Clinical features, diagnosis and management of amoxicillin-induced Kounis syndrome
Conclusion: KS is a rare adverse reaction of amoxicillin. Amoxicillin-induced KS should be considered when chest pain accompanied by allergic symptoms, electrocardiogram changes and or elevated levels of myocardial injury markers. Therapeutic management of KS requires simultaneous treatment of cardiac and allergic symptoms. Epinephrine should be used with caution in patients with suspected KS. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 31, 2022 Category: Drugs & Pharmacology Source Type: research

Cases of allergic coronary syndrome (Kounis syndrome) : what we should know
We present four cases of acute coronary syndrome developing after insect bites, chemotherapy, and coronary stent implantation. Two patients were lost due to anaphylactic shock-related multiorgan failures and sudden cardiac death. Since a wide range of drugs, foods, environmental conditions, and disease states may be associated with KS, all physicians must be aware of the syndrome.PMID:36237895 | PMC:PMC9529627 | DOI:10.18999/nagjms.84.3.664 (Source: Nagoya Journal of Medical Science)
Source: Nagoya Journal of Medical Science - October 14, 2022 Category: International Medicine & Public Health Authors: T ürkay Akbaş Adnan Kaya G ülşah Altun Ümit Eşbah Attila Önmez Source Type: research