Sensors, Vol. 24, Pages 2620: Emotion Classification Based on Pulsatile Images Extracted from Short Facial Videos via Deep Learning
This study improves an emotion classification approach developed in a previous study, which classifies emotions remotely without relying on stereotypical facial expressions or contact-based methods, using short facial video data. In this approach, we desire to remotely sense transdermal cardiovascular spatiotemporal facial patterns associated with different emotional states and analyze this data via machine learning. In this paper, we propose several improvements, which include a better remote heart rate estimation via a preliminary skin segmentation, improvement of the heartbeat peaks and troughs detection process, and ob...
Source: Sensors - April 19, 2024 Category: Biotechnology Authors: Shlomi Talala Shaul Shvimmer Rotem Simhon Michael Gilead Yitzhak Yitzhaky Tags: Article Source Type: research

Sensors, Vol. 24, Pages 2616: Structural Damage Detection Based on the Correlation of Variational Autoencoder Neural Networks Using Limited Sensors
Ma Identifying the structural state without baseline data is an important engineering problem in the field of structural health monitoring, which is crucial for assessing the safety condition of structures. In the context of limited accelerometers available, this paper proposes a correlation-based damage identification method using Variational Autoencoder neural networks. The approach involves initially constructing a Variational Autoencoder network model for bridge damage detection, optimizing parameters such as loss functions and learning rates for the model, and ultimately utilizing response data from limited senso...
Source: Sensors - April 19, 2024 Category: Biotechnology Authors: Jun Lin Hongwei Ma Tags: Article Source Type: research

Sensors, Vol. 24, Pages 2611: A Post-Processing Multipath/NLoS Bias Estimation Method Based on DBSCAN
o Dovis Positioning based on Global Navigation Satellite Systems (GNSSs) in urban environments always suffers from multipath and Non-Line-of-Sight (NLoS) effects. In such conditions, the GNSS pseudorange measurements can be affected by biases disrupting the GNSS-based applications. Many efforts have been devoted to detecting and mitigating the effects of multipath/NLoS, but the identification and classification of such events are still challenging. This research proposes a method for the post-processing estimation of pseudorange biases resulting from multipath/NLoS effects. Providing estimated pseudorange biases due to...
Source: Sensors - April 19, 2024 Category: Biotechnology Authors: Yihan Guo Simone Zocca Paolo Dabove Fabio Dovis Tags: Article Source Type: research

Recontact to return new or updated PALB2 genetic results in the clinical laboratory setting
Conclusion Novel pathogenic variants in PALB2 were identified in 18 individuals through retrospective gene panel testing. Recontacting these individuals regarding these new or updated findings had a range of outcomes. The process of conveying genomic results within this framework can be effectively accomplished while upholding patient autonomy, potentially leading to advantageous outcomes for patients and their families. (Source: Journal of Medical Genetics)
Source: Journal of Medical Genetics - April 19, 2024 Category: Genetics & Stem Cells Authors: Panchal, S., Mahajan, R., Aujla, N., McKay, P., Casalino, S., Di Gioacchino, V., Charames, G. S., Lefebvre, M., Metcalfe, K. A., Akbari, M. R., McCuaig, J. M., Lerner-Ellis, J. Tags: Cancer genetics Source Type: research

IJERPH, Vol. 21, Pages 503: Intersectional Mentorship in Academic Medicine: A Conceptual Review
owleg Academic medical institutions seek to recruit and retain a diverse workforce to foster equitable, supportive environments in which early-stage investigators, especially those who are underrepresented in medicine, can thrive. Intersectionality is a critical theoretical framework rooted in Black feminist activism and scholarship that elucidates how power and privilege are differentially structured for groups at different intersectional sociodemographic positions. As a dynamic method of analyzing multiple axes of power and inequality, intersectionality has the potential to offer a critical lens through which to view...
Source: International Journal of Environmental Research and Public Health - April 19, 2024 Category: Environmental Health Authors: Jae M. Sevelius Orlando O. Harris Lisa Bowleg Tags: Review Source Type: research

Molecules, Vol. 29, Pages 1857: Binding Mechanism of Inhibitors to BRD4 and BRD9 Decoded by Multiple Independent Molecular Dynamics Simulations and Deep Learning
hong Chen Bromodomain 4 and 9 (BRD4 and BRD9) have been regarded as important targets of drug designs in regard to the treatment of multiple diseases. In our current study, molecular dynamics (MD) simulations, deep learning (DL) and binding free energy calculations are integrated to probe the binding modes of three inhibitors (H1B, JQ1 and TVU) to BRD4 and BRD9. The MD trajectory-based DL successfully identify significant functional function domains, such as BC-loop and ZA-loop. The information from the post-processing analysis of MD simulations indicates that inhibitor binding highly influences the structural flexibil...
Source: Molecules - April 19, 2024 Category: Chemistry Authors: Jian Wang Wanchun Yang Lu Zhao Benzheng Wei Jianzhong Chen Tags: Article Source Type: research

Volumetric segmentation in the context of posterior fossa-related pathologies: a systematic review
ConclusionsVarious forms of segmentation techniques have been used to assess posterior fossa volumes/pathologies and each has its advantages and disadvantages. We discuss these nuances and summarize the current state of literature in the context of posterior fossa-associated pathologies. (Source: Neurosurgical Review)
Source: Neurosurgical Review - April 19, 2024 Category: Neurosurgery Source Type: research

Prediction of mass spectrometry ionization efficiency based on COSMO-RS and machine learning algorithms
Analyst, 2024, Advance Article DOI: 10.1039/D4AN00301B, PaperCheng-Zhen Nie, Hao Liu, Xu-Hui Huang, Da-Yong Zhou, Xu-Song Wang, Lei Qin Non-targeted analysis of high-resolution mass spectrometry (MS) can identify thousands of compounds, which also gives a huge challenge to their quantification. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - April 18, 2024 Category: Chemistry Authors: Cheng-Zhen Nie Source Type: research

Most People Experiencing Homelessness Have Mental Health Disorders, Study Finds
Sixty-seven percent of people experiencing homelessness worldwide have a mental health disorder, according to areport published yesterday inJAMA Psychiatry. Additionally, the prevalence of mental health disorders among this population appears to be on the rise.“The relationship between mental health disorders and homelessness is complex and bidirectional,” wrote Rebecca Barry, Ph.D., of the University of Calgary and colleagues. “[M]ental health disorders may lead to situations that result in homelessness, or homelessness may be a stressor contributi ng to the development or worsening of mental health disorder symptom...
Source: Psychiatr News - April 18, 2024 Category: Psychiatry Tags: antisocial personality disorder homeless JAMA Psychiatry mental health disorders meta-analysis North America Rebecca Barry schizophrenia substance use disorders systematic review University of Calgary Source Type: research

Daring ‘James Bond’ mission to drill Antarctic ices cores could reveal future of sea level rise
The helicopter hovered overhead, whipping up snow. Shielding his face, Peter Neff grabbed the dangling cargo load and guided it to the Antarctic ice. The helicopter sped back to the South Korean icebreaker RV Araon , 20 kilometers away, to fetch more gear. One trip down, 17 more to go, thought Neff, a polar glaciologist at the University of Minnesota (UM) Twin Cities. Time was ticking away on this day in January. In the best-case scenario, Neff and his team would have just 10 days to drill ice cores on Canisteo, a peninsula on the west coast of Antarctica—and a blizzard was already looming. Ever...
Source: Science of Aging Knowledge Environment - April 18, 2024 Category: Geriatrics Source Type: research

Accelerating Scientific Discovery With AI-Aided Automation
AI-aided design of experiments and observations, together with robotic instrumentation and automated learning from data, has the potential to transform science and propel it forward with unprecedented speed. (Source: Computing in Science and Engineering)
Source: Computing in Science and Engineering - April 18, 2024 Category: Information Technology Source Type: research

Performance on HPC Platforms Is Possible Without C++
We describe some of the presentations and discussion from the mini symposium in this article. (Source: Computing in Science and Engineering)
Source: Computing in Science and Engineering - April 18, 2024 Category: Information Technology Source Type: research

Inflammatory breast cancer (IBC) advocacy-Past, present and future!
In conclusion, in defining the evolving roles of Patient Advocacy in IBC over the past 25 years, we examine what has been done, along with its challenges, and what work still remains from the perspectives of different patient advocates.PMID:38637097 | DOI:10.1016/bs.ircmb.2023.11.001 (Source: International Review of Cell and Molecular Biology)
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Jeannine Donahue Joshlyn Earls Valerie Fraser Ginny Mason Heather Pirowski Peggy Stephens Source Type: research

Bisphenol-F and Bisphenol-S (BPF and BPS) Impair the Stemness of Neural Stem Cells and Neuronal Fate Decision in the Hippocampus Leading to Cognitive Dysfunctions
Mol Neurobiol. 2024 Apr 18. doi: 10.1007/s12035-024-04160-1. Online ahead of print.ABSTRACTNeurogenesis occurs throughout life in the hippocampus of the brain, and many environmental toxicants inhibit neural stem cell (NSC) function and neuronal generation. Bisphenol-A (BPA), an endocrine disrupter used for surface coating of plastic products causes injury in the developing and adult brain; thus, many countries have banned its usage in plastic consumer products. BPA analogs/alternatives such as bisphenol-F (BPF) and bisphenol-S (BPS) may also cause neurotoxicity; however, their effects on neurogenesis are still not known. ...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Saurabh Tiwari None Phoolmala Shweta Goyal Ranjeet Kumar Yadav Rajnish Kumar Chaturvedi Source Type: research

Identification of biomarkers and immune infiltration characterization of lipid metabolism associated genes in osteoarthritis based on machine learning algorithms
Aging (Albany NY). 2024 Apr 17;16. doi: 10.18632/aging.205740. Online ahead of print.ABSTRACTOsteoarthritis (OA) is a prevalent degenerative condition commonly observed in the elderly, leading to consequential disability. Despite notable advancements made in clinical strategies for OA, its pathogenesis remains uncertain. The intricate association between OA and metabolic processes has yet to receive comprehensive exploration. In our investigation, we leveraged public databases and applied machine learning algorithms, including WGCNA, LASSO, RF, immune infiltration analysis, and pathway enrichment analysis, to scrutinize th...
Source: Aging - April 18, 2024 Category: Biomedical Science Authors: Yuanye Ma Yang Liu Dan Luo Zhu Guo Hongfei Xiang Bohua Chen Xiaolin Wu Source Type: research