Interfering with Interferons for Host Targeted Therapy of Bacterial Infections.
Laurel Lenz has made major contributions to our understanding of the innate and adaptive immune response to the intracellular bacterial pathogen Listeria monocytogenes. As a Ph.D. student with Mike Bevan at the University of Washington Laurel performed pioneering work on the requirements for CD8+ antigen presentation by Listeria identifying a role for the non-classical restriction element H-2-M3. Later as a postdoctoral fellow in the lab of Dan Portnoy at UC Berkeley he delved into the cell biology of the Listeria-macrophage interaction discovering a new secretory element SecA2 that influences both virulence and the induct...
Source: Videocast - All Events - September 28, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

2010-2015: Cancer Immunotherapy's Inflection Point
NCI’s Center for Cancer Research (CCR) Grand RoundsDr. Pardoll is an Abeloff Professor of Oncology,Medicine, Pathology and Molecular Biology and Genetics at the Johns HopkinsUniversity, School of Medicine.  He isDirector of the Cancer Immunology in the Sidney Kimmel Comprehensive CancerCenter.  Dr. Pardoll attended JohnsHopkins University, where he earned his M.D., Ph.D., in 1982 and completed hisMedical Residency and Oncology Fellowship in 1985. He then worked for threeyears at the National Institutes of Health as a Medical Staff Fellow.  Dr. Pardoll joined the departments ofoncology and medicine in 1...
Source: Videocast - All Events - September 28, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video