Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Investigating the association between a history of depression and biomarkers of Alzheimer ’s disease, cerebrovascular disease, and neurodegeneration in patients with dementia
This study aimed to investigate the relationship between a history of depression and biomarkers of AD and CVD in patients with dementia in a clinical setting. A total of 126 patients from the University Health N etwork (UHN) Memory Clinic with comprehensive clinical evaluations, including neuropsychological testing and medical examinations, were included. Lumbar puncture was performed to collect cerebrospinal fluid (CSF) for biomarker analysis, and brain magnetic resonance imaging (MRI) scans were obtained to assess white matter hyperintensity (WMH) burden. The presence of depression was determined through medical records....
Source: AGE - December 14, 2023 Category: Geriatrics Source Type: research

Preferences of Patients with Amyotrophic Lateral Sclerosis for Intrathecal Drug Delivery: Choosing between an Implanted Drug-Delivery Device and Therapeutic Lumbar Puncture
ConclusionPatients considered an IDDD as a valuable alternative to LP in multiple clinical settings. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - December 14, 2023 Category: International Medicine & Public Health Source Type: research