A Genetic Test Could Help Predict the Right Antidepressant For You
Depression is a complicated condition, and so are the people it affects. It’s often difficult — and can take months or even years — to find the right drugs to treat the heterogeneous mood disorder.
But for decades, doctors have been treating depression essentially by prescribing a drug and hoping for the best. They rely on asking people about their family history of mental illness and fold in as much information as they can about symptoms. Since 2010, however, there has been a genetic test that can help doctors learn how a person’s genetic makeup can also affect their response to various antidepress...
Source: TIME: Health - May 7, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Brain Depression healthy time Source Type: news
Soterix touts transcranial stim depression trial results
Soterix Medical today released results from trials of its direct current stimulation-limited total energy technology designed to treat depression, touting that the device was found to be safe and effective with improvements in depression-rating metrics lasting for a month after treatment.
The tDCS-LTE system is designed to deliver energy to the dorsolateral prefrontal cortex region of the brain which is implicated in depression control, the New York-based company said.
In the first trial, the company reported that its tDCS-LTE system was effective and safe as an add-on intervention for patients with type I or II bipolar di...
Source: Mass Device - April 11, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Neurological Neuromodulation/Neurostimulation Soterix Medical Source Type: news
Study: PET imaging agent could help predict depression drug ’ s efficacy
Image courtesy of Mala Ananth
Researchers have identified a positron emission tomography imaging agent that could identify the patients that are more likely to benefit from a drug designed to treat major depressive disorder, according to a study published this month in The Journal of Nuclear Medicine.
The C-DASB tracer targets a protein, 5-HTT, found in the part of a person’s brain that is responsible for emotional processing, called the amygdala. Escitalopram, a selective serotonin reuptake inhibitor, is indicated for people with depression, but it doesn’t work for all patients. Scanning a person’s brain to measure...
Source: Mass Device - April 6, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Imaging Neurological Pharmaceuticals Research & Development National Institutes of Health (NIH) Source Type: news
Lexapro vs. Cymbalta
Title: Lexapro vs. CymbaltaCategory: MedicationsCreated: 2/26/2018 12:00:00 AMLast Editorial Review: 2/26/2018 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - February 26, 2018 Category: Psychiatry Source Type: news
Lexapro vs. Paxil
Title: Lexapro vs. PaxilCategory: MedicationsCreated: 2/26/2018 12:00:00 AMLast Editorial Review: 2/26/2018 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - February 26, 2018 Category: Psychiatry Source Type: news
21 Reviewed Antidepressants Top Placebo for Major Depression
Agomelatine, amitriptyline, escitalopram are among most effective agents in head - to - head trials (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - February 22, 2018 Category: Psychiatry Tags: Family Medicine, Gynecology, Internal Medicine, Pharmacy, Psychiatry, Journal, Source Type: news
These Antidepressants Are Most Effective, Study Says
Millions of people take antidepressants for depression. But there’s long been debate over just how effective the medications actually are. On Wednesday, a large new study provides evidence that antidepressants are more effective than placebo at treating acute depression in adults.
The study, published in the journal The Lancet, looked at the published data from 522 randomized controlled trials testing 21 different types of antidepressants. The study authors also reached out to pharmaceutical companies and study authors for additional unpublished study data. All told, the data collection included 116,477 men and women...
Source: TIME: Health - February 21, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news
Lexapro vs. Xanax
Title: Lexapro vs. XanaxCategory: MedicationsCreated: 2/21/2018 12:00:00 AMLast Editorial Review: 2/21/2018 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - February 21, 2018 Category: Psychiatry Source Type: news
Lexapro vs. Ativan
Title: Lexapro vs. AtivanCategory: MedicationsCreated: 2/21/2018 12:00:00 AMLast Editorial Review: 2/21/2018 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - February 21, 2018 Category: Psychiatry Source Type: news
Genotyping May Boost Antidepressant Treatment Success Genotyping May Boost Antidepressant Treatment Success
Impairments in the gene that encodes the enzyme responsible for metabolizing the antidepressant escitalopram may be responsible for treatment failure.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 19, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news
Genetic analysis can improve depression therapy
(Karolinska Institutet) The failure of SSRI antidepressants can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients, according to a new study from Karolinska Institutet in Sweden and Diakonhjemmet Hospital in Norway published in The American Journal of Psychiatry. Prescribing the dose of escitalopram based on a patient's specific genetic constitution would greatly improve therapeutic outcomes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 12, 2018 Category: International Medicine & Public Health Source Type: news
Celexa vs. Lexapro
Title: Celexa vs. LexaproCategory: MedicationsCreated: 12/18/2017 12:00:00 AMLast Editorial Review: 12/18/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - December 18, 2017 Category: Drugs & Pharmacology Source Type: news
Lexapro vs. Wellbutrin: Differences between Side Effects and Uses
Title: Lexapro vs. Wellbutrin: Differences between Side Effects and UsesCategory: MedicationsCreated: 11/2/2017 12:00:00 AMLast Editorial Review: 11/2/2017 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - November 2, 2017 Category: Psychiatry Source Type: news
Zoloft vs. Lexapro
Title: Zoloft vs. LexaproCategory: MedicationsCreated: 11/2/2017 12:00:00 AMLast Editorial Review: 11/2/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - November 2, 2017 Category: Drugs & Pharmacology Source Type: news
Lexapro vs. Effexor
Title: Lexapro vs. EffexorCategory: MedicationsCreated: 10/30/2017 12:00:00 AMLast Editorial Review: 10/30/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - October 30, 2017 Category: Drugs & Pharmacology Source Type: news
