Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
CONCLUSION: NMV/r has significant DDIs with many common dermatological medications, which may require temporary discontinuation, dosage adjustment or substitution with other anti-COVID-19 agents such as molnupiravir.PMID:36592146 | DOI:10.47102/annals-acadmedsg.2022289 (Source: Ann Acad Med Singapo...)
Source: Ann Acad Med Singapo... - January 2, 2023 Category: General Medicine Authors: Kathleen Shu En Quah Xiaoling Huang Laurent Renia Hazel H Oon Source Type: research

Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
CONCLUSION: NMV/r has significant DDIs with many common dermatological medications, which may require temporary discontinuation, dosage adjustment or substitution with other anti-COVID-19 agents such as molnupiravir.PMID:36592146 | DOI:10.47102/annals-acadmedsg.2022289 (Source: Ann Acad Med Singapo...)
Source: Ann Acad Med Singapo... - January 2, 2023 Category: General Medicine Authors: Kathleen Shu En Quah Xiaoling Huang Laurent Renia Hazel H Oon Source Type: research

Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
CONCLUSION: NMV/r has significant DDIs with many common dermatological medications, which may require temporary discontinuation, dosage adjustment or substitution with other anti-COVID-19 agents such as molnupiravir.PMID:36592146 | DOI:10.47102/annals-acadmedsg.2022289 (Source: Ann Acad Med Singapo...)
Source: Ann Acad Med Singapo... - January 2, 2023 Category: General Medicine Authors: Kathleen Shu En Quah Xiaoling Huang Laurent Renia Hazel H Oon Source Type: research

Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
CONCLUSION: NMV/r has significant DDIs with many common dermatological medications, which may require temporary discontinuation, dosage adjustment or substitution with other anti-COVID-19 agents such as molnupiravir.PMID:36592146 | DOI:10.47102/annals-acadmedsg.2022289 (Source: Ann Acad Med Singapo...)
Source: Ann Acad Med Singapo... - January 2, 2023 Category: General Medicine Authors: Kathleen Shu En Quah Xiaoling Huang Laurent Renia Hazel H Oon Source Type: research

Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
CONCLUSION: NMV/r has significant DDIs with many common dermatological medications, which may require temporary discontinuation, dosage adjustment or substitution with other anti-COVID-19 agents such as molnupiravir.PMID:36592146 | DOI:10.47102/annals-acadmedsg.2022289 (Source: Ann Acad Med Singapo...)
Source: Ann Acad Med Singapo... - January 2, 2023 Category: General Medicine Authors: Kathleen Shu En Quah Xiaoling Huang Laurent Renia Hazel H Oon Source Type: research

Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
CONCLUSION: NMV/r has significant DDIs with many common dermatological medications, which may require temporary discontinuation, dosage adjustment or substitution with other anti-COVID-19 agents such as molnupiravir.PMID:36592146 | DOI:10.47102/annals-acadmedsg.2022289 (Source: Ann Acad Med Singapo...)
Source: Ann Acad Med Singapo... - January 2, 2023 Category: General Medicine Authors: Kathleen Shu En Quah Xiaoling Huang Laurent Renia Hazel H Oon Source Type: research

The Interkingdom Interaction with < em > Staphylococcus < /em > Influences the Antifungal Susceptibility of the Cutaneous Fungus Malassezia
This study investigated how the interaction between Malassezia and Staphylococcus affected the antifungal susceptibility of the fungus to the azole antifungal drug ketoconazole. The susceptibility was significantly decreased when Malassezia was co-cultured with Staphylococcus. We found that acidification of the environment by organic acids produced by Staphylococcus influenced the decrease of the ketoconazole susceptibility of M. restricta in the co-culturing condition. Furthermore, our data demonstrated that the significant increased ergosterol content and cell membrane and wall thickness of the M. restricta cells grown i...
Source: Journal of Microbiology and Biotechnology - December 28, 2022 Category: Biotechnology Authors: Juan Yang Sungmin Park Hyun Ju Kim Sang Jun Lee Won Hee Jung Source Type: research

The Interkingdom Interaction with < em > Staphylococcus < /em > Influences the Antifungal Susceptibility of the Cutaneous Fungus Malassezia
This study investigated how the interaction between Malassezia and Staphylococcus affected the antifungal susceptibility of the fungus to the azole antifungal drug ketoconazole. The susceptibility was significantly decreased when Malassezia was co-cultured with Staphylococcus. We found that acidification of the environment by organic acids produced by Staphylococcus influenced the decrease of the ketoconazole susceptibility of M. restricta in the co-culturing condition. Furthermore, our data demonstrated that the significant increased ergosterol content and cell membrane and wall thickness of the M. restricta cells grown i...
Source: Journal of Microbiology and Biotechnology - December 28, 2022 Category: Biotechnology Authors: Juan Yang Sungmin Park Hyun Ju Kim Sang Jun Lee Won Hee Jung Source Type: research

The Interkingdom Interaction with < em > Staphylococcus < /em > Influences the Antifungal Susceptibility of the Cutaneous Fungus Malassezia
This study investigated how the interaction between Malassezia and Staphylococcus affected the antifungal susceptibility of the fungus to the azole antifungal drug ketoconazole. The susceptibility was significantly decreased when Malassezia was co-cultured with Staphylococcus. We found that acidification of the environment by organic acids produced by Staphylococcus influenced the decrease of the ketoconazole susceptibility of M. restricta in the co-culturing condition. Furthermore, our data demonstrated that the significant increased ergosterol content and cell membrane and wall thickness of the M. restricta cells grown i...
Source: Journal of Microbiology and Biotechnology - December 28, 2022 Category: Biotechnology Authors: Juan Yang Sungmin Park Hyun Ju Kim Sang Jun Lee Won Hee Jung Source Type: research

The Interkingdom Interaction with < em > Staphylococcus < /em > Influences the Antifungal Susceptibility of the Cutaneous Fungus Malassezia
This study investigated how the interaction between Malassezia and Staphylococcus affected the antifungal susceptibility of the fungus to the azole antifungal drug ketoconazole. The susceptibility was significantly decreased when Malassezia was co-cultured with Staphylococcus. We found that acidification of the environment by organic acids produced by Staphylococcus influenced the decrease of the ketoconazole susceptibility of M. restricta in the co-culturing condition. Furthermore, our data demonstrated that the significant increased ergosterol content and cell membrane and wall thickness of the M. restricta cells grown i...
Source: Journal of Microbiology and Biotechnology - December 28, 2022 Category: Biotechnology Authors: Juan Yang Sungmin Park Hyun Ju Kim Sang Jun Lee Won Hee Jung Source Type: research

The Interkingdom Interaction with < em > Staphylococcus < /em > Influences the Antifungal Susceptibility of the Cutaneous Fungus Malassezia
This study investigated how the interaction between Malassezia and Staphylococcus affected the antifungal susceptibility of the fungus to the azole antifungal drug ketoconazole. The susceptibility was significantly decreased when Malassezia was co-cultured with Staphylococcus. We found that acidification of the environment by organic acids produced by Staphylococcus influenced the decrease of the ketoconazole susceptibility of M. restricta in the co-culturing condition. Furthermore, our data demonstrated that the significant increased ergosterol content and cell membrane and wall thickness of the M. restricta cells grown i...
Source: Journal of Microbiology and Biotechnology - December 28, 2022 Category: Biotechnology Authors: Juan Yang Sungmin Park Hyun Ju Kim Sang Jun Lee Won Hee Jung Source Type: research

The Interkingdom Interaction with < em > Staphylococcus < /em > Influences the Antifungal Susceptibility of the Cutaneous Fungus Malassezia
This study investigated how the interaction between Malassezia and Staphylococcus affected the antifungal susceptibility of the fungus to the azole antifungal drug ketoconazole. The susceptibility was significantly decreased when Malassezia was co-cultured with Staphylococcus. We found that acidification of the environment by organic acids produced by Staphylococcus influenced the decrease of the ketoconazole susceptibility of M. restricta in the co-culturing condition. Furthermore, our data demonstrated that the significant increased ergosterol content and cell membrane and wall thickness of the M. restricta cells grown i...
Source: Journal of Microbiology and Biotechnology - December 28, 2022 Category: Biotechnology Authors: Juan Yang Sungmin Park Hyun Ju Kim Sang Jun Lee Won Hee Jung Source Type: research

Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: The American Journal of Tropical Medicine and Hygiene - December 26, 2022 Category: Tropical Medicine Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research

Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: Am J Trop Med Hyg - December 26, 2022 Category: Infectious Diseases Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research

Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: The American Journal of Tropical Medicine and Hygiene - December 26, 2022 Category: Tropical Medicine Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research