Impact of periventricular hyperintensities and cystatin C on different cognitive domains in the population of non-demented elderly Chinese
ConclusionsWe demonstrated that in the chinese non-demented elderly, the severity of PVH was independent and significant associated with mild cognitive impairment and that the primary impairment was executive capacity and processing speed, while cystatin C may be an independent risk factor for overall cognitive impairment. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - July 13, 2019 Category: Neuroscience Source Type: research

Does restricting hand gestures impair mathematical reasoning?
Publication date: December 2019Source: Learning and Instruction, Volume 64Author(s): Candace Walkington, Dawn Woods, Mitchell J. Nathan, Geoffrey Chelule, Min WangAbstractGestures are associated with powerful forms of understanding; however, their causative role in mathematics reasoning is less clear. We inhibit college students' gestures by restraining their hands, and examine the impact on language, recall, intuition, and mathematical justifications of geometric conjectures. We test four mutually exclusive hypotheses: (1) gestures are facilitative, through cognitive off-loading, verbal support, or transduction, (2) gestu...
Source: Learning and Instruction - July 13, 2019 Category: Psychiatry & Psychology Source Type: research

Automatic estimation of heading date of paddy rice using deep learning
Accurate estimation of heading date of paddy rice greatly helps the breeders to understand the adaptability of different crop varieties in a given location. The heading date also plays a vital role in determin... (Source: Plant Methods)
Source: Plant Methods - July 13, 2019 Category: Biology Authors: Sai Vikas Desai, Vineeth N. Balasubramanian, Tokihiro Fukatsu, Seishi Ninomiya and Wei Guo Tags: Methodology Source Type: research

Economic analysis of a low-cost virtual surgical planning protocol for mandibular reconstruction: a case series
Publication date: Available online 11 July 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): C. Spaas, O. LenssenAbstractThe aim of this study was to make an economic analysis and evaluation of a low-cost virtual surgical planning (VSP) protocol that was developed in house, and based on open-source software and a desktop 3-dimensional printer. All eight patients between April 2014 and 2015 who had been treated by mandibular reconstructions with microvascular fibular flaps that had been planned using the protocol were retrospectively analysed for accuracy, time, and cost.Median differences for planned ...
Source: British Journal of Oral and Maxillofacial Surgery - July 13, 2019 Category: ENT & OMF Source Type: research

Frugal innovation in the cardiac catheter laboratory: Retrograde balloon mitral valvuloplasty using extra back-up guide catheter
We report a case of rheumatic heart disease with severe mitral stenosis and large atrial septal aneurysm where balloon mitral valvuloplasty was performed retrogradely with innovative use of routinely available cardiac catheter laboratory hardware instead of specialised hardware required for such cases. (Source: Journal of Cardiology Cases)
Source: Journal of Cardiology Cases - July 13, 2019 Category: Cardiology Source Type: research

Anatomy dissection course improves the initially lower levels of visual ‐spatial abilities of medical undergraduates
This article is protected by copyright. All rights reserved. (Source: Anatomical Sciences Education)
Source: Anatomical Sciences Education - July 13, 2019 Category: Anatomy Authors: Katerina Bogomolova, Beerend P. Hierck, Jos A. van der Hage, Steven E.R. Hovius Tags: Research Report Source Type: research

Improving Operating Room Efficiency: A Machine Learning Approach to Predict Case-Time Duration
Accurate estimation of operative case-time duration is critical for optimizing operating room utilization. Current estimates are inaccurate and prior models include data not available at the time of scheduling. Our objective was to develop statistical models in a large retrospective dataset to improve estimation of case-time duration relative to current standards. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - July 13, 2019 Category: Surgery Authors: Matthew A. Bartek, Rajeev C. Saxena, Stuart Solomon, Christine T. Fong, Lakshmana D. Behara, Ravitheja Venigandla, Kalyani Velagapudi, John D. Lang, Bala G. Nair Tags: Original Scientific Article Source Type: research

The learning curve for performing three-column osteotomies in adult spinal deformity patients: one surgeon's experience with 197 cases
Three-column osteotomy (3CO) is used to correct rigid adult spinal deformity. It presents risk of complications because it involves extensive osseous resection and spinal destabilization. (Source: The Spine Journal)
Source: The Spine Journal - July 13, 2019 Category: Orthopaedics Authors: Micheal Raad, Varun Puvanesarajah, Andrew Harris, Mostafa H. El Dafrawy, Morsi Khashan, Amit Jain, Hamid Hassanzadeh, Khaled M. Kebaish Tags: Clinical Study Source Type: research

Sensors, Vol. 19, Pages 3106: Automated Counting of Rice Panicle by Applying Deep Learning Model to Images from Unmanned Aerial Vehicle Platform
u Guijun Yang The number of panicles per unit area is a common indicator of rice yield and is of great significance to yield estimation, breeding, and phenotype analysis. Traditional counting methods have various drawbacks, such as long delay times and high subjectivity, and they are easily perturbed by noise. To improve the accuracy of rice detection and counting in the field, we developed and implemented a panicle detection and counting system that is based on improved region-based fully convolutional networks, and we use the system to automate rice-phenotype measurements. The field experiments were conducted in ta...
Source: Sensors - July 13, 2019 Category: Biotechnology Authors: Chengquan Zhou Hongbao Ye Jun Hu Xiaoyan Shi Shan Hua Jibo Yue Zhifu Xu Guijun Yang Tags: Article Source Type: research

Use of multimedia during informed consent: novelty or necessity
AbstractThe process of informed consent is an integral part of the preoperative encounter. In theory, it has the potential to educate patients, enabling them to reach a true autonomous decision regarding the treatment offered. Unfortunately, in recent years informed consent has become overly complicated for the average patient. Questions have been raised regarding the ability of the process, as practiced nowadays, to actually increase knowledge and achieve its goals. In search of new ways to increase patient comprehension, researchers have suggested use of multimedia during the process of informed consent. Visualization of...
Source: International Urogynecology Journal - July 13, 2019 Category: OBGYN Source Type: research

The Application of Deep Learning in the Risk Grading of Skin Tumors for Patients Using Clinical Images
AbstractAccording to diagnostic criteria, skin tumors can be divided into three categories: benign, low degree and high degree malignancy. For high degree malignant skin tumors, if not detected in time, they can do serious harm to patients ’ health. However, in clinical practice, identifying malignant degree requires biopsy and pathological examination which is time costly. Furthermore, in many areas, due to the severe shortage of dermatologists, it’s inconvenient for patients to go to hospital for examination. Therefore, an easy to access screening method of malignant skin tumors is needed urgently. Firstly, w...
Source: Journal of Medical Systems - July 13, 2019 Category: Information Technology Source Type: research

A prospective evaluation of whole brain volume loss and neurocognitive decline following hippocampal-sparing prophylactic cranial irradiation for limited-stage small-cell lung cancer
This study evaluated an association between whole brain volume loss and neurocognitive decline following prophylactic cranial irradiation (PCI) for limited-stage small-cell lung cancer (SCLC).MethodsThis was a secondary analysis of a prospective clinical trial that accrued patients at a single institution from 2013 to 2016. Patients with limited-stage SCLC treated with standard chemo-radiation received PCI 25  Gy/10 fractions, with mean hippocampal dose limited to 
Source: Journal of Neuro-Oncology - July 13, 2019 Category: Cancer & Oncology Source Type: research

Anticipatory effect of execution on observation: an approach using ExoPinch finger robot
Conclusion: The results showed an interaction effect of kinetics features and hemisphere at frontal channels corresponding nearly to the ventral premotor cortex area of the brain. The activation of mirror neurons in this area plays a crucial role in observational learning. Based on our results, we propose that specific type of visual stimuli can be combined with the functional abilities of the MNS in the action observation based treatment of hand motor dysfunction of stroke patients to have a positive additional impact. PMID: 31293146 [PubMed - as supplied by publisher] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - July 12, 2019 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Targeting separate specific learning parameters underlying cognitive behavioral therapy can improve perceptual judgments of anger
ConclusionsThis study demonstrates that specific decision parameters underlying perceptual judgment can be experimentally manipulated. Although our study failed to show diagnosis specific effects, it suggests that individual parameter “estimation” deficits may be experimentally isolated and potentially targeted, with the ultimate goal of developing an objective approach to personalized intervention targeting biased perceptual judgments in anxiety disorders. (Source: Journal of Behavior Therapy and Experimental Psychiatry)
Source: Journal of Behavior Therapy and Experimental Psychiatry - July 12, 2019 Category: Psychiatry Source Type: research

Early life stress amplifies fear responses and hippocampal synaptic potentiation in the APPswe/PS1dE9 Alzheimer mouse model.
Publication date: Available online 11 July 2019Source: NeuroscienceAuthor(s): Sylvie L. Lesuis, Paul J. Lucassen, Harm J. KrugersAbstractCognitive deficits and alterations in emotional behaviour are typical features of Alzheimer's disease (AD). Moreover, exposure to stress or adversity during the early life period has been associated with an acceleration of cognitive deficits and increased AD pathology in transgenic AD mouse models. Whether and how early life adversity affects fear memory in AD mice remains elusive.We therefore investigated whether exposure to early life stress (ELS) alters fear learning in APPswe/PS1dE9 m...
Source: Neuroscience - July 12, 2019 Category: Neuroscience Source Type: research

Protective Role of Levetiracetam Against Cognitive Impairment And Brain White Matter Damage in Mouse prolonged Cerebral Hypoperfusion
Publication date: Available online 11 July 2019Source: NeuroscienceAuthor(s): Toshiki Inaba, Nobukazu Miyamoto, Kenichiro Hira, Yuji Ueno, Kazuo Yamashiro, Masao Watanabe, Yoshiaki Shimada, Nobutaka Hattori, Takao UrabeAbstractWhite matter lesions due to cerebral hypoperfusion may be an important pathophysiology in vascular dementia and stroke, although the inherent mechanisms remain to be fully elucidated. The present study, using a mouse model of chronic cerebral hypoperfusion, examined the white matter protective effects of levetiracetam, an anticonvulsant, via the signaling cascade from the activation of cAMP-responsiv...
Source: Neuroscience - July 12, 2019 Category: Neuroscience Source Type: research

Post-Processing for Intra Coding through Perceptual Adversarial Learning and Progressive Refinement
Publication date: Available online 11 July 2019Source: NeurocomputingAuthor(s): Zhipeng Jin, Ping An, Chao Yang, Liquan ShenAbstractVideo compression is an indispensable technology in image/video communications, due to its highly desirable ability to reduce the huge data volume. However, video compression introduces complex compression artifacts, such as blocking, ringing, and blurring artifacts. To reduce this issue, post-processing techniques have been extensively studied. In this paper, we propose a novel post-processing technique using multi-level progressive refinement network, which we term MPRNet. A joint training l...
Source: Neurocomputing - July 12, 2019 Category: Neuroscience Source Type: research

Does Retrieval Enhance Suggestibility Because It Increases Perceived Credibility of the Postevent Information?
Publication date: Available online 12 July 2019Source: Journal of Applied Research in Memory and CognitionAuthor(s): Krista D. Manley, Jason C.K. ChanDespite the robust memory-enhancing benefits of retrieval practice, an initial test can sometimes exacerbate eyewitness’ susceptibility to subsequent misinformation—a phenomenon known as retrieval-enhanced suggestibility. One explanation for this finding is that after taking a memory test, participant witnesses are more likely to treat the subsequently presented misinformation narrative as being credible (the misinformation acceptance account; e.g., Chan, Manley, ...
Source: Journal of Applied Research in Memory and Cognition - July 12, 2019 Category: Neuroscience Source Type: research

Conceptualizing and measuring social and emotional learning: A systematic review and meta-analysis of moral reasoning and academic ability, religiosity, political orientation, personality
Publication date: Available online 11 July 2019Source: Educational Research ReviewAuthor(s): Roisin P. Corcoran, Joanne O’Flaherty, Chen Xie, Alan C.K. CheungAbstractResponsible decision-making is a sub-domain of social emotional competence and develops through the educational process of social and emotional learning (SEL). The current review examines the relationship between decision-making, specifically, moral reasoning (MR) and academic ability (N = 6,992, 18), MR and religiosity (N = 3,441, 15), MR and political orientation (N = 12,814, 14) and MR and personality (N = 1,659, 8). Forty-three studies qualified for ...
Source: Educational Research Review - July 12, 2019 Category: Child Development Source Type: research

Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism.
Authors: Storbeck KH, Schiffer L, Baranowski ES, Chortis V, Prete A, Barnard L, Gilligan LC, Taylor AE, Idkowiak J, Arlt W, Shackleton CHL Abstract Steroid biosynthesis and metabolism is reflected by the serum steroid metabolome and, in even more detail, by the 24-hour urine steroid metabolome, which can provide unique insights into alterations of steroid flow and output indicative of underlying conditions. Mass spectrometry-based steroid metabolome profiling has allowed for the identification of unique multi-steroid signatures associated with disorders of steroid biosynthesis and metabolism that can be used for pe...
Source: Endocrine Reviews - July 12, 2019 Category: Endocrinology Tags: Endocr Rev Source Type: research

Bio-banding in Academy Football: Player's Perceptions of a Maturity Matched Tournament.
Conclusions. Player's perceived the bio-banding format as providing two main benefits. Early maturing players perceived greater physical and technical challenge, and in turn new opportunities and challenges. Late maturing players perceived less physical and technical challenge, yet greater opportunity to demonstrate technical and tactical abilities. The players reported that they enjoyed and understood the purpose of the bio-banded format, and perceived less risk for injury. Players in all three maturity groups reported more opportunity to engage in leadership behaviours, influence game-play, and express themselves on the ...
Source: Annals of Human Biology - July 12, 2019 Category: Biology Tags: Ann Hum Biol Source Type: research

Four comments for the paper from Liu et al. (2019)
Publication date: Available online 11 July 2019Source: Journal of the Korean Statistical SocietyAuthor(s): Jorge Luis BazánAbstractWe give comments for the paper from Liu et al. (2019) about the Item Response Theory (IRT) model under consideration, the justification to compute Marginal likelihood, about what we learn with the data analysis performed and finally, about the computational issues in this paper. (Source: Journal of the Korean Statistical Society)
Source: Journal of the Korean Statistical Society - July 12, 2019 Category: Statistics Source Type: research

Physarum inspires research beyond biomimetic algorithms: Reply to comments on “Does being multi-headed make you better at solving problems?”
Publication date: Available online 11 July 2019Source: Physics of Life ReviewsAuthor(s): Chao Gao, Chen Liu, Daniel Schenz, Xuelong Li, Zili Zhang, Marko Jusup, Zhen Wang, Madeleine Beekman, Toshiyuki NakagakiAbstractWe look at a recent expansion of Physarum research from inspiring biomimetic algorithms to serving as a model organism in the evolutionary study of perception, memory, learning, and decision making. (Source: Physics of Life Reviews)
Source: Physics of Life Reviews - July 12, 2019 Category: Physics Source Type: research

Prodromal clinical, demographic, and socio-ecological correlates of asthma in adults: A 10-year statewide big data multi-domain analysis.
CONCLUSIONS: In this large statewide study using a machine learning approach, we found that a multi-domain approach with demographics, clinical, and socio-ecological variables best predicted an asthma diagnosis. Future work should focus on integrating machine learning-generated predictive models into clinical practice to improve early detection of those common respiratory diseases. PMID: 31288571 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - July 12, 2019 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Machine Learning Model to Predict Osteoporotic Spine with Hounsfield Units on Lumbar Computed Tomography.
CONCLUSION: This study is a simple machine learning model applicable in the spine research field. The machine learning model can predict the T-score and osteoporotic vertebrae solely by measuring the HU of conventional CT, and this would help spine surgeons not to under-estimate the osteoporotic spine preoperatively. If applied to a bigger data set, we believe the predictive accuracy of our model will further increase. We propose that machine learning is an important modality of the medical research field. PMID: 31290297 [PubMed] (Source: Journal of Korean Neurosurgical Society)
Source: Journal of Korean Neurosurgical Society - July 12, 2019 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

A Prediction Model for Uncontrolled Type 2 Diabetes Mellitus Incorporating Area-level Social Determinants of Health
Conclusions: A predictive model developed through a machine learning approach may assist health care organizations to identify which area-level SDH data to monitor for prediction of diabetes control, for potential use in risk-adjustment and targeting. (Source: Medical Care)
Source: Medical Care - July 12, 2019 Category: Health Management Tags: Original Articles Source Type: research

Traffic safety analysis on mixed traffic flows at signalized intersection based on Haar-Adaboost algorithm and machine learning
Publication date: December 2019Source: Safety Science, Volume 120Author(s): Quan Yu, Yuting ZhouAbstractMixed traffic is the typical characteristic of urban traffic in China. Especially on the crosswalks at signalized intersection, mixed traffic flow is large, traffic conflicts happen frequently. So, the traffic safety analysis is one of the research directions at signalized intersection. The main conflicts on the pedestrian crosswalk include the conflict among pedestrians and non-motorized vehicles as well as the conflict between the right-turning motor vehicles and pedestrians. Several impacts are imposed on the order of...
Source: Safety Science - July 12, 2019 Category: Occupational Health Source Type: research

Multi-institutional Surgical Education Interventions: A Scoping Review
Conclusions: Multi-institutional surgical education studies do not uniformly incorporate characteristics of high quality research, particularly related to study design, measurable outcomes, and assessment tools used. Coordinated support, including grant funding, that addresses the challenging nature of multi-institutional surgical education research may improve the quality of these studies. (Source: Annals of Surgery)
Source: Annals of Surgery - July 12, 2019 Category: Surgery Tags: REVIEW PAPER Source Type: research

Shared Neuromuscular Performance Traits in Military Personnel with Prior Concussion
Conclusion The findings supported the hypothesis that CONCUSSED military personnel would demonstrate altered neuromuscular control in landing strategies and muscular activation. Future research should assess prospectively neuromuscular changes after a concussion and determine if these changes increase risk of subsequent musculoskeletal injuries. (Source: Medicine and Science in Sports and Exercise)
Source: Medicine and Science in Sports and Exercise - July 12, 2019 Category: Sports Medicine Tags: CLINICAL SCIENCES Source Type: research

Judging own and peer performance when using feedback in elementary school
This study investigated 97 children's (52 fourth and 45 sixth grade) feedback use when scoring their own and their peers' concept learning. Children completed a concept-learning task, took a test, and then scored their own responses and the responses of one of their peers with use of feedback standards. Error detection was better for peer- than for self-score judgments. Further, monitoring was more accurate for older than younger children, and inaccurate prior knowledge led to less accurate peer and self-judgments. Findings imply that, when implementing co-scoring activities, it is important to be aware that its accuracy i...
Source: Learning and Individual Differences - July 12, 2019 Category: Psychiatry & Psychology Source Type: research

Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion
Publication date: Available online 10 July 2019Source: Neurochemistry InternationalAuthor(s): Elyssa B. Margolis, Anushree N. KarkhanisAbstractNeural circuits that enable an organism to protect itself by promoting escape from immediate threat and avoidance of future injury are conceptualized to carry an “aversive” signal. One of the key molecular elements of these circuits is the kappa opioid receptor (KOR) and its endogenous peptide agonist, dynorphin. In many cases, the aversive response to an experimental manipulation can be eliminated by selective blockade of KOR function, indicating its necessity in transm...
Source: Neurochemistry International - July 12, 2019 Category: Neuroscience Source Type: research

Deep learning enabled real time speckle recognition and hyperspectral imaging using a multimode fiber array
We demonstrate the use of deep learning for fast spectral deconstruction of speckle patterns. The artificial neural network can be effectively trained using numerically constructed multispectral datasets taken from a measured spectral transmission matrix. Optimized neural networks trained on these ... (Source: Optics Express)
Source: Optics Express - July 12, 2019 Category: Physics Authors: Ulas K ü r ü m Peter R. Wiecha Rebecca French Otto L. Muskens Source Type: research

[ASAP] Coupling the High-Throughput Property Map to Machine Learning for Predicting Lattice Thermal Conductivity
Chemistry of MaterialsDOI: 10.1021/acs.chemmater.9b01046 (Source: Chemistry of Materials)
Source: Chemistry of Materials - July 12, 2019 Category: Materials Science Authors: Rinkle Juneja †, George Yumnam†, Swanti Satsangi, and Abhishek K. Singh* Source Type: research

Referable Diabetic Retinopathy Identification from Eye Fundus Images with Weighted Path for Convolutional Neural Network
Publication date: Available online 10 July 2019Source: Artificial Intelligence in MedicineAuthor(s): Yi-Peng Liu, Zhanqing Li, Cong Xu, Jing Li, Ronghua LiangAbstractDiabetic retinopathy (DR) is the most common cause of blindness in middle-age subjects and low DR screening rates demonstrates the need for an automated image assessment system, which can benefit from the development of deep learning techniques. Therefore, the effective classification performance is significant in favor of the referable DR identification task. In this paper, we propose a new strategy, which applies multiple weighted paths into convolutional ne...
Source: Artificial Intelligence in Medicine - July 12, 2019 Category: Bioinformatics Source Type: research

Learning and behavior in hatchling Trachemys scripta exposed to bisphenol-a during embryonic development
Publication date: Available online 10 July 2019Source: Physiology & BehaviorAuthor(s): Justin Dillard, Amanda Wilson Carter, Geoff D. Ower, Ryan T. Paitz, R.M. BowdenAbstractSteroids play an integral role in orchestrating embryonic development, and they can affect a suite of phenotypic traits, including learning and behavior. Endocrine disrupting compounds (EDCs) can alter steroid-dependent phenotypic traits during embryonic development. Bisphenol-A (BPA) is an EDC that disrupts the action of estrogen, and recent work indicates that BPA can affect learning and behavior similarly to estrogen. We exposed red-eared slider...
Source: Physiology and Behavior - July 12, 2019 Category: Physiology Source Type: research

How a dialogic space can impact children’s creativity and mood valence in Drama Pedagogy Training: Study with a French 4th grade sample
Publication date: September 2019Source: Thinking Skills and Creativity, Volume 33Author(s): Macarena-Paz Celume, Maud Besançon, Franck ZenasniAbstractDrama Pedagogy Training (DPT) is a kind of training based on an active educational methodology called Drama Pedagogy. It is mostly based on collaborative drama games and techniques, similar to what is commonly found in literature as creative drama as the objective is neither artistic nor academic. As an active pedagogy, participants co-construct their learning through participative dialogue, reasoning together about the learning experiences that are presented as collab...
Source: Thinking Skills and Creativity - July 12, 2019 Category: Science Source Type: research

Interpretations of and management actions following electrocardiograms in symptomatic patients in primary care: a  retrospective dossier study.
CONCLUSION: GPs who feel competent in electrocardiography performed well in the opinion of the expert panel. We formulated various learning objectives for GPs performing electrocardiography. PMID: 31301001 [PubMed - as supplied by publisher] (Source: Netherlands Heart Journal)
Source: Netherlands Heart Journal - July 12, 2019 Category: Cardiology Authors: Wagenvoort LME, Willemsen RTA, Konings KTS, Stoffers HEJH Tags: Neth Heart J Source Type: research

The quality of child-directed speech depends on the speaker's language proficiency.
Abstract Many children learn language, in part, from the speech of non-native speakers who vary in their language proficiency. To investigate the influence of speaker proficiency on the quality of child-directed speech, 29 mothers who were native English speakers and 31 mothers who were native speakers of Spanish and who reported speaking English to their children on a regular basis were recorded interacting with their two-year-old children in English. Of the non-native speakers, 21 described their English proficiency as 'good', and eight described their English proficiency as 'limited'. ANCOVAs, controlling for d...
Source: Journal of Child Language - July 12, 2019 Category: Speech-Language Pathology Authors: Hoff E, Core C, Shanks KF Tags: J Child Lang Source Type: research

Buzz groups facilitate collaborative learning and improve histopathological competencies of students.
DISCUSSION: Collaborative BGs improve the learning of histopathological competencies. They motivate and activate students to learn. The course also increased the appreciation of students for histopathology. For BGs, digital microscopy was better suited than traditional analog microscopy. The application of BGs in the context of analyzing microscopic images should be disseminated and studied on larger cohorts.
. PMID: 31296286 [PubMed - as supplied by publisher] (Source: Clinical Neuropathology)
Source: Clinical Neuropathology - July 12, 2019 Category: Pathology Authors: Romeike BFM, Fischer M Tags: Clin Neuropathol Source Type: research

Pure topographical disorientation in novel environments without anterograde amnesia: a case study.
Abstract Topographical disorientation (TD) in novel environments is considered to be a part of anterograde amnesia. A 56-year-old woman presented with pure TD only in novel environments following limbic encephalitis. She could not remember directions inside the hospital on weekly outpatient visits; however, her verbal and visual anterograde memories were normal. In the test of learning photographs of scenes, faces, and objects, only her scores for landscapes were worse than those in healthy controls. These findings suggested that her TD specific to landscapes and directions in novel environments was caused by cate...
Source: Neurocase - July 12, 2019 Category: Neurology Authors: Oishi Y, Yamakawa T, Nagasawa H, Suzuki K Tags: Neurocase Source Type: research

Transdiagnostic validity of the MATRICS Consensus Cognitive Battery across the autism-schizophrenia spectrum.
CONCLUSIONS: To our knowledge, this study is the first to establish the validity of a standard cognitive battery in adults with ASD and furthermore the first to establish a cognitive battery's comparability across ASD and schizophrenia. Cognitive domain scores can be compared across new samples using weighted sums of MCCB scores resulting from this study. These findings highlight MCCB's applicability to ASD and support its utility for standardizing treatment evaluation of cognitive outcomes across the autism-schizophrenia spectrum. PMID: 31298174 [PubMed - as supplied by publisher] (Source: Psychological Medicine)
Source: Psychological Medicine - July 12, 2019 Category: Psychiatry Authors: Kuo SS, Wojtalik JA, Mesholam-Gately RI, Keshavan MS, Eack SM Tags: Psychol Med Source Type: research

Comparison of financial support for family caregivers of people at the end of life across six countries: A descriptive study.
CONCLUSION: Numerous barriers exist to the receipt of financial support, welfare and benefits. We identified several areas of concern, including a lack of clarity around eligibility, inconsistent implementation, complexity in process and limited support for working carers. Nonetheless, there is significant potential for policymakers to learn from other countries' experiences, particularly with regard to the scope and operationalisation of financial support. PMID: 31296108 [PubMed - as supplied by publisher] (Source: Palliative Medicine)
Source: Palliative Medicine - July 12, 2019 Category: Palliative Care Authors: Gardiner C, Taylor B, Robinson J, Gott M Tags: Palliat Med Source Type: research

Information-theoretic analysis of multivariate single-cell signaling responses
by Tomasz Jetka, Karol Niena łtowski, Tomasz Winarski, Sławomir Błoński, Michał Komorowski Mathematical methods of information theory appear to provide a useful language to describe how stimuli are encoded in activities of signaling effectors. Exploring the information-theoretic perspective, however, remains conceptually, experimentally and computationally challenging. Specifically, exi sting computational tools enable efficient analysis of relatively simple systems, usually with one input and output only. Moreover, their robust and readily applicable implementations are missing. Here, we propose a novel algorithm, S...
Source: PLoS Computational Biology - July 12, 2019 Category: Biology Authors: Tomasz Jetka Source Type: research

Motor Competence Levels and Developmental Delay in Early Childhood: A Multicenter Cross-Sectional Study Conducted in the USA
ConclusionsDevelopmental delay in motor competence is an emerging epidemic that needs to be systematically acknowledged and addressed in the USA. By shifting norms based upon current data, there may be a lower standard of “typical development” that may have profound effects on factors that support long-term health. (Source: Sports Medicine)
Source: Sports Medicine - July 12, 2019 Category: Sports Medicine Source Type: research

Advantages of an Anterior Based Muscle Sparing Approach (ABMS) in Transitioning from a Posterior Approach for Total Hip Arthroplasty: Minimizing the Learning Curve.
This study aimed to investigate if there was a difference in perioperative variables, intra-operative and immediate post-operative complications or patient reported outcomes (PROs) when transitioning from a mini-posterior approach (mPA) to an anterior based muscle sparing (ABMS) approach for THA. (Source: The Journal of Arthroplasty)
Source: The Journal of Arthroplasty - July 12, 2019 Category: Orthopaedics Authors: Ryland Kagan, Eric M. Greber, Stephen M. Richards, Jill A. Erickson, Mike B. Anderson, Christopher L. Peters Source Type: research

Primary Care Providers Believe That Comprehensive Medication Management Improves Their Work-Life
Conclusion: Our findings suggest PCPs believe CMM, in general, positively affects their work-life. CMM's impact on PCPs aligns with many previously identified drivers of burnout and engagement among providers. These results shed light on how CMM may foster achievement of the Quadruple Aim. (Source: Journal of the American Board of Family Medicine)
Source: Journal of the American Board of Family Medicine - July 12, 2019 Category: Primary Care Authors: Funk, K. A., Pestka, D. L., Roth McClurg, M. T., Carroll, J. K., Sorensen, T. D. Tags: Original Research Source Type: research

Effect of mobile learning (application) on self-care behaviors and blood glucose of type 2 diabetic patients
ConclusionsThe results indicated the positive effect of the mobile application on self-care behavior, FBS, and HbA1C. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - July 12, 2019 Category: Endocrinology Source Type: research

Staging System to Predict the Risk of Relapse in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Over the last decade autologous stem cell transplantation (ASCT) has emerged as the standard of care in the management of Multiple Myeloma (MM). However, the cases of early relapse (within 36 months) after the stem cell rescue remains a significant challenge. For a lot of practical purposes, it is crucial to identify whether a patient undergoing ASCT falls into the high-risk group (likely to relapse within 36 months) or a low risk one. Our analysis showed that existing MM staging systems (International Staging System or ISS and Durie Salmon Staging or DSS) are not sufficient to discriminate between the risk groups si...
Source: Frontiers in Oncology - July 12, 2019 Category: Cancer & Oncology Source Type: research

Early Substance Use Cessation Improves Cognition —10 Years Outcome in First-Episode Psychosis Patients
This study is one of very few long-term studies on cognitive impairments in first episode psychosis focusing explicitly on substance use. Early cessation of substance use was associated with less cognitive impairment and some improvement over time on some cognitive measures, indicating a milder illness course and superior cognitive reserves to draw from in recovering from psychosis. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - July 12, 2019 Category: Psychiatry Source Type: research

Sensors, Vol. 19, Pages 3079: Deep PPG: Large-Scale Heart Rate Estimation with Convolutional Neural Networks
erhoven Photoplethysmography (PPG)-based continuous heart rate monitoring is essential in a number of domains, e.g., for healthcare or fitness applications. Recently, methods based on time-frequency spectra emerged to address the challenges of motion artefact compensation. However, existing approaches are highly parametrised and optimised for specific scenarios of small, public datasets. We address this fragmentation by contributing research into the robustness and generalisation capabilities of PPG-based heart rate estimation approaches. First, we introduce a novel large-scale dataset (called PPG-DaLiA), including a w...
Source: Sensors - July 12, 2019 Category: Biotechnology Authors: Attila Reiss Ina Indlekofer Philip Schmidt Kristof Van Laerhoven Tags: Article Source Type: research