities & Medical Training Source Type: news

Wearable artificial lung to be developed at Pitt through $3.4 million grant
(University of Pittsburgh) With the support of a $3.4 million National Institutes of Health grant, researchers at the University of Pittsburgh will develop an artificial lung to serve as a bridge to transplant or recovery in patients with acute and chronic lung failure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2013 Category: Global & Universal Source Type: news

Copper Detoxification Used As Crafty Defense Mechanism By The Fungus Cryptococcus neoformans
A potentially lethal fungal infection appears to gain virulence by being able to anticipate and disarm a hostile immune attack in the lungs, according to findings by researchers at Duke Medicine. Defense mechanisms used by the fungus Cryptococcus neoformans enable it to lead to fatal meningitis, which is one of the opportunistic infections often associated with death in HIV/AIDS patients, organ transplant recipients, diabetics and other immunosuppressed patients. In describing the complex process of how C... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 18, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Informing relatives of heart or lung transplantation patients
The results of this qualitative study showed a gap between the information and support that relatives to newly listed heart or lung transplant patients need and receive. The professional teams and society in general must better understand the experiences, resources and challenges that the relatives face. More about this study Topics: Cardiovascular Nursing (Source: ESC News and Press)
Source: ESC News and Press - March 15, 2013 Category: Cardiology Source Type: news

UPMC Performs First "Breathing Lung" Transplant On East Coast Using OCS Lung
UPMC surgeons have performed a "breathing lung" transplant using a portable machine that provides a constant supply of blood and nutrients to the donor organs, which doctors say has the potential to keep them healthier and viable for longer than ever before. The double-lung transplant was performed March 4 at UPMC Presbyterian, using the Organ Care System, also known as the OCS lung, by TransMedics Inc. This is the first time the device has been used on the East Coast. The patient, a 53-year-old man from Moundsville, W.Va., had suffered from pulmonary fibrosis and pulmonary hypertension... (Source: Health News fr...
Source: Health News from Medical News Today - March 14, 2013 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

Lung Transplant Hazard May Rise with Obese Recipients, Smoking Donors
Study found more 'primary graft dysfunction,' which is tied to higher death risk Source: HealthDay Related MedlinePlus Pages: Lung Transplantation, Obesity (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 12, 2013 Category: Consumer Health News Source Type: news

‘Bloodless’ Lung Transplants for Jehovah’s Witnesses
Hospitals are working to further innovate “bloodless” operations, both to treat those who shun transfusions and to advance techniques for all patients. (Source: NYT Health)
Source: NYT Health - February 25, 2013 Category: Consumer Health News Authors: By KEVIN SACK Tags: Blood Donation Doctors Tomczak, Rebecca S. Transplants Lungs Jehovah's Witnesses Medicine and Health Wal-Mart Stores Inc WMT NYSE Religion and Belief Source Type: news

Today's Alternative Medicine Accidental Humor
Reiki Master Julie Motz, responding to The Operator, Michael Spector's excellent New Yorker piece on Dr. Oz: I never went near the heart-lung machine, but stood with my hands on the patient’s head for most of the surgery. In heart-transplant surgeries, I would go to the ice chest to (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 23, 2013 Category: Pharmaceuticals Authors: Peter Lipson Source Type: news

Pioneering Stem Cell-Based Transplant Technology Is Being Developed And Tested On New Organs And Tissues
Surgeon Paolo Macchiarini has made his name by successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material. He now plans to use the technique to recreate more complex tissues, such as the oesophagus and diaphragm or organs such as the heart and lungs. He has also made an experimental attempt to regenerate brain in mice and rats. This is part of the news he presented during his seminar at the scientific AAAS Annual Meeting in Boston... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Transplants / Organ Donations Source Type: news

The neuropathology of liver, heart, and heart-lung transplantation
Martinez AJ, Puglia J (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 18, 2013 Category: Respiratory Medicine Source Type: news

Stem cell-based bioartificial tissues and organs
(Karolinska Institutet) Surgeon Paolo Macchiarini has made his name by successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material. He now plans to use the technique to recreate more complex tissues, such as the esophagus and diaphragm or organs such as the heart and lungs. He has also made an experimental attempt to regenerate brain in mice and rats. This is part of the news he will be presenting during his seminar at the scientific AAAS Annual Meeting in Boston. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 18, 2013 Category: Global & Universal Source Type: news

No Early Cancer Risk With Donor Lungs From Heavy Smokers
LOS ANGELES (IMNG) - Use of lungs from donors who smoked heavily does not worsen lung transplantation outcomes including risk for lung cancer death, at least in the medium term.At a median follow-up of... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 15, 2013 Category: Cancer & Oncology Source Type: news

Sherpa Pak Transplant Heart Transport System Gets U.S. Green Light
Paragonix Technologies out of Cambridge, Massachusetts received clearance in the U.S. for the Sherpa Pak Cardiac Transport System. The Sherpa combines oxygenated perfusion of organs and safe organ storage. The device is indicated for hypothermic transportation of hearts in a cold environment for up to four hours in preparation for a transplant. From the announcement:Currently, the availability of cardiac transplantation is governed by the “ischemic time”, that being, the elapsed time from heart donation to recipient implantation. According to The International Society Of Heart and Lung Transplantation...
Source: Medgadget Anesthesiology - February 13, 2013 Category: Anesthesiology Authors: Gene Ostrovsky Tags: Anesthesiology Cardiac Surgery Source Type: news

Infectious complications of lung transplantation. Impact of cystic fibrosis
Flume PA, Egan TM, Paradowski LJ, Detterbeck FC, Thompson JT, Yankaskas JR (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 11, 2013 Category: Respiratory Medicine Source Type: news

Infection after lung transplantation
Paradis IL, Williams P (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 11, 2013 Category: Respiratory Medicine Source Type: news

An unusual presentation of invasive aspergillosis after lung transplantation
Cattelan AM, Loy M, Tognon S, Rea F, Sasset L, Cadrobbi P (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 1, 2013 Category: Respiratory Medicine Source Type: news

Lungs transplants from heavy smokers are 'safe and effective' and could save thousands of lives
It may sound counterintuitive, but lung transplants from people who smoke 20 cigarettes a day can be safe to use, according to scientists from Temple University Hospital in Philadelphia. (Source: the Mail online | Health)
Source: the Mail online | Health - January 30, 2013 Category: Consumer Health News Source Type: news

Lungs from heavy smokers may be okay for transplants
Short and medium-term survival rates were the same for people who received non-smoker and smoker lungs (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - January 30, 2013 Category: Consumer Health News Source Type: news

How to build a bionic man | Corrinne Burns
Rex the bionic man shows how close technology is to catching up with – and exceeding – the abilities of the human bodyHe cuts a dashing figure, this gentleman: nearly seven feet tall, and possessed of a pair of striking brown eyes. With a fondness for Ralph Lauren, middle-class rap and sharing a drink with friends, Rex is, in many ways, an unexceptional chap.Except that he is, in fact, a real-world bionic man. Housed within a frame of state-of-the-art prosthetic limbs is a functional heart-lung system, complete with artificial blood pumping through a network of pulsating modified-polymer arteries. He has a bion...
Source: Guardian Unlimited Science - January 30, 2013 Category: Science Authors: Corrinne Burns Tags: Tissue engineering Robots guardian.co.uk Technology Editorial Science Source Type: news

Smokers’ Lungs May Be Safe for Transplant (CME/CE)
LOS ANGELES (MedPage Today) -- Transplanting a lung from a heavy smoker doesn't appear to hurt the recipient's outcomes over the mid-term, a national registry suggested. (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - January 30, 2013 Category: Journals (General) Source Type: news

Heavy smokers can be successful lung donors
You might think that heavy smokers make for bad lung donors. But a new a study finds donors who smoked more than a pack of cigarettes a day for more than 20 years were strong candidates for double lung transplant donors. (Source: WDSU.com - Health)
Source: WDSU.com - Health - January 30, 2013 Category: Consumer Health News Source Type: news

Study: Lungs From Heavy Smokers OK for Transplant
But recipients need to know the source of the potential transplant, researchers say (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 29, 2013 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Oncology, Pulmonology, Research, Organ Transplants, News, Source Type: news

Study: Lungs from Heavy Smokers OK for Transplant
But recipients need to know the source of the potential transplant, researchers say Source: HealthDay Related MedlinePlus Pages: Lung Transplantation, Organ Donation, Smoking (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 29, 2013 Category: Consumer Health News Source Type: news

Study: Lungs From Heavy Smokers OK for Transplant
Title: Study: Lungs From Heavy Smokers OK for TransplantCategory: Health NewsCreated: 1/29/2013 10:35:00 AMLast Editorial Review: 1/29/2013 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - January 29, 2013 Category: Respiratory Medicine Source Type: news

Study: Lungs From Heavy Smokers OK for Transplant
But recipients need to know the source of the potential transplant, researchers say (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - January 29, 2013 Category: Cancer & Oncology Source Type: news

Flu patients use artificial lungs to heal
TORONTO, Jan. 27 (UPI) -- Toronto General Hospital physicians say they used Extra Corporeal Lung Support -- artificial lungs -- to aid the recovery of five influenza patients. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 28, 2013 Category: Consumer Health News Source Type: news

Shared decision making sheets to facilitate conversations about treatment options
Source: Right Care Area: News The BMJ Group has developed a number of shared decision making sheets, designed to facilitate a conversation between patients and healthcare professionals about the reasons for choosing one treatment option over and above another treatment option. The information sheets are both prompts for use in consultations by health professionals with their patients, and aide-memoires for patients with instructions for accessing the corresponding web-based patient decision aid.    Shared decision making sheets on the following are currently available:   - AAA repair - ...
Source: NeLM - Cardiovascular Medicine - January 22, 2013 Category: Cardiology Source Type: news

Artificial Lung Technology Treatment Normally Used For Lung Transplant Patients Saves Lives Of Critically Ill Flu Patients
In recent weeks the intensive critical care units at University Health Network's Toronto General Hospital have used Extra Corporeal Lung Support (ECLS) to support five influenza (flu) patients in their recovery from severe respiratory problems. ECLS systems are normally used at the hospital as a bridge to lung transplantation but increasingly, the hospital is using ECLS on patients where the usual breathing machines (ventilators) cannot support the patient whose lungs need time to rest and heal... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 21, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

European CHMP to discuss licensing application for defibrotide to treat and prevent hepatic veno-occlusive disease
Source: GlobeNewswire Area: News Gentium S.p.A has announced that its Marketing Authorisation Application (MAA) for defibrotide to treat and prevent hepatic veno-occlusive disease (VOD) in adults and children undergoing haematopoietic stem cell transplantation therapy, will be on the agenda for discussion at the European Medicines Agency's Committee for Medicinal Products for Human Use meetings scheduled to be held on February 18-21, 2013.   Certain high-dose conditioning regimens used as part of stem cell transplantation can damage the lining cells of hepatic blood vessels and result in VOD, a blockage of the sm...
Source: NeLM - News - January 18, 2013 Category: Drugs & Pharmacology Source Type: news

Critically ill flu patients saved with artificial lung technology treatment
In recent weeks, the intensive critical care units at University Health Network's Toronto General Hospital have used Extra Corporeal Lung Support to support five influenza patients in their recovery from severe respiratory problems. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 17, 2013 Category: Science Source Type: news

Simple healing recipes for cleansing your liver and blood
After the heart and lungs, the liver is perhaps your most vital organ. When it shuts down, you die. Extreme liver conditions may result in the eventual need for dangerous liver transplants. A sluggish liver can manifest a malaise of symptoms that lead to misdiagnoses... (Source: NaturalNews.com)
Source: NaturalNews.com - January 17, 2013 Category: Consumer Health News Source Type: news

Critically ill flu patients saved with artificial lung technology treatment
(University Health Network) In recent weeks, the intensive critical care units at University Health Network's Toronto General Hospital have used Extra Corporeal Lung Support to support five influenza patients in their recovery from severe respiratory problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 17, 2013 Category: Global & Universal Source Type: news

Functional Status After Lung Transplantation in Older AdultsFunctional Status After Lung Transplantation in Older Adults
What has changed since the institution of the lung allocation score (LAS) system in 2005 -- for older recipients? American Journal of Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 16, 2013 Category: Consumer Health News Tags: Transplantation Journal Article Source Type: news

New Guidelines Issued For Care Of Mechanical Circulatory Support Device Patients
Mechanical circulatory support (MCS) is a rapidly growing technology used to treat advanced heart failure. Thousands of patients worldwide have now undergone implantation of long- term MCS devices (MCSDs) that can enable them to return home and resume a normal lifestyle. The International Society for Heart and Lung Transplantation (ISHLT) convened an international panel of experts in all aspects of MCS care, which has developed practice guidelines to provide a common framework for the care and treatment of MCS patients... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 11, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news

ISHLT issues new guidelines for care of mechanical circulatory support device patients
(Elsevier Health Sciences) The International Society for Heart and Lung Transplantation convened an international panel of experts in all aspects of mechanical circulatory support care (MCS), a rapidly growing technology to treat advanced heart failure. They developed practice guidelines to provide a common framework for the care and treatment of MCS patients. The Executive Summary of these guidelines is published in the February issue of The Journal of Heart and Lung Transplantation and is freely available. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 10, 2013 Category: Global & Universal Source Type: news

The New Old Age Blog: Who Should Receive Organ Transplants?
A graying population and revised policies determining who gets priority for donated organs have led to a rising proportion of older adults receiving transplants. (Source: NYT Health)
Source: NYT Health - January 8, 2013 Category: Consumer Health News Authors: By PAULA SPAN Tags: University of Michigan eldercare Elderly Transplants Ohio Cleveland Clinic Lungs Medical Issues Age, Chronological organ transplants Organ Donation Source Type: news

Young mother spends her first healthy Christmas with children as double-lung transplant gives her a second chance at life
Thanks to a successful lung transplant operation, Natalie Kerr, 31, from Bolton, was able to enjoy Christmas 2012 with her young children. (Source: the Mail online | Health)
Source: the Mail online | Health - January 2, 2013 Category: Consumer Health News Source Type: news

Medicine: the appliance of science
A cure for HIV? A new approach to obesity? Tailor-made therapies for cancer? Medical science surges aheadMore than once last year, researchers described leaps in medical science that were so breathtaking, and held so much potential for patients, that they immediately joined the list of fields to watch in the year ahead. In most cases, the work was, and is, at an early stage and its future success far from certain. Such is the nature of science. Most of today's breakthroughs will be tomorrow's failures. But some may go down in history for transforming how medicine is done.Often, medical science surges ahead when different a...
Source: Guardian Unlimited Science - January 1, 2013 Category: Science Authors: Ian Sample Tags: The Guardian Genetics Biology Medical research Microbiology Society Features Cancer Aids and HIV Chemistry Biochemistry and molecular biology Science Source Type: news

Thoracic Organ Transplantation: Laboratory Methods
Although great progress has been achieved in thoracic organ transplantation through the development of effective immunosuppression, there is still significant risk of rejection during the early post-transplant period, creating a need for routine monitoring for both acute antibody and cellular mediated rejection. The currently available multiplexed, microbead assays utilizing solubilized HLA antigens afford the capability of sensitive detection and identification of HLA and non-HLA specific antibodies. These assays are being used to assess the relative strength of donor specific antibodies; to permit performance of virtual ...
Source: Springer protocols feed by Immunology - January 1, 2013 Category: Allergy & Immunology Source Type: news

Revised Article-Total Artificial Heart
A total artificial heart is a device that replaces the two lower chambers of the heart. (Source: National Heart, Lung, and Blood Institute Health Topics)
Source: National Heart, Lung, and Blood Institute Health Topics - July 6, 2012 Category: Consumer Health News Source Type: news

New Clinical Advisory: Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intensity in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia (BMT CTN 0901)
The National Institutes of Health's National Heart, Lung, and Blood Institute has suspended enrollment for the clinical study BMT CTN 0901 conducted by the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) after preliminary data appeared to show benefit for one approach to the intensity of conditioning for allogeneic stem cell transplantations in patients eligible for the study. (Source: PubMed New and Noteworthy)
Source: PubMed New and Noteworthy - June 18, 2012 Category: Databases & Libraries Source Type: news

New Clinical Advisory: Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intensity in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia (BMT CTN 0901)
​The National Institutes of Health’s National Heart, Lung, and Blood Institute has suspended enrollment for the clinical study BMT CTN 0901 conducted by the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) after preliminary data appeared to show benefit for one approach to the intensity of conditioning for allogeneic stem cell transplantations in patients eligible for the study. (Source: PubMed New and Noteworthy)
Source: PubMed New and Noteworthy - June 18, 2012 Category: Databases & Libraries Source Type: news

Summaries: International Kidney Cancer Symposium
Conclusion: there is no increased risk of doing the lymph node dissection early on.   Dr. Eggener-CON   Basics Lymph node dissections rarely done, even for large tumors, because there is no proven therapeutic or staging benefit for low risk patients.  A Mayo study revealed no data showing therapeutic benefit in high risk patients.  For clinically node negative high risk patients, there is staging value but no proven therapeutic benefit. Rate of positive nodes is associated with stage and grade; the higher the stage and grade, the more likely there will be positive nod...
Source: Kidney Cancer Association - November 29, 2011 Category: Urology & Nephrology Source Type: news

Revised Article-Lung Transplant
A lung transplant is surgery to remove a person's diseased lung and replace it with a healthy lung from a deceased donor. (Source: National Heart, Lung, and Blood Institute Health Topics)
Source: National Heart, Lung, and Blood Institute Health Topics - May 25, 2011 Category: Consumer Health News Source Type: news

Revised Article-Total Artificial Heart
A total artificial heart (TAH) is a device that replaces the two lower chambers of the heart. (Source: National Heart, Lung, and Blood Institute Health Topics)
Source: National Heart, Lung, and Blood Institute Health Topics - June 23, 2010 Category: Consumer Health News Source Type: news