A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions
Conditions: Leiomyosarcoma; Soft-tissue Sarcomas Interventions: Drug: Gemcitabine; Drug: Nab-Sirolimus Sponsors: M.D. Anderson Cancer Center; Aadi Bioscience Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
NM32-2668 in Adult Patients With Selected Advanced Solid Tumors
Conditions: Ovarian Carcinoma; Fallopian Tube Carcinoma; Peritoneal Carcinoma; Endometrial Cancer; Adenocarcinoma of Lung; Triple Negative Breast Cancer; Liposarcoma; Leiomyosarcoma; Mesothelioma, Malignant; Adenocarcinoma - Gastroesophageal Junction (GEJ); Adenocarcinoma of the Stomach; Melanoma, Malignant; Renal Cell Carcinoma Interventions: Biological: NM32-2668 Sponsors: Numab Therapeutics AG Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma
Conditions: Leiomyosarcoma; Liposarcoma; Synovial Sarcoma; Angiosarcoma; Undifferentiated Pleomorphic Sarcoma; Epithelioid Sarcoma; Malignant Peripheral Nerve Sheath Tumors; Fibrosarcoma; Pleomorphic Rhabdomyosarcoma; Endometrial Stromal Sarcoma; Desmoplastic Small Round Cell Tumor Interventions: Biological: MASCT-I; Drug: Doxorubicin; Drug: Ifosfamide Sponsors: HRYZ Biotech Co. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids
Conditions: Uterine Fibroid; Uterine Sarcoma; Uterine Leiomyosarcoma Interventions: Procedure: TU-LESS; Procedure: MPLS Sponsors: West China Second University Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 6, 2024 Category: Research Source Type: clinical trials
Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy
Conditions: Muscle-Invasive Bladder Carcinoma; Muscle Invasive Bladder Urothelial Carcinoma; Bladder Cancer TNM Staging; Bladder Cancer Stage IIa; Bladder Cancer Stage IIb; Bladder Cancer Stage IV; Bladder Leiomyosarcoma; Bladder Cancer; Bladder Cancer Stage II; Bladder Cancer Stage IIIa; Bladder Cancer Stage IIIb; Bladder Cancer Stage IIIc; Bladder Urothelial Carcinoma; Progression, Disease; Urinary Diversion; Neobladder; Radical Cystectomy Interventions: Procedure: Radical Cystectomy Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma
Conditions: Leiomyosarcoma Interventions: Drug: Lurbinectedin; Drug: Doxorubicin Sponsors: PharmaMar Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 18, 2023 Category: Research Source Type: clinical trials
Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People > = 18 Years Old With Advanced Soft Tissue Sarcoma
Conditions: Metastatic Extraskeletal Myxoid Chondrosarcoma; Metastatic Leiomyosarcoma; Metastatic Liposarcoma; Metastatic Undifferentiated Pleomorphic Sarcoma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Drug: Cabozantinib; Procedure: Computed Tomography; Biological: Ipilimumab; Procedure: Magnetic Resonance Imaging; Biological: Nivolumab Sponsor: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 1, 2023 Category: Research Source Type: clinical trials
