Heart cells beating in a Petri dish offer new hope to heart patients
Ingenious use of stem cell research brings treatment for incurable condition closerAdele Johnson was 26 when she was involved in a motorway accident in 2009. She sustained only minor injuries and was able to walk away from the crash. But several weeks later she still felt stressed, tired and depressed.Johnson's condition initially baffled doctors, but a cardiologist provided a diagnosis: she had long QT syndrome, an incurable, potentially lethal inherited heart condition."It had never been spotted and it was only later, when the rest of my family was tested, that we discovered that my father and two of my three sisters als...
Source: Guardian Unlimited Science - February 2, 2014 Category: Science Authors: Robin McKie Tags: Biology News Medical research Human biology UK news Stem cells The Observer Science Source Type: news

Diagnosing lethal heart rhythm in the womb
A promising technology may enable doctors to diagnose and possibly treat in utero a common cause of stillbirth and sudden death in infants, according to research published in the American Heart Association journal Circulation. The study is the first to document the electrophysiological characteristics of fetal long QT syndrome and to evaluate the diagnostic accuracy of the magnetic EKG, or magnetocardiogram, in a sizable population of at-risk fetuses. "Until now, physicians were unable to diagnose a serious heart condition known as long QT syndrome until after birth," said Ronald T... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 13, 2013 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

Magnetic ECG Sees Faulty Fetal Heart Rhythm (CME/CE)
(MedPage Today) -- Checking fetal heart rhythms with magnetocardiography -- described as the "magnetic analog of ECG" -- may be able to diagnose long QT syndrome and allow intervention before the baby is born, researchers found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2013 Category: Cardiology Source Type: news

Patient-specific cure discovered for dangerous heart rhythm disorder Long QT syndrome 2
The National Heart Centre Singapore (NHCS) research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 (LQTS 2) in patient-specific heart cells, scoring a world's first. Long QT syndrome 2 is a dangerous heart rhythm disorder that can lead to sudden cardiac death, even in young patients. It is caused by a mutation in a specific gene known as hERG, which helps to control the electrical activity in the heart cells and coordinate its beating rhythm... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 20, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

National Heart Centre Singapore discovers patient-specific cure for dangerous heart rhythm disorder
(SingHealth) A National Heart Centre Singapore research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 in patient-specific heart cells, scoring a world's first. This novel experiment paves the way for the better understanding on how drugs affect cell and intra-cell disordered function and allows safe testing of new compounds on patients' own cells, without the risk of side effects to the patients themselves. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2013 Category: Global & Universal Source Type: news

Cigna to Preauthorize Genetic Tests
Clinical laboratories and pathology groups serving Cigna beneficiaries can expect to see new requirements for genetic tests used to diagnose breast cancer, colon cancer and long QT syndrome Effective this week, Cigna¬†(NYSE: CI) in Bloomfield, Connecticut, is implementing a new program that requires genetic counseling and pre-authorization for certain genetic tests. This is an important […] (Source: Dark Daily)
Source: Dark Daily - September 16, 2013 Category: Laboratory Medicine Authors: Barbara Tags: Coding, Billing, and Collections Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Sales and Marketing Management & Operations News From Dark Daily Amber Trevidi breast cancer ci Source Type: news

What Are Indications for Pediatric Pacemakers?
Discussion More pediatric patients are having cardiac pacemakers and implantable cardioverter defibrillators (ICDs) placed because the devices are becoming smaller and are technically feasible plus the surgical complexity of patients also keeps increasing. Pacemakers have an impulse generator and leads. The leads can be placed uni- or bilaterally and are attached to the endo- or epicardium. The generator is placed in the left pectoral area. Complications include lead dislodgement or breakage, and inappropriate shocks. Other problems include need for lead or generator revisions, lifestyle modifications, and cosmetic changes...
Source: PediatricEducation.org - July 7, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Long QT Syndrome, ICD and Competitive Sport ParticipationLong QT Syndrome, ICD and Competitive Sport Participation
Should LQTS patients participate in competitive sports? This editorial explores the medical and ethical issues. British Journal of Sports Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 27, 2013 Category: Consumer Health News Tags: Orthopaedics Journal Article Source Type: news

Drinking only soda for 16 years linked to woman's heart woes
Case report detailed 31-year-old woman who developed "long QT syndrome" after cola habit (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - June 25, 2013 Category: Consumer Health News Source Type: news

Study Links Stillbirth to Genes Tied to Dangerous Heart Rhythm
Variation seen in 'long QT syndrome' found in nearly 20 percent of casesSource: HealthDay Related MedlinePlus Pages: Arrhythmia, Stillbirth (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 11, 2013 Category: Consumer Health News Source Type: news

Mayo Clinic, U.S. and European Researchers Find Heart Disorder Genetic Variants in Stillbirth Cases
In a first-of-its-kind study, researchers from the United States and Europe discovered genetic mutations associated with long QT syndrome (LQTS), a genetic abnormality in the heart's electrical system, in a small number of intrauterine fetal deaths, according to a study in the April 10 issue of the Journal of the American Medical Association. (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 10, 2013 Category: Databases & Libraries Authors: Mayo Clinic Source Type: news

Mayo Clinic, U.S. and European Researchers Find Heart Disorder Genetic Variants in Stillbirth Cases
In a first-of-its-kind study, researchers from the United States and Europe discovered genetic mutations associated with long QT syndrome (LQTS), a genetic abnormality in the heart's electrical system, in a small number of intrauterine fetal deaths, according to a study in the April 10 issue of the Journal of the American Medical Association. (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 10, 2013 Category: Research Authors: Mayo Clinic Source Type: news

Mayo Clinic, U.S. and European Researchers Find Heart Disorder Genetic Variants in Stillbirth Cases
In a first-of-its-kind study, researchers from the United States and Europe discovered genetic mutations associated with long QT syndrome (LQTS), a genetic abnormality in the heart's electrical system, in a small number of intrauterine fetal deaths, according to a study in the April 10 issue of the Journal of the American Medical Association. (Source: Mayo Clinic Rochester News)
Source: Mayo Clinic Rochester News - April 10, 2013 Category: Hospital Management Authors: Mayo Clinic Source Type: news

Lost Pregnancies Linked to Long QT Mutations (CME/CE)
(MedPage Today) -- At least some unexplained miscarriages and stillbirths appear to be associated with mutations in genes for long QT syndrome susceptibility, researchers found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 10, 2013 Category: Cardiology Source Type: news

Genetic Variants Of Heart Disorder Discovered In Some Cases Of Stillbirth
In a molecular genetic evaluation involving 91 cases of intrauterine fetal death, mutations associated with susceptibility to long QT syndrome (LQTS; a heart disorder that increases the risk for an irregular heartbeat and other adverse events) were discovered in a small number of these cases, preliminary evidence that may provide insights into the mechanism of some intrauterine fetal deaths, according to a study in the April 10 issue of JAMA, a Genomics theme issue. "Intrauterine fetal death is a major public health problem... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 9, 2013 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news