Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (R01 Clinical Trial Not Allowed)
The goal of this Funding Opportunity Announcement (FOA) is to support translational research that provides strong justification for later-phase therapeutics discovery and development efforts in health-related outcomes relevant to the National Institute of Diabetes and Digestive and Kidney Diseases. This includes outcomes relevant to obesity, diabetes and related aspects of endocrinology and metabolism, digestive diseases, liver diseases, nutrition, kidney and urological diseases, and hematology. Additional information concerning programmatic areas at NIDDK is available a www.niddk.nih.gov/research-funding/research-programs...
Source: NIDDK Funding Opportunities - June 6, 2019 Category: Endocrinology Source Type: funding

Immunobiology of Xenotransplantation (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-19-042 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications from institutions to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), for the development of preclinical porcine-to-nonhuman primate (NHP) models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. The goals of this program are to: (1) delineate the cellular and molecular mechanisms of xenograft rejection and/or the induction of immune tolerance; (2) develop effective strategies to improve xenograft survival; and (...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 30, 2019 Category: Research Source Type: funding

Immunobiology of Xenotransplantation (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-19-043 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications from institutions to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), for the development of preclinical porcine-to-nonhuman primate (NHP) models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. The goals of this program are to: (1) delineate the cellular and molecular mechanisms of xenograft rejection and/or the induction of immune tolerance; (2) develop effective strategies to improve xenograft survival; and (...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 30, 2019 Category: Research Source Type: funding

Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)
Funding Opportunity RFA-DK-19-004 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases. DDRCCs are based on the core concept, whereby shared resources aimed at...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 13, 2019 Category: Research Source Type: funding

Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investig...
Source: NIDDK Funding Opportunities - March 13, 2019 Category: Endocrinology Source Type: funding

Notice of Correction to Cover Instructions for RFA-DK-18-501 Limited Competition for the Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Clinical Centers (U01 Clinical Trial Required)
Notice NOT-DK-19-006 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 19, 2018 Category: Research Source Type: funding

Limited Competition for the Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Clinical Centers (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-18-501 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN is composed of a Scientific and Data Coordination Center (SDCC) and Clinical Centers (CC). ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progressive Familial Intrahepatic Cholestasis syndromes;...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 18, 2018 Category: Research Source Type: funding

Limited Competition for the Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Scientific and Data Coordinating Center (U24 Clinical Trial Optional)
Funding Opportunity RFA-DK-18-502 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN will be composed of a Scientific and Data Coordination Center (DCC), Clinical Centers (CC) , and the NIDDK/NIH as the sponsor of the Network. ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 18, 2018 Category: Research Source Type: funding

Limited Competition for the Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Scientific and Data Coordinating Center (U24 Clinical Trial Optional)
The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN will be composed of a Scientific and Data Coordination Center (DCC), Clinical Centers (CC) , and the NIDDK/NIH as the sponsor of the Network. ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progressive Familial Intrahepatic Cholestasis syndromes; Bile acid synthesis defects; M...
Source: NIDDK Funding Opportunities - September 18, 2018 Category: Endocrinology Source Type: funding

Limited Competition for the Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Clinical Centers (U01 Clinical Trial Required)
The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN is composed of a Scientific and Data Coordination Center (SDCC) and Clinical Centers (CC). ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progressive Familial Intrahepatic Cholestasis syndromes; Bile acid synthesis defects; Mitochondrial hepatopathies; Idiopathic Neonatal Hep...
Source: NIDDK Funding Opportunities - September 18, 2018 Category: Endocrinology Source Type: funding

Limited Competition for the Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Centers (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-18-505 from the NIH Guide for Grants and Contracts. The purpose of this limited competition funding opportunity announcement (FOA) is to continue the support of the Clinical Sites of the NASH Clinical Research Network (NASH CRN) as they complete active clinical treatment trials and continue to longitudinally gather biospecimens and data of children and adults with nonalcoholic fatty liver disease (NAFLD), including steatosis, steatohepatitis, and cirrhosis (NAFLD database study). The NASH CRN has been sponsored by the NIDDK since 2002, and renewed in 2009 and 2014. Research in the NASH CRN has...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 24, 2018 Category: Research Source Type: funding

Limited Competition for the Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Data Coordinating Center (U24 Clinical Trial Required)
Funding Opportunity RFA-DK-18-506 from the NIH Guide for Grants and Contracts. The purpose of this limited competition funding opportunity announcement (FOA) is to continue the support of the Data Coordinating Center of the NASH Clinical Research Network (NASH CRN) as they complete active clinical treatment trials and continue to longitudinally gather biospecimens and data of children and adults with nonalcoholic fatty liver disease (NAFLD), including steatosis, steatohepatitis, and cirrhosis (NAFLD database study). The NASH CRN has been sponsored by the NIDDK since 2002, and renewed in 2009 and 2014. Research in the NA...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 24, 2018 Category: Research Source Type: funding

Limited Competition for the Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Centers (U01 Clinical Trial Required)
The purpose of this limited competition funding opportunity announcement (FOA) is to continue the support of the Clinical Sites of the NASH Clinical Research Network (NASH CRN) as they complete active clinical treatment trials and continue to longitudinally gather biospecimens and data of children and adults with nonalcoholic fatty liver disease (NAFLD), including steatosis, steatohepatitis, and cirrhosis (NAFLD database study). The NASH CRN has been sponsored by the NIDDK since 2002, and renewed in 2009 and 2014. Research in the NASH CRN has been focused on the etiology, contributing factors, natural history, complication...
Source: NIDDK Funding Opportunities - August 24, 2018 Category: Endocrinology Source Type: funding

Limited Competition for the Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Data Coordinating Center (U24 Clinical Trial Required)
The purpose of this limited competition funding opportunity announcement (FOA) is to continue the support of the Data Coordinating Center of the NASH Clinical Research Network (NASH CRN) as they complete active clinical treatment trials and continue to longitudinally gather biospecimens and data of children and adults with nonalcoholic fatty liver disease (NAFLD), including steatosis, steatohepatitis, and cirrhosis (NAFLD database study). The NASH CRN has been sponsored by the NIDDK since 2002, and renewed in 2009 and 2014. Research in the NASH CRN has been focused on the etiology, contributing factors, natural history, co...
Source: NIDDK Funding Opportunities - August 24, 2018 Category: Endocrinology Source Type: funding