Effect of Various Ancillary Operating Room Techniques on Wound Healing Outcomes After Total Hip Arthroplasty
CONCLUSION: Wound healing post THA is a complex process, influenced by various surgical techniques and intraoperative decisions. This systematic review meticulously examined three critical factors: the role of DVT prophylaxis, the implications of intraoperative drain usage, and the impact of different surgical approaches. Our analysis revealed that rivaroxaban and enoxaparin exhibit similar wound infection rates in THA. The decision to use intraoperative drains in the current literature indicates no definite advantage or disadvantage regarding wound problems with the use of closed-suction drainage in THA. In exploring surg...
Source: Surgical Technology International - January 3, 2024 Category: Surgery Authors: Daniel Hameed Jeremy A Dubin Sandeep S Bains Tim Board Ryan Nunley Michael A Mont Source Type: research
Calibration-free electrochemical sensor to monitor factor-Xa inhibitors at the point-of-care anticoagulation therapy
This article presents a novel proof of concept for the blood plasma quantification of clinically relevant concentrations of direct oral anticoagulants, DOACs, including rivaroxaban and edoxaban, as well as low-molecular-weight heparins, LMWHs, such as enoxaparin and dalteparin, utilising a calibration-free disposable electrochemical sensor with co-facing electrodes. A dose-response curve was generated for rivaroxaban and edoxaban to demonstrate the sensor's ability to detect ≥9.00 ng mL-1 rivaroxaban and quantify it in the 11.0-140 ng mL-1 range. Similarly, the lower detection limit for edoxaban was 12.9 ng mL-1, with a ...
Source: Talanta - December 30, 2023 Category: Chemistry Authors: Ashwin K V Mruthunjaya Ronald C Chatelier Angel A J Torriero Source Type: research
Multicenter study evaluating target attainment of anti ‐Factor Xa levels using various enoxaparin prophylactic dosing practices in adult trauma patients
This study compared BMI-, TBW-, EBV-based, and hybrid enoxaparin dosing strategies at achieving target prophylactic anti-Factor Xa (anti-Xa) levels in trauma patients.This was a multicenter, retrospective review of adult trauma patients who received enoxaparin twice daily for VTE prophylaxis and had at least one appropriately timed anti-Xa level (collected 3 to 6 hours after the previous dose after three consecutive doses) from January 2017 through December 2020. Patients were excluded if the hospital-specific dosing protocol was not followed or if they had thermal burns with> 20% body surface area involvement. The p...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 27, 2023 Category: Drugs & Pharmacology Authors: Tyler Chanas,
Gabrielle Gibson,
Elizabeth Langenstroer,
David J. Herrmann,
Thomas W. Carver,
Kaitlin Alexander,
Sai Ho Jason Chui,
Lisa Rein,
Michael Ha,
Kaylee M. Maynard,
Kristen Bamberg,
Mary O ’Keefe,
Marisa O’Brien,
Mariela Cardona G Tags: RESEARCH ARTICLE Source Type: research
Clinical outcomes associated with anti ‐Xa‐monitored enoxaparin for venous thromboembolism prophylaxis
ConclusionsThirty-day clinical outcomes in patients receiving enoxaparin for VTE prophylaxis were not improved by anti-Xa monitoring. Our results support current evidence-based guideline recommendations against anti-Xa monitoring for patients receiving enoxaparin for VTE prophylaxis. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 26, 2023 Category: Drugs & Pharmacology Authors: John A. Saunders,
Sara R. Vazquez,
Joseph A. Hill,
Daniel M. Witt Tags: RESEARCH ARTICLE Source Type: research
Clinical outcomes associated with anti ‐Xa‐monitored enoxaparin for venous thromboembolism prophylaxis
ConclusionsThirty-day clinical outcomes in patients receiving enoxaparin for venous thromboembolism prophylaxis were not improved by anti-Xa monitoring. Our results support current evidence-based guideline recommendations against anti-Xa monitoring for patients receiving enoxaparin for venous thromboembolism prophylaxis. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 13, 2023 Category: Drugs & Pharmacology Authors: John A. Saunders,
Sara R. Vazquez,
Joseph A. Hill,
Daniel M. Witt Tags: RESEARCH ARTICLE Source Type: research
Factors associated with venous thromboembolic disease due to failed thromboprophylaxis
CONCLUSION: Our study suggests that the failed thromboprophylaxis is associated with high BMI, active cancer, leukocytosis, and ICU requirement. Future studies should evaluate whether there is benefit in adjusting the thromboprophylaxis scheme in patients with one or more of these factors.PMID:38057785 | DOI:10.1186/s12959-023-00566-4 (Source: Cancer Control)
Source: Cancer Control - December 7, 2023 Category: Cancer & Oncology Authors: Santiago Grillo P érez Paula Ruiz-Talero Oscar Mauricio Mu ñoz Velandia Source Type: research
Cannabis Arteritis and Recurrent Phlebitis
A previously healthy man in his late 30s presented with a 4-year history of ultrasound-confirmed recurrent upper and lower extremity superficial vein thrombosis (SVT) despite therapeutic apixaban, rivaroxaban, or enoxaparin (Figure 1). Although a lifelong nonuser of tobacco, he smoked marijuana daily for 20 years. With abstinence, the frequency of recurrent SVT resolved. Upon re-exposure, SVT recurred. Neither deep venous thrombosis nor pulmonary embolism was observed. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - December 1, 2023 Category: Internal Medicine Authors: Robert D. McBane, Matthew J. Koster Tags: Medical image Source Type: research
Erratum to: Glomerular filtration rate estimated by Cockcroft-Gault formula better predicts anti-Xa levels than Modification of the diet in renal disease equation in older patients with prophylactic enoxaparin
(Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - December 1, 2023 Category: Nutrition Source Type: research
Current practices in pediatric hospital-acquired thromboembolism: Survey of the Children's Hospital Acquired Thrombosis (CHAT) Consortium
CONCLUSION: Practices among institutions are variable in regard to use of HA-VTE prophylaxis, risk assessment, or guideline implementation, highlighting the need for further research and a validated risk assessment model through groups like the CHAT Consortium.PMID:38024326 | PMC:PMC10656282 | DOI:10.1002/rth2.12793 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - November 29, 2023 Category: Hematology Authors: Christina M Abrams Julie Jaffray Amy Stillings Brian R Branchford Guy Young Neil A Goldenberg Yasmina L Abajas CHAT Consortium Investigators VTE Risk Factors and Thromboprophylaxis Working Group of the Pediatric and Neonatal Thrombosis and Hemostasis Subc Source Type: research
Event rates and risk factors for venous thromboembolism and major bleeding in a population of hospitalized adult patients with acute medical illness receiving enoxaparin thromboprophylaxis
CONCLUSION: There is substantial heterogeneity in the event rates for VTE and major bleeding in acute medically ill patients. History of VTE and cancer related hospitalization represent profiles with a high risk of VTE, where continued VTE prophylaxis may be warranted.PMID:38030465 | DOI:10.1016/j.ejim.2023.11.017 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 29, 2023 Category: Internal Medicine Authors: Gr égoire Le Gal Giancarlo Agnelli Harald Darius Susan R Kahn Tarek Owaidah Ana Thereza Rocha Zhenguo Zhai Irfan Khan Yasmina Djoudi Ekaterina Ponomareva Alexander T Cohen Source Type: research
Current practices in pediatric hospital-acquired thromboembolism: Survey of the Children's Hospital Acquired Thrombosis (CHAT) Consortium
CONCLUSION: Practices among institutions are variable in regard to use of HA-VTE prophylaxis, risk assessment, or guideline implementation, highlighting the need for further research and a validated risk assessment model through groups like the CHAT Consortium.PMID:38024326 | PMC:PMC10656282 | DOI:10.1002/rth2.12793 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - November 29, 2023 Category: Hematology Authors: Christina M Abrams Julie Jaffray Amy Stillings Brian R Branchford Guy Young Neil A Goldenberg Yasmina L Abajas CHAT Consortium Investigators VTE Risk Factors and Thromboprophylaxis Working Group of the Pediatric and Neonatal Thrombosis and Hemostasis Subc Source Type: research
Event rates and risk factors for venous thromboembolism and major bleeding in a population of hospitalized adult patients with acute medical illness receiving enoxaparin thromboprophylaxis
CONCLUSION: There is substantial heterogeneity in the event rates for VTE and major bleeding in acute medically ill patients. History of VTE and cancer related hospitalization represent profiles with a high risk of VTE, where continued VTE prophylaxis may be warranted.PMID:38030465 | DOI:10.1016/j.ejim.2023.11.017 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 29, 2023 Category: Internal Medicine Authors: Gr égoire Le Gal Giancarlo Agnelli Harald Darius Susan R Kahn Tarek Owaidah Ana Thereza Rocha Zhenguo Zhai Irfan Khan Yasmina Djoudi Ekaterina Ponomareva Alexander T Cohen Source Type: research
Event rates and risk factors for venous thromboembolism and major bleeding in a population of hospitalized adult patients with acute medical illness receiving enoxaparin thromboprophylaxis
CONCLUSION: There is substantial heterogeneity in the event rates for VTE and major bleeding in acute medically ill patients. History of VTE and cancer related hospitalization represent profiles with a high risk of VTE, where continued VTE prophylaxis may be warranted.PMID:38030465 | DOI:10.1016/j.ejim.2023.11.017 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 29, 2023 Category: Internal Medicine Authors: Gr égoire Le Gal Giancarlo Agnelli Harald Darius Susan R Kahn Tarek Owaidah Ana Thereza Rocha Zhenguo Zhai Irfan Khan Yasmina Djoudi Ekaterina Ponomareva Alexander T Cohen Source Type: research
The Treatment of Venous Thromboembolism in the Emergency Department in the DOACs Era
CONCLUSIONS: Clinician training regarding discharge of VTE patients from the ED should continue.PMID:37980618 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - November 19, 2023 Category: General Medicine Authors: Ibrahim Osman Alaa Atamna Avishay Elis Source Type: research
