Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism
Condition:   Subclinical Hypothyroidism Interventions:   Drug: Levothyroxine;   Other: Placebo Sponsor:   Central Arkansas Veterans Healthcare System Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 2, 2020 Category: Research Source Type: clinical trials

Evaluation of evening versus morning levothyroxine intake in elderly (MONIALE)
DiscussionConsidering the aging population, the increased prevalence of multimorbidity and polypharmacy, as well as potential drug interactions and treatment adherence difficulties, an alternative LT4 protocol could be useful for hypothyroidism treatment in the elderly. Prior studies comparing alternative LT4 administration protocols have mainly included young adult populations and have not addressed potential drug interactions.Trial registrationClinicalTrials.gov,NCT03614988. Registered 30 July 2018. (Source: Trials)
Source: Trials - December 16, 2019 Category: Research Source Type: clinical trials

Can Levothyroxine Treatment Reduce the Development of Cardio-metabolic Disorder in Subclinical Hypothyroidism?
Condition:   Subclinical hypothyroïdism and Metabolic Affection Intervention:   Drug: Levothyroxine Sponsor:   Ain Shams University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 26, 2019 Category: Research Source Type: clinical trials