Alpha-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion
To summarize, the treatment of hypertension is a critical aspect of healthcare due to its significant impact on cardiovascular health.
While natural supplements and lifestyle modifications are important for overall well-being, the use of chemical drugs in managing hypertension remains necessary.
Chemical drugs for hypertension have undergone extensive research and have been proven effective in lowering blood pressure levels.
Alpha-blockers offer a targeted approach to address the specific mechanisms involved in hypertension, allowing for precise blood pressure control.
They work by inhibiting the ...
Source: The EMT Spot - July 17, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Pathways in pathogenesis of PAH – Cardiology MCQ – Answer
Pathways in pathogenesis of PAH – Cardiology MCQ – Answer
Which of the following is NOT a pathway involved in the pathogenesis of pulmonary arterial hypertension (PAH)?
Correct answer: 4. Pentose phosphate pathway
All the other three are important pathways in the pathogenesis of PAH. Medications used in the treatment block these pathways.
Endothelin pathway blockers: Bosentan, Ambrisentan, Macitentan
Nitric oxide pathway: Sildenafil, Tadalafil, Vardenafil
Prostacyclin pathway: Epoprostenol, Iloprost, Treprostinil, Beraprost (Prostacyclin analogues) and Selexipag (Selective IP receptor antagonist). IP receptor is ...
Source: Cardiophile MD - June 10, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
The Future of Work Part I
Have you ever taken some time to think about what work will look like 5, 10 or even 20 years from now? If you haven’t, it is probably worth the effort because a changing work environment may have dramatic implications for how you are employed in the future. In these two posts, I want to talk about some of the trends I’m seeing and how they may play out in the coming years.
Outsourcing
Companies are getting better and better at spinning off specific business functions and letting them be handled by others. For example, many businesses can’t justify running payroll in-house. It is cheaper to hire a company...
Source: Productivity501 - September 20, 2016 Category: Psychiatry & Psychology Authors: Mark Shead Tags: Misc Source Type: blogs
Do hospitals need a formal appearance policy?
One day into our medical center’s newly announced colleague appearance policy, nobody has yet approached my office with a steel wool soap pad to make any of the docs or medical assistants shine. My active white coat went into the laundry bin the day before, having inserted my left sleeve into a puddle of spilled coffee. The other two lab coats with hospital logo remain in their plastic protective coating, suitable for asphyxia if your face gets too close, where they have languished on a wire hanger for months following their last encounter with laundry detergent.
There is some legitimately divided opinion on whether doct...
Source: Kevin, M.D. - Medical Weblog - June 28, 2016 Category: Journals (General) Authors: Richard M. Plotzker, MD Tags: Physician Hospital Source Type: blogs
Rising Cost Of Drugs: Where Do We Go From Here?
The trends are clear: patients and institutions across the nation are concerned about skyrocketing drug prices. This post offers some information about drug pricing, explores the notion of market intervention, and proposes a series of responses to high pharmaceutical costs.
A few jaw-dropping facts quickly illustrate the pattern of rising drug costs. The average annual cost of cancer drugs increased from roughly $10,000 before 2000 to over $100,000 by 2012, according to a recent study in Mayo Clinic Proceedings. Several breakthrough specialty medications and orphan drugs recently approved by the Food and Drug Administratio...
Source: Health Affairs Blog - August 31, 2015 Category: Health Management Authors: Ifrad Islam Tags: Costs and Spending Drugs and Medical Technology Featured Medicaid and CHIP Payment Policy Public Health Big Pharma CMS FDA Gilead Sciences hepatitis C Pricewaterhouse Coopers Source Type: blogs
The Single Senior STD Epidemic
If you think your retired parents who have settled into a low-key retirement home or senior living community are spending their time playing checkers and watching soaps, think again! They may be running around having sex just like college kids let loose in a dorm for the first time. Senior citizens, contrary to popular belief, are often still sexually active. And they are spreading sexually transmitted diseases (STDs).
According to the Center for Disease Control, since 2007, the incidence of syphilis among seniors, those 65 and over, is up by 52 percent, and the number of chlamydia cases has risen 32 percent. The rapid inc...
Source: Disruptive Women in Health Care - April 27, 2015 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Aging Source Type: blogs
Who needs Viagra?
Yes, erectile dysfunction can reverse with the Wheat Belly lifestyle. But why and how?
Erectile dysfunction, ED, and thereby erections, are fairly complicated phenomena. But the capacity to mount an erection parallels arterial health elsewhere in the body, particularly in the heart, since penile erections are a blood flow regulation phenomenon. In my cardiology practice, for instance, it was virtually the rule to see ED coupled with coronary disease, since coronary disease is essentially an expression of poor arterial function and health, also. If you have coronary disease, you likely have ED; if you have ED, you likely ha...
Source: Wheat Belly Blog - February 21, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle erectile dysfunction fish oil grains omega-3 sex sexual vitamin D Source Type: blogs
Study Suggests Link Between Viagra And Melanoma
In recent years researchers have uncovered a potentially important pathway whereby PDE5A inhibitors (which include sildenafil– Viagra– and other drugs used to treat erectile dysfunction and pulmonary hypertension) could potentially increase the risk of developing melanoma. Now a new study provides early evidence showing an association between sildenafil and melanoma, though, like all observational studies, it is unable to demonstrate a cause-and-effect relationship. … Click here to read the full post on Forbes. (Source: CardioBrief)
Source: CardioBrief - April 8, 2014 Category: Cardiology Authors: Larry Husten Tags: Prevention, Epidemiology & Outcomes Cialis erectile dysfunction Levitra melanoma PDE5A inhibitors Viagra Source Type: blogs
The Discrediting OTC Ads – Articles Include Potentially Misleading Claims
The objective of the study was to compare claims in direct-to-consumer (DTC) television advertising with the FDA approved labeling in order to evaluate the frequency of false or misleading ads.
The United States is one of the only countries in the world that allows drug companies to directly advertised to patients or consumers through basically any medium—television, magazine, newspaper, etc. However, we recently reported that advertisements online and through social media have been a difficult and uncertain area for companies to advertise due to the lack of guidance and clarity from FDA on the issue.
To conduct the ...
Source: Policy and Medicine - December 27, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs
Bayer in hot water over nightcaps and pick me ups!
Stories:
http://www.pharmafile.com/news/181130/bayer-slammed-nightcaps
http://www.pharmafile.com/news/101105/bayer-abpi-audit-shocking-levitra-error (Source: PharmaGossip)
Source: PharmaGossip - September 27, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs
FDA shuts down 1,677 online pharmacies
The prices may look tempting, but ordering from an online pharmacy is often a bad deal, according to Interpol and the U.S Food and Drug Administration, announcing a crackdown Thursday on thousands of websites.The FDA said it has shut down 1,677 sites for selling counterfeit or substandard medication, or for selling drugs without appropriate safeguards. Other sites received regulatory warnings. Officials said they also arrested 58 people and seized more than $41 million worth of illegal medicines.Several sites had sleek interfaces and names that could easily be confused with legitimate pharmacy retailers. For example, the F...
Source: PharmaGossip - June 27, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs
Lybrido for Low Libido?
A feature article in last week's New York Times Magazine served as an extended ad for a new book by Daniel Bergner, What Do Women Want? Adventures in the Science of Female Desire. It's filled with post-fashionable pop neuroscience and simplistic neurotransmitter stereotypes that rival those of Naomi Wolf (including her infamous “dopamine is the ultimate feminist chemical in the female brain” quote). The focus of Bergner’s article is on pharmaceutical treatments for the controversial diagnosis of Hypoactive Sexual Desire Disorder (HSDD), particularly the subtly named Lybrido (along with its younger sister, Lybri...
Source: The Neurocritic - June 3, 2013 Category: Psychiatrists and Psychologists Authors: The Neurocritic Source Type: blogs
Sex, Lies & DTC Advertising For Impotence Pills
Several years ago, the drugmakers that sell impotence pills convinced Congress that federal regulations were not required to ensure objectionable ads would not be seen by children. However, a new study charges that industry efforts to regulate direct-to-consumer advertising have been a “ruse” designed to deflect criticism and block Congress from intervening.
From 2006 to 2010, when DTC advertising for erectile dysfunction pills rose 62 percent, to $324.3 million, the study found a “consistent pattern” in which drugmakers failed to comply with so-called guiding principles that were propagated by the ...
Source: Pharmalot - February 20, 2013 Category: Pharma Commentators Authors: Ed Silverman Tags: Uncategorized Bayer Cialis Eli Lilly Erectile Dysfunction GlaxoSmithKline Impotence Leviitra Merck Pfizer Viagra Source Type: blogs
Pharma "failing to self-police DTC ads"
via pharmatimes.com The pharmaceutical industry's efforts to self-regulate its direct-to-consumer (DTC) advertising are "an industry-sponsored ruse" intended to deflect criticism and collectively block new US federal regulation, a new study claims. Reporting in the Journal of Health Politics, Policy and Law, the researchers studied the US marketing campaigns for three erectile dysfunction (ED) drugs - Pfizer's Viagra (sildenafil citrate), Eli Lilly's Cialis (tadalafil) and Bayer HealthCare's Levitra (vardenafil), marketed in the US by Bayer Healthcare, GlaxoSmithKline and Merck & Co - from 2006 to 2010. All these companies...
Source: PharmaGossip - February 20, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs
ED Drug Advertisers "Cockblocked" PhRMA's DTC Guiding Principle #13
The pharmaceutical industry's efforts to self-regulate its direct-to-consumer (DTC) advertising are "an industry-sponsored ruse," intended to deflect criticism and collectively block new Federal regulation, a study released today in the Journal of Health Politics, Policy and Law found. The paper, "The Politics and Strategy of Industry Self-Regulation: The Pharmaceutical Industry's Principles for Ethical Direct-to-Consumer Advertising as a Deceptive Blocking Strategy," which you can find here, was written by Denis Arnold, Associate Professor of Management and Surtman Distinguished Scholar in Business Ethics in the Belk Coll...
Source: Pharma Marketing Blog - February 16, 2013 Category: Pharma Commentators Tags: PhRMA Guidelines PhRMA Intern Erectile Dysfunction Cialis Viagra DTC Advertising Levitra Source Type: blogs
