Early Phase Clinical Trials in Imaging and Image-Guided Interventions (R01 Clinical Trial Required)
Funding Opportunity PAR-18-011 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is intended to support clinical trials conducting preliminary evaluation of the safety and efficacy of imaging agents, as well as an assessment of imaging systems, image processing, image-guided planning and/or execution therapy, contrast kinetic modeling, 3-D reconstruction and other quantitative tools. As many such preliminary evaluations are early in development, this FOA will provide investigators with support for pilot (Phase I and II) cancer imaging clinical trials, including patient monitoring a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 6, 2017 Category: Research Source Type: funding

Systems Biology Approaches using Non-Mammalian Laboratory Animals to Uncover Causes of Neurodegeneration that Might Underlie Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-18-021 from the NIH Guide for Grants and Contracts. The National Institute on Aging is seeking applications on systems biology approaches using non-mammalian laboratory animal models to increase our understanding of the basic biology underpinning neurodegeneration. It is expected that research supported under this FOA will provide new insights into molecular networks that might be involved in causing, amplifying or protecting against neurodegeneration, and that, in turn, might ultimately contribute to Alzheimer's disease or related dementias. Importantly, a major goal of this FOA is to use int...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 6, 2017 Category: Research Source Type: funding

NCI Research Specialist (Laboratory-based Scientist) Award (R50)
Funding Opportunity PAR-18-341 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications for the Research Specialist Award (R50) in any area of NCI-funded cancer research. This FOA is specifically for laboratory-based scientists. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2017 Category: Research Source Type: funding

A Sampling of Recent Literature on the Scientific Workforce
As NIH continues its work to better understand the many factors that influence the stability of the biomedical workforce, we wanted to take a moment to discuss some recent papers that highlight the need to take new measures to support early and mid-career researchers. Earlier this year, we discussed a paper by our NIH colleagues who looked at data on the shifting demographics of lead principal investigators (PIs) on NIH and National Heart Lung and Blood Institute (NHLBI) research project grants. One of their findings is a decline in the representation of PIs aged 41-55. A recent paper by Michael Levitt (Stanford University...
Source: NIH Extramural Nexus - October 18, 2017 Category: Research Authors: Mike Lauer Tags: Open Mike Biomedical Workforce Early Stage Investigators Source Type: funding

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01)
Funding Opportunity RFA-NS-18-010 from the NIH Guide for Grants and Contracts. Invasive surgical procedures provide the unique ability to record and stimulate neurons within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and resources available to implement complex experimental protocols and are rarely aggregated in a manner that addresses research questions with appropriate statistical power. Therefore, this FOA seeks applications to assemble integrated, multi-disciplinary teams to overcome these fundamental barriers. Project...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 5, 2017 Category: Research Source Type: funding

Development of Valid Reliable Markers of Aging-Related Biologic Mechanisms for Human Studies (U01)
Funding Opportunity RFA-AG-18-018 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications to develop valid markers to assess the activity of fundamental aging mechanisms in humans that may influence the risk and progression of multiple aging conditions. Projects are encouraged that focus on selected mechanism(s) that may regulate aging changes, assess multiple possible markers for these mechanisms, test methods to improve their measurement properties, characterize their variability among individuals of differing ages and within the same age cohort, and assess thei...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 21, 2017 Category: Research Source Type: funding

Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Data Coordinating Center (U24)
Funding Opportunity RFA-DK-17-503 from the NIH Guide for Grants and Contracts. The NIDDK, in collaboration with the NHLBI and NICHD, invites Cooperative Agreement applications for a limited competition from the Data Coordinating Center (DCC) for The Chronic Kidney Disease in Children (CKiD) consortium. The DCC will work cooperatively with the existing Clinical Coordinating Centers (CCCs) and Central Biochemistry Laboratory (CBL) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Renal Disease (ESRD). (Source: NIH Funding Opportu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 17, 2017 Category: Research Source Type: funding

Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Clinical Coordinating Centers (U01)
Funding Opportunity RFA-DK-17-502 from the NIH Guide for Grants and Contracts. The NIDDK, in collaboration with the NHLBI and NICHD, invites Cooperative Agreement applications for a limited competition from the two Clinical Coordinating Centers (CCCs) already involved in The Chronic Kidney Disease in Children (CKiD) consortium. The Clinical Centers will continue to evaluate enrolled participants, recruit new participants, and continue to work together cooperatively with the existing Data Coordinating Center (DCC) and Central Biochemistry Laboratory (CBL) of the study as a Consortium. Participant evaluations in some doma...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 17, 2017 Category: Research Source Type: funding

Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24)
Funding Opportunity RFA-DK-17-034 from the NIH Guide for Grants and Contracts. The NIDDK invites Cooperative Agreement applications for an open competition for the Central Biochemistry Laboratory (CBL) of The Chronic Kidney Disease in Children (CKiD) consortium. The CBL will work cooperatively with the existing Clinical Coordinating Centers (CCCs) and Data Coordinating Center (DCC) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Renal Disease (ESRD). (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 17, 2017 Category: Research Source Type: funding

Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Data Coordinating Center (U24)
The NIDDK, in collaboration with the NHLBI and NICHD, invites Cooperative Agreement applications for a limited competition from the Data Coordinating Center (DCC) for The Chronic Kidney Disease in Children (CKiD) consortium. The DCC will work cooperatively with the existing Clinical Coordinating Centers (CCCs) and Central Biochemistry Laboratory (CBL) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Renal Disease (ESRD). (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - August 17, 2017 Category: Endocrinology Source Type: funding

Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Clinical Coordinating Centers (U01)
The NIDDK, in collaboration with the NHLBI and NICHD, invites Cooperative Agreement applications for a limited competition from the two Clinical Coordinating Centers (CCCs) already involved in The Chronic Kidney Disease in Children (CKiD) consortium. The Clinical Centers will continue to evaluate enrolled participants, recruit new participants, and continue to work together cooperatively with the existing Data Coordinating Center (DCC) and Central Biochemistry Laboratory (CBL) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Rena...
Source: NIDDK Funding Opportunities - August 17, 2017 Category: Endocrinology Source Type: funding

Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24)
The NIDDK invites Cooperative Agreement applications for an open competition for the Central Biochemistry Laboratory (CBL) of The Chronic Kidney Disease in Children (CKiD) consortium. The CBL will work cooperatively with the existing Clinical Coordinating Centers (CCCs) and Data Coordinating Center (DCC) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Renal Disease (ESRD). (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - August 17, 2017 Category: Endocrinology Source Type: funding

Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Data Coordinating Center (U24)
The NIDDK, in collaboration with the NHLBI and NICHD, invites Cooperative Agreement applications for a limited competition from the Data Coordinating Center (DCC) for The Chronic Kidney Disease in Children (CKiD) consortium. The DCC will work cooperatively with the existing Clinical Coordinating Centers (CCCs) and Central Biochemistry Laboratory (CBL) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Renal Disease (ESRD). (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - August 17, 2017 Category: Endocrinology Source Type: funding

Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Clinical Coordinating Centers (U01)
The NIDDK, in collaboration with the NHLBI and NICHD, invites Cooperative Agreement applications for a limited competition from the two Clinical Coordinating Centers (CCCs) already involved in The Chronic Kidney Disease in Children (CKiD) consortium. The Clinical Centers will continue to evaluate enrolled participants, recruit new participants, and continue to work together cooperatively with the existing Data Coordinating Center (DCC) and Central Biochemistry Laboratory (CBL) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Rena...
Source: NIDDK Funding Opportunities - August 17, 2017 Category: Endocrinology Source Type: funding

Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24)
The NIDDK invites Cooperative Agreement applications for an open competition for the Central Biochemistry Laboratory (CBL) of The Chronic Kidney Disease in Children (CKiD) consortium. The CBL will work cooperatively with the existing Clinical Coordinating Centers (CCCs) and Data Coordinating Center (DCC) of the study as a Consortium. Participant evaluations in some domains will be expanded, and follow-up will extend beyond the onset of End Stage Renal Disease (ESRD). (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - August 17, 2017 Category: Endocrinology Source Type: funding