Insights & Outcomes: Transplant access, atmospheric rivers, and mind states
Yale researchers hunt for old atmospheric rivers, analyze access to liver transplants, and look at key proteins in Parkinson ’s disease and the nuclear envelope. (Source: Yale Science and Health News)
Source: Yale Science and Health News - December 5, 2023 Category: Universities & Medical Training Source Type: news

STAT3 palmitoylation initiates a positive feedback loop that promotes the malignancy of hepatocellular carcinoma cells in mice | Science Signaling
Liver tumor growth in mice is exacerbated by a feed-forward loop triggered by the palmitoylation of STAT3. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - December 5, 2023 Category: Science Source Type: news

89bio Outlines Roadmap For Pivotal Studies For Lead Program In Fatty Liver Disease
89bio Inc ETNB announced a successful end-of-Phase 2 Meeting with the FDA supporting the advancement of pegozafermin into Phase 3 in nonalcoholic steatohepatitis (NASH). The program will include two Phase 3 trials evaluating patients with NASH: • ENLIGHTEN-Cirrhosis trial will enroll patients with…#incetnb #fda #phase3 #enlightencirrhosis #f2f3 #ema #enlightenfibrosis #glp1 (Source: Reuters: Health)
Source: Reuters: Health - December 4, 2023 Category: Consumer Health News Source Type: news

Roche enters into a definitive merger agreement to acquire Carmot Therapeutics, including three clinical stage assets with best-in-class potential in obesity and diabetes
Carmot Therapeutics ’s R&D portfolio of clinical stage incretins has great potential to treat obesity, diabetes and potentially other diseases both as standalone medicines and in combination with Roche ’s in-house assetsLead asset CT-388 is a Phase-2 ready dual GLP-1/GIP agonist with best-in-class potential for the treatment of obesity and its comorbiditiesUnder the terms of the agreement, Roche will pay a purchase price of USD 2.7 billion upfront and additional milestone payments of up to USD 400 millionBasel, 4 December 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the entry into a definitive merger a...
Source: Roche Investor Update - December 4, 2023 Category: Pharmaceuticals Source Type: news

Roche enters into a definitive merger agreement to acquire Carmot Therapeutics, including three clinical stage assets with best-in-class potential in obesity and diabetes
Carmot Therapeutics ’s R&D portfolio of clinical stage incretins has great potential to treat obesity, diabetes and potentially other diseases both as standalone medicines and in combination with Roche ’s in-house assetsLead asset CT-388 is a Phase-2 ready dual GLP-1/GIP agonist with best-in-class potential for the treatment of obesity and its comorbiditiesUnder the terms of the agreement, Roche will pay a purchase price of USD 2.7 billion upfront and additional milestone payments of up to USD 400 millionBasel, 4 December 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the entry into a definitive merger a...
Source: Roche Media News - December 4, 2023 Category: Pharmaceuticals Source Type: news

Tool Identifies Alcohol Relapse Risk After Liver Transplant Tool Identifies Alcohol Relapse Risk After Liver Transplant
A novel prognostic tool based on social determinants effectively predicted increased risk of alcohol use relapse in adults who underwent liver transplants for alcoholic liver disease.MDedge News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - December 1, 2023 Category: Transplant Surgery Tags: Gastroenterology News Source Type: news

New CT, MR scanners and AI top GE HealthCare highlights at RSNA 2023
CHICAGO -- GE HealthCare (GEHC) brought new CT and MRI scanners and a range of AI software applications to McCormick Place for RSNA 2023. CT In CT, GEHC shined the spotlight on its Revolution Ascend scanner, which was first introduced at ECR in March. With onsite detector upgrades, Ascend can be upgraded from a 20-mm coverage system for routine scanning to a 40-mm coverage system that delivers better low-contrast detectability, according to the vendor. The scanner also comes with True Enhance DL, an AI-based application that generates deep learning-based monochromatic-like images from a single-energy x-ray acquisition....
Source: AuntMinnie.com Headlines - December 1, 2023 Category: Radiology Authors: Erik L. Ridley Tags: RSNA 2023 Source Type: news

Orcas killed a great white shark for its liver in Australia, scientists confirmed, leaving the sharks one less place to hide
None A great white shark washed up on a beach in Australia completely disemboweled. • None Scientists confirmed that it was killed by orcas, who hunted the great white for its liver. • None The proof was in bite marks on the shark's body that were "just loaded with killer whale DNA." In October,…#nonescientists #victoria #adammiller #deakinuniversity #abcradiomelbourne #southafrica #mosselbay #makosharks #livescience #bay (Source: Reuters: Health)
Source: Reuters: Health - December 1, 2023 Category: Consumer Health News Source Type: news

A New mRNA Malaria Vaccine 
By targeting resident memory T cells in the liver, a novel mRNA malaria vaccine prevented infection, even in those with prior exposure. (Source: The Scientist)
Source: The Scientist - November 30, 2023 Category: Science Tags: News News & Opinion Source Type: news

Video from RSNA: Researcher talks CEUS study with AuntMinnie.com
Contrast-enhanced ultrasound (CEUS) can differentiate between liver lesions, according to research presented November 26 at the 2023 RSNA annual meeting. Jordan Swensson, MD, from Indiana University talked about the study he and his team led to AuntMinnie.com, as well as why there should be more optimization for CEUS. (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 30, 2023 Category: Radiology Authors: Amerigo Allegretto Tags: Ultrasound RSNA 2023 Source Type: news

Polaris Group Announces First Patient Successfully Dosed with ADI-PEG 20/Placebo in Phase 2a Non-Alcoholic Steatohepatitis (NASH) Study
TAIPEI, Taiwan and SAN DIEGO, Nov. 29, 2023 (GLOBE NEWSWIRE) -- Polaris Group (The Company, TWSE:6550), today announced that the first patient was successfully dosed in the Phase 2a clinical study for Non-Alcoholic Steatohepatitis (NASH). NASH, a progressive liver disease closely associated with…#taipei #taiwan #sandiego #polarisgroup #nash #adipeg20 #adipeg #howardchen #pegargiminase #bla (Source: Reuters: Health)
Source: Reuters: Health - November 30, 2023 Category: Consumer Health News Source Type: news

Development and mechanical analysis of human liver model during impact - Du T, Chen J, Li D, Liu X, Hu Y.
Liver injury is one of the most severe traffic trauma. The development of accurate liver finite element model is beneficial for improving the biofidelity and validity in crash simulations, aiming to analyze the injury in accidents. 12 human liver finite el... (Source: SafetyLit)
Source: SafetyLit - November 28, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

What are the benefits of using an AI server downstream of PACS?
CHICAGO -- Among the imaging informatics sessions at RSNA 2023 are innovations designed to reduce the barriers of running AI algorithms in everyday radiology. To that end, research at the University of Pennsylvania suggests starting with an AI server. “For radiologists, we need AI to be fast … unobtrusive … and verifiable. We want AI results ready by the time we open a study,” explained presenter Neil Chatterjee, MD, PhD. “From the IT or enterprise point of view, we want AI that is secure,” he said, emphasizing fast outputs, smooth integration, and adhering to standards such as DICOM and HL7.Neil Chatterjee, MD...
Source: AuntMinnie.com Headlines - November 28, 2023 Category: Radiology Authors: Liz Carey Tags: Enterprise Imaging PACS/VNA RSNA 2023 Source Type: news

EXCLUSIVE: Ill, thin and broken, ex-England footballer Kieron Dyer, 44, was dying with a rare liver disease just 11 weeks ago. Now, he speaks for the first time after a 'miracle' transplant gave him a second shot at life
OLIVER HOLT: Kieron Dyer's version of A Christmas Carol has seen him get a second shot at life alongside wife, Holly, following a life-saving liver transplant. (Source: the Mail online | Health)
Source: the Mail online | Health - November 27, 2023 Category: Consumer Health News Source Type: news