Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH)
Condition:   Histiocytosis, Langerhans-Cell Interventions:   Other: Biospecimen Collection;   Other: Laboratory Biomarker Analysis;   Other: Questionnaire Administration Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 24, 2019 Category: Research Source Type: clinical trials

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders
Conditions:   Langerhan's Cell Histiocytosis;   Juvenile Xanthogranuloma;   Erdheim-Chester Disease;   Rosai Dorfman Disease;   Neuro-Degenerative Disease;   Histiocytic Sarcoma;   Histiocytic Disorders, Malignant Intervention:   Drug: Cobimetinib Sponsors:   Carl Allen;   Texas Children's Hospital;   North American Consortium for Histiocytosis;   Genentech, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 5, 2019 Category: Research Source Type: clinical trials