Acute-Onset Lower Extremity Weakness and Urinary Retention in a Chronically Immunosuppressed Patient: Diagnosis and Management of Herpes Simplex Virus Type 2 Myelitis
Cureus. 2024 Feb 29;16(2):e55248. doi: 10.7759/cureus.55248. eCollection 2024 Feb.ABSTRACTA 34-year-old immunosuppressed male presented with worsening bilateral lower extremity weakness and urinary retention accompanied by a painless clean-based chancre on his glans penis. Physical examination revealed symmetrically diminished lower extremity weakness most pronounced with hip flexion and knee extension and absent Achilles reflexes. Full MRI spine without contrast was noncontributory. Lumbar puncture showed elevated protein and total nucleated cells with lymphocytic predominance. Both CSF and serum polymerase chain reaction...
Source: Herpes - April 1, 2024 Category: Infectious Diseases Authors: Jaya Chandra Hamid R Khatibi Source Type: research

Stenotrophomonas maltophilia neonatal sepsis: a case report
ConclusionsThis report describes a neonatal sepsis case caused byS. maltophilia, a multi-drug resistant bacteria and a rare cause of neonatal sepsis. We report that early detection of the bacterial and antimicrobial management based on local antibiogram data may be essential for successful patient ’s management. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 25, 2024 Category: General Medicine Source Type: research

Diurnal cortisol, neuroinflammation, and neuroimaging visual rating scales in memory clinic patients
CONCLUSION: This study suggests an interplay between diurnal cortisol patterns and neuroinflammation in relation to brain structure. While this cross-sectional study does not provide information on causality or temporality, these findings suggest that neuroinflammation may be involved in the relationship between HPA-axis functioning and AD.PMID:38503394 | DOI:10.1016/j.bbi.2024.03.024 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - March 19, 2024 Category: Neurology Authors: Jasper Holleman Makrina Daniilidou Ingemar K åreholt Malin Asp ö G öran Hagman Chinedu T Udeh-Momoh Gabriela Spulber Miia Kivipelto Alina Solomon Anna Matton Shireen Sindi Source Type: research

Diurnal cortisol, neuroinflammation, and neuroimaging visual rating scales in memory clinic patients
CONCLUSION: This study suggests an interplay between diurnal cortisol patterns and neuroinflammation in relation to brain structure. While this cross-sectional study does not provide information on causality or temporality, these findings suggest that neuroinflammation may be involved in the relationship between HPA-axis functioning and AD.PMID:38503394 | DOI:10.1016/j.bbi.2024.03.024 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - March 19, 2024 Category: Neurology Authors: Jasper Holleman Makrina Daniilidou Ingemar K åreholt Malin Asp ö G öran Hagman Chinedu T Udeh-Momoh Gabriela Spulber Miia Kivipelto Alina Solomon Anna Matton Shireen Sindi Source Type: research

Spinal adhesive arachnoiditis after spinal anesthesia complicated by communicating hydrocephalus - A case report
CONCLUSION: AA is a challenging condition associated with inflammation and scarring of the arachnoid membrane. The development of hydrocephalus following epidural anesthesia, in this case, highlights a rare manifestation of arachnoiditis. Further research and documentation are needed to understand better the underlying mechanisms and risk factors contributing to hydrocephalus in the context of AA following epidural anesthesia.PMID:38468646 | PMC:PMC10927229 | DOI:10.25259/SNI_933_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - March 12, 2024 Category: Neurosurgery Authors: Abdulrahman Marzouq AlMutairi Mubasher Ahmed Abdulaziz Abdullah Basurrah Fayez Dhafer Alshehri Zaina Brinji Naseem Albargi Ahmed Adel Farag Source Type: research