Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics
In this study, we aimed to understand the structural basis for the elevated protease action of actinidin against gliadin peptides by using an in silico approach. Docking experiments revealed key differences between the binding of gliadin peptide to actinidin and papain, which may be responsible for their differential digestive action. Sequence comparison of different plant cysteine proteases highlights amino acid residues surrounding the active site pocket of actinidin that are unique to this molecule and hence likely to contribute to its digestive properties.PMID:37592795 | DOI:10.2174/0929866530666230817141100 (Source: P...
Source: Protein and Peptide Letters - August 18, 2023 Category: Biochemistry Authors: Shivangi Puja Shreya Seth Rachna Hora Satinder Kaur Prakash Chandra Mishra Source Type: research

Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics
In this study, we aimed to understand the structural basis for the elevated protease action of actinidin against gliadin peptides by using an in silico approach. Docking experiments revealed key differences between the binding of gliadin peptide to actinidin and papain, which may be responsible for their differential digestive action. Sequence comparison of different plant cysteine proteases highlights amino acid residues surrounding the active site pocket of actinidin that are unique to this molecule and hence likely to contribute to its digestive properties.PMID:37592795 | DOI:10.2174/0929866530666230817141100 (Source: P...
Source: Protein and Peptide Letters - August 18, 2023 Category: Biochemistry Authors: Shivangi Puja Shreya Seth Rachna Hora Satinder Kaur Prakash Chandra Mishra Source Type: research

Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics
In this study, we aimed to understand the structural basis for the elevated protease action of actinidin against gliadin peptides by using an in silico approach. Docking experiments revealed key differences between the binding of gliadin peptide to actinidin and papain, which may be responsible for their differential digestive action. Sequence comparison of different plant cysteine proteases highlights amino acid residues surrounding the active site pocket of actinidin that are unique to this molecule and hence likely to contribute to its digestive properties.PMID:37592795 | DOI:10.2174/0929866530666230817141100 (Source: P...
Source: Protein and Peptide Letters - August 18, 2023 Category: Biochemistry Authors: Shivangi Puja Shreya Seth Rachna Hora Satinder Kaur Prakash Chandra Mishra Source Type: research

Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics
In this study, we aimed to understand the structural basis for the elevated protease action of actinidin against gliadin peptides by using an in silico approach. Docking experiments revealed key differences between the binding of gliadin peptide to actinidin and papain, which may be responsible for their differential digestive action. Sequence comparison of different plant cysteine proteases highlights amino acid residues surrounding the active site pocket of actinidin that are unique to this molecule and hence likely to contribute to its digestive properties.PMID:37592795 | DOI:10.2174/0929866530666230817141100 (Source: P...
Source: Protein and Peptide Letters - August 18, 2023 Category: Biochemistry Authors: Shivangi Puja Shreya Seth Rachna Hora Satinder Kaur Prakash Chandra Mishra Source Type: research

Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics
In this study, we aimed to understand the structural basis for the elevated protease action of actinidin against gliadin peptides by using an in silico approach. Docking experiments revealed key differences between the binding of gliadin peptide to actinidin and papain, which may be responsible for their differential digestive action. Sequence comparison of different plant cysteine proteases highlights amino acid residues surrounding the active site pocket of actinidin that are unique to this molecule and hence likely to contribute to its digestive properties.PMID:37592795 | DOI:10.2174/0929866530666230817141100 (Source: P...
Source: Protein and Peptide Letters - August 18, 2023 Category: Biochemistry Authors: Shivangi Puja Shreya Seth Rachna Hora Satinder Kaur Prakash Chandra Mishra Source Type: research

Molecules, Vol. 28, Pages 6113: Effect of Processing on Reduction in Chiral Pesticide Hexaconazole for Kiwifruit Juice
In this study, the residue levels of chiral pesticide hexaconazole during kiwifruit juice processing (peeling, homogenization, and sterilization) were investigated by using high-performance liquid chromatography (HPLC), and the dietary risk during these processes was also assessed. Hexaconazole was applied at dosages of 173.33 and 346.66 mg/L (recommended and double recommended dosage) in kiwifruit. In the peeling process, 87.7% to 89.2% of the residues were decreased after peeling. Levels of hexaconazole residues in homogenization and sterilization processes further increased from 0.49% to 24.3% and from 0.2% to 3.0%, res...
Source: Molecules - August 17, 2023 Category: Chemistry Authors: Zelan Wang Min Wang Tianming Yang Yao Wang Dali Sun Junxiao Pang Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6036: Characterization of Bioactivity of Selective Molecules in Fruit Wines by FTIR and NMR Spectroscopies, Fluorescence and Docking Calculations
ela Gorinstein Fourier transform infrared (FTIR) and proton nuclear magnetic resonance (1H NMR) spectroscopies were applied to characterize and compare the chemical shifts in the polyphenols’ regions of some fruit wines. The obtained results showed that FTIR spectra (1800–900 cm−1) and 1H NMR (δ 6.5–9.3 ppm) of different fruit wines can be used as main indices of the year of vintage and quality of fruit wines. In addition to the classical determination of antioxidant profiles and bioactive substances in wines, fluorometric measurements were used to d...
Source: Molecules - August 12, 2023 Category: Chemistry Authors: Young-Mo Kim Martyna Lubinska-Szczyge ł Yong-Seo Park Joseph Deutsch Aviva Ezra Patraporn Luksrikul Raja Mohamed Beema Shafreen Shela Gorinstein Tags: Article Source Type: research

The Association Between the Number of Vacuum Pop-Offs and Adverse Neonatal Outcomes
Vacuum-assisted vaginal delivery (VAVD) is used to expedite vaginal delivery in cases of an arrest of descent, maternal exhaustion, or concern for fetal well-being. In 2015, the rate of VAVD was greater than the use of forceps in the United States (2.58% vs 0.56%). Several studies have examined various characteristics of vacuum devices, such as cup shape and material, number of pulls, and number of pop-ups, which is defined as the spontaneous dislodgment of the cup from the fetal scalp. Vacuum manufacturers, such as Kiwi and Mityvac, recommend abandoning VAVD as an intervention after 2 or 3 pop-offs; however, the American ...
Source: Obstetrical and Gynecological Survey - August 1, 2023 Category: OBGYN Tags: OBSTETRICS: MANAGEMENT OF LABOR, DELIVERY, AND THE PUERPERIUM Source Type: research

Combined effects of ethylene scavenging ‐active packaging system and modified atmosphere to reduce postharvest losses of ethylene sensitive produce: Banana and kiwifruit
In conclusion, bananas packaged with both active systems were acceptable for 9 d considering physicochemical and sensory properties. The kiwifruit was acceptable for 30 d using both ethylene absorbing systems under passive MAP. (Source: Packaging Technology and Science)
Source: Packaging Technology and Science - July 21, 2023 Category: Food Science Authors: Meliha Öztürk, Zehra Ayhan Tags: RESEARCH ARTICLE Source Type: research

Molecules, Vol. 28, Pages 5310: Efficient and Selective Adsorption of Cationic Dye Malachite Green by Kiwi-Peel-Based Biosorbents
In this study, pristine kiwi peel (KP) and nitric acid modified kiwi peel (NA-KP) based adsorbents were prepared and evaluated for selective removal of cationic dye. The morphology and chemical structure of KP and NA-KP were fully characterized and compared, and results showed nitric acid modification introduced more functional groups. Moreover, the adsorption kinetics and isotherms of malachite green (MG) by KP and NA-KP were investigated and discussed. The results showed that the adsorption process of MG onto KP followed a pseudo-second-order kinetic model and the Langmuir isotherm model, while the adsorption process of ...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Yanjun Zhao Xintong Liu Wenhui Li Suyun Pei Yifan Ren Xinyang Li Chen Qu Chuandong Wu Jiemin Liu Tags: Article Source Type: research

Residue levels of organophosphate pesticides and dialkylphosphates in agricultural products in Japan
In this study, we analyzed the levels of OPs and preformed DAPs in various food items. DAP levels were markedly high in certain fruits, such as persimmon, apple juice, kiwi, and mandarin. In contrast, only moderate levels of OPs were detected in these foods. Furthermore, the levels of OPs and DAPs were positively associated with vegetables, whereas no such association was observed in fruits. Increased consumption of certain fruits presumably leads to a marked increase in urinary DAP levels in individuals despite limited exposure to OPs, resulting in reduced reliability of urinary DAPs as a marker of OP exposure. Therefore,...
Source: Environmental Research - July 2, 2023 Category: Environmental Health Authors: Tomoyuki Tsuchiyama Yuki Ito Masaru Taniguchi Miki Katsuhara Hitoshi Miyazaki Michihiro Kamijima Source Type: research

[ASAP] Molecular Mechanism of miR160d in Regulating Kiwifruit Resistance to < named-content content-type="genus-species" xlink:type="simple" > Botrytis cinerea < /named-content >
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.3c02741 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - June 29, 2023 Category: Food Science Authors: Zhexin Li, Shuai Yang, Yijia Ma, Yuan Sui, Haitao Xing, Wenli Zhang, Qinhong Liao, and Yusong Jiang Source Type: research

Novel jointured green synthesis of chitosan ‑silver nanocomposite: An approach towards reduction of nitroarenes, anti-proliferative, wound healing and antioxidant applications
Int J Biol Macromol. 2023 Jun 26:125578. doi: 10.1016/j.ijbiomac.2023.125578. Online ahead of print.ABSTRACTHere we present the simple green synthesis of chitosan‑silver nanocomposite (CS-Ag NC) by employing kiwi fruit juice as reducing agent. The structure, morphology, and composition of CS-Ag NC were determined using characterization techniques such as XRD, SEM-EDX, UV-visible, FT-IR, particle size, and zeta potential. The prepared CS-Ag nanocomposite was effectively used as catalyst in the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) in the presence of NaBH4 as reductant, in aqueous medium at room tempera...
Source: International Journal of Biological Macromolecules - June 28, 2023 Category: Biochemistry Authors: Barnabas Kodasi Ravindra R Kamble Arun K Shettar Joy H Hoskeri Rangappa S Keri Tukaram V Metre Lokesh Bheemayya Vishwa B Nadoni Manojna R Nayak Source Type: research

Molecules, Vol. 28, Pages 4938: Naphthalene-Based Polymers as Catalytic Supports for Suzuki Cross-Coupling
nda Z. Nikoshvili In this work, for the first time, naphthalene (NA)-based polymers were synthesized by one-stage Friedel&amp;ndash;Crafts crosslinking. The influence of NA functionalization by -OH, -SO3H, and -NO2 groups on the polymers&amp;rsquo; porosity and distribution of the catalytically active phase (Pd) was studied. Synthesized catalytic systems containing 1 wt.% of Pd either in the form of Pd(II) species or Pd(0) nanoparticles supported on NA-based polymers were tested in a model reaction of Suzuki cross-coupling between 4-bromoanisole and phenylboronic acid under mild reaction conditions (60 &amp...
Source: Molecules - June 23, 2023 Category: Chemistry Authors: Elena S. Bakhvalova Alexey V. Bykov Mariia E. Markova Yury V. Lugovoy Alexander I. Sidorov Vladimir P. Molchanov Mikhail G. Sulman Lioubov Kiwi-Minsker Linda Z. Nikoshvili Tags: Article Source Type: research

Combining multi-isotope technology, hydrochemical information, and MixSIAR model to identify and quantify nitrate sources of groundwater and surface water in a multi-land use region
Environ Sci Pollut Res Int. 2023 Jun 8. doi: 10.1007/s11356-023-27720-9. Online ahead of print.ABSTRACTAccurate identification of nitrate (NO3-) sources is the premise of non-point source pollution control in watersheds. The multiple isotope techniques (δ15N-NO3-, δ18O-NO3-, δ2H-H2O, δ18O-H2O), combined with hydrochemistry characteristics, land use information, and Bayesian stable isotope mixing model (MixSIAR), were used to identify the sources and contributions of NO3- in the agricultural watershed of the upper Zihe River, China. A total of 43 groundwater (GW) and 7 surface water (SFW) samples were collected. The res...
Source: Environmental Science and Pollution Research International - June 8, 2023 Category: Environmental Health Authors: Wanning Zhao Deqing Yang Qiang Sun Yandong Gan Liyong Bai Shuangshuang Li Dongmei Liu Jiulan Dai Source Type: research