Killing brain cells and skin cells simultaneously with inhalant abuse: pearls from the National Burn Repository - Kahn SA, Bierman TV, Larson KJ, Blache AL.
BACKGROUND: Over 20 million Americans have abused inhalants at least once in their lifetime. It is widely known that 'huffing' increases risk for liver disease, renal failure, hypoxia, respiratory failure, dysrhythmias, and cardiac arrest. However, it is l... (Source: SafetyLit)
Source: SafetyLit - February 28, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Researchers identify potential mechanism to control nonalcoholic fatty liver disease
FINDINGSIn a comprehensive, nine-year-long study in mice, researchers profiled more than 300 liver and plasma lipid species and more than 5,000 liver proteins. The combined data helped researchers to identify new mechanisms that control the metabolism of lipids (molecules that include fat) and to discover a protein that regulates lipids. They found that silencing one particular protein, called PSMD9, is a potential therapeutic strategy to reduce nonalcoholic fatty liver disease.BACKGROUNDNonalcoholic fatty liver disease is the buildup of excess fat in liver cells not caused by alcohol. The disease affects about 25 percent ...
Source: UCLA Newsroom: Health Sciences - February 28, 2019 Category: Universities & Medical Training Source Type: news

Liver Transplant Saves Critically Ill Patient
Treatment TermsAutoimmune HepatitisLiver transplant Overview Ray Thompson was a teenager when doctors first suspected something was wrong with his liver. He was an adult when he learned his condition was autoimmune hepatitis, a chronic disease in which the body ’s immune system attacks the liver. He kept it under control, but his luck ran out two years ago -- when he became so ill that he needed a liver transplant. While researching liver transplant programs, his wife discovered Duke was one of the best. Thompson was evaluated for the transplant and plac ed on the waitlist within one week of his first appointment. ...
Source: dukehealth.org: Duke Health News - February 27, 2019 Category: Consumer Health News Authors: dg62 at duke.edu Source Type: news

Estimating Liver Fibrosis in HCV: Serum Markers vs TE Estimating Liver Fibrosis in HCV: Serum Markers vs TE
This study compared the diagnostic accuracy of a panel of noncommercial serum scores to transient elastography for determining the extent of hepatic fibrosis in HCV patients on DAA-based therapy.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 27, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Moms, add more leucine and omega-3s to your diet to boost antioxidant levels in your children's liver
(Natural News) Expectant mothers need a wide range of nutrients for them and their child to stay healthy. Fortunately, there are many supplements that can help them achieve proper nutrition. In a study by researchers from the University of Campinas in Sao Paulo, Brazil, they found that supplementing a maternal diet with leucine and omega-3 is beneficial for the... (Source: NaturalNews.com)
Source: NaturalNews.com - February 27, 2019 Category: Consumer Health News Source Type: news

Gene therapy trials point to cure for rare liver disease
EU-funded researchers are close to developing a cure for Crigler-Najjar syndrome, an extremely rare, life-threatening liver disease. The groundbreaking research, currently being validated in clinical trials, could also pave the way for the treatment of other genetic disorders. (Source: EUROPA - Research Information Centre)
Source: EUROPA - Research Information Centre - February 27, 2019 Category: Research Source Type: news

Keytruda May Help Put Melanoma Into Remission
Keytruda is the drug responsible for the remission of former President Jimmy Carter's cancer in 2015. Carter, then 90, had melanoma that spread to his brain and liver. Treatment with Keytruda appears to have cured him. (Source: WebMD Health)
Source: WebMD Health - February 26, 2019 Category: Consumer Health News Source Type: news

3D printing reduces liver transplant costs, surgery time
Presurgical planning on 3D-printed models allowed researchers from China to...Read more on AuntMinnie.comRelated Reading: 3D printing unites radiology, otolaryngology 3D printing helps separate rare case of conjoined twins 3D printing gives pediatric heart surgery a boost 3D-printed lungs improve patient understanding of surgery 3D printing boosts efficiency of rib fracture repair (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 26, 2019 Category: Radiology Source Type: news

More Babies Are Being Born With Syphilis. Blame Meth and Opioids.
Details the connection between drug use, the opioid epidemic, and the significant rise in syphilis and syphilis among newborns, or congenital syphilis. Some of the communities hit hardest by the opioid epidemic and a related methamphetamine spike are also the location of some of the steepest increases in syphilis. Congenital syphilis can cause deformities, severe anemia, an enlarged liver and spleen, jaundice or brain and nerve problems like blindness or deafness, and up to 40% may be stillborn or die as a newborn. (Source: News stories via the Rural Assistance Center)
Source: News stories via the Rural Assistance Center - February 26, 2019 Category: Rural Health Source Type: news

Drug-induced liver injury caused by kratom use as an alternative pain treatment amid an ongoing opioid epidemic - Osborne CS, Overstreet AN, Rockey DC, Schreiner AD.
Kratom ( Mitragyna speciosa) is a prevalent medicinal plant used mainly for the stimulant and analgesic properties provided through multiple alkaloid compounds. Over the past decade, use of kratom has increased despite the limited knowledge of toxicities a... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Eating Whole Grains Tied to Lower Liver Cancer
Eating More Whole Grains Tied to Lower Liver Cancer Risk (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 25, 2019 Category: General Medicine Source Type: news

Factors Influencing Delayed Onset of Symptoms in DILI Factors Influencing Delayed Onset of Symptoms in DILI
Why do some instances of drug-induced liver injury manifest days or weeks after drug cessation?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 25, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Deborah James: My most painful decision - should I die in my own home?
I’m 37 and I have incurable bowel cancer. It’s spread to my liver and lungs. I was diagnosed three years ago, I have just an 8% chance of being alive in 2021. (Source: the Mail online | Health)
Source: the Mail online | Health - February 23, 2019 Category: Consumer Health News Source Type: news

Company may have leaked carcinogen into air for years
Breathing in high concentrations of the chemical TCE has been linked to kidney cancer, liver cancer and lymphoma (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 22, 2019 Category: Consumer Health News Source Type: news

Eating More Whole Grains Tied to Lower Liver Cancer Risk Eating More Whole Grains Tied to Lower Liver Cancer Risk
Higher intake of whole grains was associated with reduced risk of hepatocellular carcinoma (HCC) in a large, long follow-up cohort study.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 22, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Nonalcoholic fatty liver disease, commonly associated with diabetes, increases the risk of heart disease, and liver, colorectal, and breast cancers
(Natural News) In a new study that was published in the Journal of Hepatology, researchers were able to surmise that nonalcoholic fatty liver disease (NAFLD) is not only associated with hepatocellular carcinoma (HCC), but also to cancers that have nothing to do with the liver, such as colorectal and breast cancers. “NAFLD is a very... (Source: NaturalNews.com)
Source: NaturalNews.com - February 21, 2019 Category: Consumer Health News Source Type: news

Whole grains might help ward off liver cancer
(Reuters Health) - Yet another benefit of eating a diet containing high amounts of whole grains may be a reduced risk of liver cancer, a new U.S. study suggests. (Source: Reuters: Health)
Source: Reuters: Health - February 21, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

A diet rich in whole grains slashes risk of liver cancer by 40%, study finds
US researchers tracked 77,241 women and 48,214 men in their 50s and 60s for 24 years. Those with higher intake of whole grains, bran and cereal fiber had a lower risk of liver cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - February 21, 2019 Category: Consumer Health News Source Type: news

More Young Women Are Having Heart Attacks, Study Says. This Could Be Why
Younger women are having more heart attacks, and accounted for nearly a third of all female heart attack patients in recent years, according to a recent study. The news compounds a string of recent findings that have pointed to poorer overall health for young American women. “Women now, compared to younger women generations before them, are less healthy,” says study co-author Melissa Caughey, a cardiovascular epidemiologist and instructor at the University of North Carolina Chapel Hill School of Medicine. “It’s probably reflective of poorer health in general.” The study, which appeared in a sp...
Source: TIME: Health - February 21, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime Research Source Type: news

Researchers discover a genetic defect linked to pediatric liver disease
(University of Colorado Anschutz Medical Campus) Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to biliary atresia (BA), the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2019 Category: International Medicine & Public Health Source Type: news

Could whole grains, dietary fiber be associated with lower risk of liver cancer?
(JAMA Network) This   study used data for participants followed-up for 24 years as part of two well-known study groups to examine the association between whole grain and dietary fiber intake with the risk of hepatocellular carcinoma, a predominant form of liver cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2019 Category: Cancer & Oncology Source Type: news

Field elm guards against liver damage, gastric ulcer, and hypertension
(Natural News) A study has found that extracts from the bark of field elm (Ulmus campestris) tree have protective effects against liver damage, arterial damage, and gastric ulcer. The study, which was published in the journal Phytothérapie, also revealed that the extracts possess strong antioxidant properties. Researchers from the University of Bejaia and the University of... (Source: NaturalNews.com)
Source: NaturalNews.com - February 21, 2019 Category: Consumer Health News Source Type: news

Intercept's Drug for Liver Fibrosis Due to NASH Meets Main Goal Intercept's Drug for Liver Fibrosis Due to NASH Meets Main Goal
Intercept Pharmaceuticals Inc said on Tuesday its treatment in patients with nonalcoholic steatohepatitis (NASH) showed an improvement in liver fibrosis, taking the drug a step closer to approval.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 20, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Fraunhofer MEVIS presents AI at SPIE meeting
German research organization Fraunhofer Institute for Digital Medicine (MEVIS)...Read more on AuntMinnie.comRelated Reading: Germany's rising stars step into limelight at RSNA CARS report: Liver segmentation tool allows manual fixes (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 20, 2019 Category: Radiology Source Type: news

Merck's Keytruda fails late-stage study in liver cancer patients
Merck& Co Inc said on Tuesday its cancer drug Keytruda failed the main goals of a late-stage trial and did not extend life of patients with a type of liver cancer. (Source: Reuters: Health)
Source: Reuters: Health - February 19, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Girl, six, has rare liver disease that causes her skin to be itchy all the time
Clara Peterson, six, from Green Acres, Washington, was diagnosed when she was an infant with a disease that causes bile salts to build up in liver cells instead of being excreted. (Source: the Mail online | Health)
Source: the Mail online | Health - February 19, 2019 Category: Consumer Health News Source Type: news

Intercept's fatty liver drug meets late-stage main goal, shares soar
Intercept Pharmaceuticals Inc said on Tuesday its treatment in patients with a progressive fatty liver disease showed an improvement in scarring on the organ, taking the drug a step closer to approval and sending the company's shares surging 25 percent. (Source: Reuters: Health)
Source: Reuters: Health - February 19, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

A naturally-occurring plant compound shows great potential for treating Alzheimer's, Parkinson's, and depression
(Natural News) Scientists have learned a lot about most of the body’s organs over the years. The growing body of knowledge on the liver, heart, lungs and kidneys has enabled many people to enjoy much better health outcomes in recent times. However, there is still a lot about the brain that we don’t know –... (Source: NaturalNews.com)
Source: NaturalNews.com - February 19, 2019 Category: Consumer Health News Source Type: news

Intercept's drug for patients with liver fibrosis due to NASH meets main goal
Intercept Pharmaceuticals Inc said on Tuesday its treatment testing patients with liver fibrosis due to nonalcoholic steatohepatitis (NASH) met the main goal in a late-stage study. (Source: Reuters: Health)
Source: Reuters: Health - February 19, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Eat more veggies and fish - Compound in both foods found to promote heart health
(Natural News) A Polish study advises people with hypertension to eat a lot more fish and vegetables. Both types of food contain trimethylamine oxide (TMAO), a natural compound that supports the healthy functions of the heart. Trimethylamine oxide is metabolized by the liver. It is synthesized from trimethylamine, which is produced by the action of... (Source: NaturalNews.com)
Source: NaturalNews.com - February 19, 2019 Category: Consumer Health News Source Type: news

Eat more veggies and fish! Compound found in both promotes heart health
(Natural News) A Polish study advises people with hypertension to eat a lot more fish and vegetables. Both types of food contain trimethylamine oxide (TMAO), a natural compound that supports the healthy functions of the heart. Trimethylamine oxide is metabolized by the liver. It is synthesized from trimethylamine, which is produced by the action of... (Source: NaturalNews.com)
Source: NaturalNews.com - February 19, 2019 Category: Consumer Health News Source Type: news

Liver disease may increase diabetes risk in non-obese patients
Research, published inNutrition,Metabolism and Cardiovascular Diseases, suggests that non-alcoholic fatty liver disease increases diabetes risk in non-obese adults.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 18, 2019 Category: Endocrinology Source Type: news

Features of He Shou Wu-induced Liver Injury Features of He Shou Wu-induced Liver Injury
He Shou Wu, a Chinese herb used since ancient times as an anti-aging remedy and all-around health tonic, can result in severe, sometimes fatal liver injury.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 18, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Infectious Complications in Liver Failure Patients Infectious Complications in Liver Failure Patients
What are the most commonly reported infectious complications among patients with liver failure, and what are the risk factors for these infections?Seminars in Respiratory and Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 18, 2019 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

New study confirms broccoli to be extremely effective at battling liver cancer
(Natural News) Even though we’ve made tremendous advances in science in recent years, some of the best medicine you can find today comes from plants and trees. Case in point: broccoli. It’s always been considered a health food, but now, a new study published in the Journal of Nutrition shows that this cruciferous vegetable has... (Source: NaturalNews.com)
Source: NaturalNews.com - February 17, 2019 Category: Consumer Health News Source Type: news

FDA OKs Triclabendazole for Tropical Disease Fascioliasis FDA OKs Triclabendazole for Tropical Disease Fascioliasis
Fascioliasis (liver fluke infestation) is a waterborne and foodborne neglected tropical disease affecting an estimated 2.4 million people worldwide, with an additional 180 million at risk.FDA Approvals (Source: Medscape Pulmonary Medicine Headlines)
Source: Medscape Pulmonary Medicine Headlines - February 16, 2019 Category: Respiratory Medicine Tags: Infectious Diseases News Alert Source Type: news

Trial launched to study HIV-to-HIV liver transplant outcomes
The country's first large-scale clinical trial to study the safety of liver transplants between people with HIV was launched on Thursday. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 15, 2019 Category: Consumer Health News Source Type: news

Uganda: Government Opens Cancer Centre in Arua
[Monitor] Arua -Ms Neria Driwaru, 70, a resident of Awupi Village in Ayivuni Sub-county in Arua District, has since 2015 been living with cancer of the liver. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 15, 2019 Category: African Health Source Type: news

GI Dynamics ’ 2nd Chance at an EndoBarrier Pivotal Trial
GI Dynamics’ fortunes might be changing, as the embattled device maker has crossed the last hurdle in its bid for the approval of a new pivotal trial to evaluate its obesity and diabetes treatment device, the EndoBarrier. The company recently announced it had received Institutional Review Board approval to launch a pivotal trial of the EndoBarrier. GI Dynamics has struggled significantly with the device in the past (more on that later), but until recently it has had some success. In August of 2018, FDA gave a nod to the EndoBarrier’s pivotal trial. The last step was for the firm to secur...
Source: MDDI - February 14, 2019 Category: Medical Devices Authors: Omar Ford Tags: Regulatory and Compliance Source Type: news

NIH clinical trial to track outcomes of liver transplantation from HIV-positive donors to HIV-positive recipients
Study follows passage of HOPE Act of 2013, allowing people with HIV to become organ donors. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - February 14, 2019 Category: American Health Source Type: news

Hepatic and Renal Toxicity in HIV-Infected Children on ART Hepatic and Renal Toxicity in HIV-Infected Children on ART
How prevalent are liver abnormalities and kidney dysfunction among HIV-infected children receiving ART? Which factors may be associated with these adverse events?HIV Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 14, 2019 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news

NIH trial to track outcomes of liver transplantation from HIV+ donors to HIV+ recipients
(NIH/National Institute of Allergy and Infectious Diseases) The first large-scale clinical trial studying liver transplantation between people with HIV has begun at clinical centers across the US. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery. The study is sponsored by the National Institute of Allergy and Infectious Diseases and follows the 2018 launch of a similar study evaluating kidney transplantation between people with HIV. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 14, 2019 Category: Infectious Diseases Source Type: news

Platinum nanoparticles for selective treatment of liver cancer cells
(ETH Zurich) Researchers at ETH Zurich recently demonstrated that platinum nanoparticles can be used to kill liver cancer cells with greater selectivity than existing cancer drugs. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 14, 2019 Category: Cancer & Oncology Source Type: news

HCV Eradication Tied to Lower Risks of Premature Death and Liver Cancer (CME/CE)
(MedPage Today) -- " Best evidence to date " backs direct-acting antivirals in all hepatitis C patients (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - February 13, 2019 Category: Gastroenterology Source Type: news

Newer HCV Drugs Reduce Mortality, Liver Cancer Risk Newer HCV Drugs Reduce Mortality, Liver Cancer Risk
Treatment with direct-acting antivirals appears to reduce the risk of death and liver cancer among patients with chronic hepatitis C virus (HCV), including those with cirrhosis, new data has shown.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 13, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Improved Outcomes Seen With Liver Grafts From Older Donors
WEDNESDAY, Feb. 13, 2019 -- From 2003 to 2016, liver graft loss and mortality improved among recipients of liver grafts from older donors, according to a study published online Feb. 13 in JAMA Surgery. Christine E. Haugen, M.D., from the Johns... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 13, 2019 Category: Pharmaceuticals Source Type: news

Gilead Misses Key Goal in NASH Liver Disease Trial, Shares Sink Gilead Misses Key Goal in NASH Liver Disease Trial, Shares Sink
Gilead Sciences Inc said on Monday that a late-stage study of a key experimental drug aimed at treating NASH, a progressive fatty liver disease, failed to meet its main goal, sending the company's shares down 4.6 percent in after-hours trading.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 13, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Even chicken, turkey and lean steak can cause fatty liver disease
A study by the Erasmus MC University Medical Centre in Rotterdam found people who rely on vegetables as their main source of protein are less at risk even if they eat more calories. (Source: the Mail online | Health)
Source: the Mail online | Health - February 13, 2019 Category: Consumer Health News Source Type: news

Sausages, bacon and steak cause fatty liver disease
A study by the Erasmus MC University Medical Centre in Rotterdam found people who rely on vegetables as their main source of protein are less at risk even if they eat more calories. (Source: the Mail online | Health)
Source: the Mail online | Health - February 13, 2019 Category: Consumer Health News Source Type: news

Nurse, 27, gets life-saving liver transplant after waiting FOUR YEARS
Olivia Price, from Wolverhampton, was diagnosed with liver disease aged 10-weeks. Initial surgery was successful, but she needed a full transplant in March 2014. (Source: the Mail online | Health)
Source: the Mail online | Health - February 13, 2019 Category: Consumer Health News Source Type: news